Published in:
Open Access
14-08-2023 | Pain Syndromes | Original Article
Low-dose radiotherapy for greater trochanteric pain syndrome—a single-centre analysis
Authors:
Michal Staruch, Silvia Gomez, Susanne Rogers, Istvan Takacs, Thomas Kern, Sabine Adler, Dieter Cadosch, Oliver Riesterer
Published in:
Strahlentherapie und Onkologie
|
Issue 2/2024
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Abstract
Purpose
To determine predictive factors associated with a good response (GR) to and efficacy of low-dose radiotherapy (LDRT) in patients with greater trochanteric pain syndrome (GTPS).
Methods
Patients with GTPS were irradiated on a linear accelerator with 0.5–1.0 Gy per fraction to a total dose of 3.0–4.0 Gy per series. The endpoint was subjective good response (GR) to treatment 2 months after completion of the last LDRT series, defined as complete pain relief or marked improvement assessed using the von Pannewitz score. A positive response to steroid injection (SI) was defined as pain relief of at least 7 days. Patient and treatment-related characteristics were evaluated with respect to LDRT outcomes.
Results
Outcomes were assessed for 71 peritrochanteric spaces (PTSs; 65 patients, 48 females, with mean age of 63 [44–91] years). Prior SI had been given to 55 (77%) PTSs and 40 PTSs received two series of LDRT. Two months after completion of LDRT, GR was reported in 42 PTSs (59%). Two series of LDRT provided a significantly higher rate of GR than one series (72.5 vs. 42% PTSs, p = 0.015). Temporary pain relief after prior SI predicted GR to LDRT compared with PTSs which had not responded to SI (73 vs. 28% PTSs, p = 0.001). A regional structural abnormality, present in 34 PTSs (48%), was associated with a reduction of GR to LDRT (44 vs. 73% PTSs, p = 0.017).
Conclusion
LDRT is an effective treatment for GTPS. Administration of two LDRT series, prior response to SI, and absence of structural abnormalities may predict significantly better treatment outcomes.