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Published in: Osteoporosis International 3/2024

Open Access 23-10-2023 | Osteoporosis | Review

Radiomorphometric indices of the mandible as indicators of decreased bone mineral density and osteoporosis – meta-analysis and systematic review

Authors: Joanna Heuchert, Sławomir Kozieł, Anna E. Spinek

Published in: Osteoporosis International | Issue 3/2024

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Abstract

This review aims to evaluate the accuracy of various mandibular radiomorphometric indices in comparison with DEXA BMD measurements in the diagnosis of osteopenia and osteoporosis based on a meta-analysis of the sensitivity and specificity of the indices. PRISMA statement was followed. The materials for analysis were collected in August 2023 by searching three databases: PubMed Central, Web of Science, and Scopus. The selection of studies consisted of three selection stages, and 64 articles were finally obtained. Quality assessment was performed with the QUADAS-2 tool, and the general methodological quality of retrieved studies was low. Statistical analysis was performed based on 2 × 2 tables and estimated sensitivity and specificity were obtained using SROC curves. The most used indices were MCI, MCW and PMI. The best results in detecting reduced BMD obtained for MCW ≤ 3 mm, estimated sensitivity and specificity were 0.712 (95% CI, 0.477–0.870) and 0.804 (95% CI, 0.589–0.921), respectively. The most prone to the risk of bias is the MCI due to the examiner’s subjectivism. Radiomorphometric indices of the mandible can be useful as a screening tool to identify patients with low BMD, but should not be used as a diagnostic method. Further research needs to focus on analysing the ability of the indices to detect osteoporosis and also in combination the indices with clinical parameters.
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Metadata
Title
Radiomorphometric indices of the mandible as indicators of decreased bone mineral density and osteoporosis – meta-analysis and systematic review
Authors
Joanna Heuchert
Sławomir Kozieł
Anna E. Spinek
Publication date
23-10-2023
Publisher
Springer London
Published in
Osteoporosis International / Issue 3/2024
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-023-06949-7

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