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Published in: Endocrine 1/2023

03-10-2022 | Osteoarthrosis | Original Article

Global Burden of osteoarthritis associated with high body mass index in 204 countries and territories, 1990–2019: findings from the Global Burden of Disease Study 2019

Authors: Gaichan Zhao, Shijie Zhu, Faxue Zhang, Xupeng Zhang, Xiaowei Zhang, Tianzhou Li, Dejia Li, Wei Zhu

Published in: Endocrine | Issue 1/2023

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Abstract

Objective

To quantify the burden of osteoarthritis (OA) associated with high body mass index (BMI) across 204 countries and territories from 1990 to 2019.

Methods

This study extracted global, regional, and national data on years lived with disability (YLD) of OA associated with high BMI from GBD 2019. The YLD burden of OA associated with high BMI was systematically analyzed by age, SDI, sex, and EAPC.

Results

At the global level, ~2.67 million (95% UI: 1.04, 5.75) YLD were attributable to OA associated with high BMI, with an age-standardized rate of 31.9 (95% UI: 12.4, 68.75) YLD per 100,000 population in 2019. There was a 0.5 increase (95% UI: 0.35, 0.79) over the 30 years with an EAPC of 1.45. In 2019, Australasia {57.49 (95% UI: 23.62, 125.38)}, high-income North America {56.2 (95% UI: 23.32, 121.97)}, and Andean Latin America {49.77 (95% UI: 19.73, 111.73)} had the highest age-standardized YLD rates. The population aged at 60-74 group had a higher YLD rate for both males and females. Females tended to be more sensitive to the OA associated with high BMI than male in any region.

Conclusions

In summary, the YLD rate of OA associated with high BMI presented a continuous upward trend in most countries. Women and older people are more sensitive to OA due to physiological and psychological factors. Controlling modifiable risk factors such as maintaining an appropriate BMI is needed for disease prevention.
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Metadata
Title
Global Burden of osteoarthritis associated with high body mass index in 204 countries and territories, 1990–2019: findings from the Global Burden of Disease Study 2019
Authors
Gaichan Zhao
Shijie Zhu
Faxue Zhang
Xupeng Zhang
Xiaowei Zhang
Tianzhou Li
Dejia Li
Wei Zhu
Publication date
03-10-2022
Publisher
Springer US
Published in
Endocrine / Issue 1/2023
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-022-03201-w

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