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Knee Surgery, Sports Traumatology, Arthroscopy

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01-11-2019 | Osteoarthrosis | KNEE

Degenerative changes in cartilage likely occur in the medial compartment after anterior cruciate ligament reconstruction

Authors: Tetsuro Ushio, Ken Okazaki, Kanji Osaki, Yukihisa Takayama, Koji Sagiyama, Hideki Mizu-uchi, Satoshi Hamai, Yukio Akasaki, Hiroshi Honda, Yasuharu Nakashima

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 11/2019

Abstract

Purpose

Magnetic resonance imaging with T1ρ mapping is used to quantify the amount of glycosaminoglycan in articular cartilage, which reflects early degenerative changes. The purposes of this study were to evaluate early degenerative changes in knees after anterior cruciate ligament (ACL) reconstruction by comparing T1ρ values before and 2 years after surgery and investigate whether surgical factors and clinical outcomes are related to differences in T1ρ values.

Methods

Fifty patients who underwent unilateral primary ACL reconstruction were evaluated using T1ρ mapping before and 2 years after surgery. Three regions of interest (ROIs) were defined in the cartilage associated with the medial (M) and lateral (L) weight-bearing areas of the femoral condyle (FC) (anterior: MFC1 and LFC1, middle: MFC2 and LFC2, and posterior: MFC3 and LFC3). Two ROIs associated with the tibial plateau (T) were defined (anterior: MT1 and LT1, and posterior: MT2 and LT2). T1ρ values within the ROIs were measured before and 2 years after surgery and compared using the paired t test. Correlations between the difference in T1ρ values at these two time points and patient characteristics, presence of a cartilaginous lesion, graft type, and postoperative anteroposterior laxity were also evaluated using Pearson’s and Spearman’s correlation coefficients.

Results

There was a significant increase in T1ρ before versus 2 years after surgery in the MT1, MT2, LFC1, and LT1 areas, and a significant decrease in the LFC3 and LT2 areas. There was a significant correlation between postoperative anterior-posterior laxity and a postoperative increase in T1ρ values in the MFC3 (r = 0.37, P = 0.013) and MT2 (r = 0.35, P = 0.021) areas. Increases in T1ρ values in the MFC2 area were negatively correlated with KOOS symptoms (ρ = − 0.349, P = 0.027) and quality of life (ρ = − 0.374, P = 0.017) subscale scores.

Conclusion

Early degenerative changes in medial articular cartilage were observed with T1ρ mapping at 2 years after ACL reconstruction. Postoperative anterior-posterior laxity is correlated with an increase in T1ρ values in the posteromedial femur and tibia. An increase in T1ρ values in the central medial femoral condyle was associated with knee symptoms.

Level of evidence

III.

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Title: Degenerative changes in cartilage likely occur in the medial compartment after anterior cruciate ligament reconstruction
Authors: Tetsuro Ushio
Ken Okazaki
Kanji Osaki
Yukihisa Takayama
Koji Sagiyama
Hideki Mizu-uchi
Satoshi Hamai
Yukio Akasaki
Hiroshi Honda
Yasuharu Nakashima
Publication date: 01-11-2019
Publisher: Springer Berlin Heidelberg
Keywords: Osteoarthrosis
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Osteoarthrosis
Helminths
Published in: Knee Surgery, Sports Traumatology, Arthroscopy / Issue 11/2019
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-019-05468-5

At a glance: The STEP trials

Springer Medicine

Degenerative changes in cartilage likely occur in the medial compartment after anterior cruciate ligament reconstruction

Abstract

Purpose

Methods

Results

Conclusion

Level of evidence

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

Level of evidence

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