Skip to main content
Top
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 11/2019

01-11-2019 | KNEE

Small hamstring autograft is defined by a cut-off diameter of 7 mm and not recommended with allograft augmentation in single-bundle ACL reconstruction

Authors: Huijun Kang, Conglei Dong, Fei Wang

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 11/2019

Login to get access

Abstract

Purpose

The present study was to analyze graft failure rates of hamstring tendon (HT) autografts with a cut-off graft diameter of 8 mm or 7 mm, and compare clinical outcomes between augmented small HT with an allograft and non-augmented relatively large HT in single-bundle anterior cruciate ligament reconstruction (ACLR).

Methods

A literature search of PubMed, EMBASE, and the Cochrane Library was performed based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analysis) guidelines. Studies to assess graft failure of autologous HT ACLR were reviewed, and graft failure rates with a cut-off graft diameter of 8 mm or 7 mm were further extracted. Clinical comparative studies of ACLR between augmented small HT with an allograft and non-augmented relatively large HT autografts were also included. Results are presented as risk ratio (RR) for binary data and weighted mean difference for continuous data with 95% confidence intervals (CI).

Results

Nine studies with 2243 knees were included. Four studies examined the effect of HT autograft diameter on graft failure and five studies assessed clinical outcomes of allograft augmentation to small HT autografts. No significant difference was noted in graft failure with a cut-off diameter of 8 mm. No significant difference was found between diameters > 7 and ≤ 7 mm, but a significant difference was observed between diameters ≥ 7 and < 7 mm (RR = 0.49; 95% CI 0.26–0.92, I2 = 0%, P = 0.03). A trend towards increased risk of graft failure was noted for allograft-augmented HT compared with non-augmented HT autografts (RR = 0.43; 95% CI 0.18–1.02, I2 = 0%), but no significant differences were noted in IKDC, Lysholm, and Tegner scores between these groups.

Conclusion

The present study did support the use of 7 mm as a reference for cut-off diameter for small HT autografts, but not allograft augmentation to small HT autografts. These findings would guide clinical application of small HT autografts in single-bundle ACLR.

Level of evidence

IV.
Appendix
Available only for authorised users
Literature
1.
go back to reference Andernord D, Bjornsson H, Petzold M, Eriksson BI, Forssblad M, Karlsson J, Samuelsson K (2014) Surgical predictors of early revision surgery after anterior cruciate ligament reconstruction: results from the swedish national knee ligament register on 13,102 patients. Am J Sports Med 42(7):1574–1582CrossRef Andernord D, Bjornsson H, Petzold M, Eriksson BI, Forssblad M, Karlsson J, Samuelsson K (2014) Surgical predictors of early revision surgery after anterior cruciate ligament reconstruction: results from the swedish national knee ligament register on 13,102 patients. Am J Sports Med 42(7):1574–1582CrossRef
2.
go back to reference Boniello MR, Schwingler PM, Bonner JM, Robinson SP, Cotter A, Bonner KF (2015) Impact of hamstring graft diameter on tendon strength: a biomechanical study. Arthroscopy 31(6):1084–1090CrossRef Boniello MR, Schwingler PM, Bonner JM, Robinson SP, Cotter A, Bonner KF (2015) Impact of hamstring graft diameter on tendon strength: a biomechanical study. Arthroscopy 31(6):1084–1090CrossRef
3.
go back to reference Burrus MT, Werner BC, Crow AJ et al. (2015) Increased failure rates after anterior cruciate ligament reconstruction with soft-tissue autograft-allograft hybrid grafts. Arthroscopy 31:2342–2351CrossRef Burrus MT, Werner BC, Crow AJ et al. (2015) Increased failure rates after anterior cruciate ligament reconstruction with soft-tissue autograft-allograft hybrid grafts. Arthroscopy 31:2342–2351CrossRef
4.
go back to reference Conte EJ, Hyatt AE, Gatt CJ Jr, Dhawan A (2014) Hamstring autograft size can be predicted and is a potential risk factor for anterior cruciate ligament reconstruction failure. Arthroscopy 30(7):882–890CrossRef Conte EJ, Hyatt AE, Gatt CJ Jr, Dhawan A (2014) Hamstring autograft size can be predicted and is a potential risk factor for anterior cruciate ligament reconstruction failure. Arthroscopy 30(7):882–890CrossRef
5.
go back to reference Darnley JE, Leger-St-Jean B, Pedroza AD, Flanigan DC, Kaeding CC, Magnussen RA (2016) Anterior cruciate ligament reconstruction using a combination of autograft and allograft tendon: a MOON cohort study. Orthop J Sports Med 4:2325967116662249CrossRef Darnley JE, Leger-St-Jean B, Pedroza AD, Flanigan DC, Kaeding CC, Magnussen RA (2016) Anterior cruciate ligament reconstruction using a combination of autograft and allograft tendon: a MOON cohort study. Orthop J Sports Med 4:2325967116662249CrossRef
6.
go back to reference DiBartola AC, Everhart JS, Kaeding CC, Magnussen RA, Flanigan DC (2016) Maximum load to failure of high dose versus low dose gamma irradiation of anterior cruciate ligament allografts: a meta-analysis. Knee 23:755–762CrossRef DiBartola AC, Everhart JS, Kaeding CC, Magnussen RA, Flanigan DC (2016) Maximum load to failure of high dose versus low dose gamma irradiation of anterior cruciate ligament allografts: a meta-analysis. Knee 23:755–762CrossRef
7.
go back to reference Farmer K, Kenney N, Moser M, Conrad B (2013) Biomechanical qualities of small size hamstring grafts: how small is too small? Arthroscopy 29(10):e145–e146CrossRef Farmer K, Kenney N, Moser M, Conrad B (2013) Biomechanical qualities of small size hamstring grafts: how small is too small? Arthroscopy 29(10):e145–e146CrossRef
8.
go back to reference Figueroa F, Figueroa D, Espregueira-Mendes J (2018) Hamstring autograft size importance in anterior cruciate ligament repair surgery. EFORT Open Rev 3(3):93–97CrossRef Figueroa F, Figueroa D, Espregueira-Mendes J (2018) Hamstring autograft size importance in anterior cruciate ligament repair surgery. EFORT Open Rev 3(3):93–97CrossRef
9.
go back to reference Kopf S, Pombo MW, Szczodry M, Irrgang JJ, Fu FH (2011) Size variability of the human anterior cruciate ligament insertion sites. Am J Sports Med 39(1):108–113CrossRef Kopf S, Pombo MW, Szczodry M, Irrgang JJ, Fu FH (2011) Size variability of the human anterior cruciate ligament insertion sites. Am J Sports Med 39(1):108–113CrossRef
10.
go back to reference Leo BM, Krill M, Barksdale L, Alvarez-Pinzon AM (2016) Failure rate and clinical outcomes of anterior cruciate ligament reconstruction using autograft hamstring versus a hybrid graft. Arthroscopy 32:2357–2363CrossRef Leo BM, Krill M, Barksdale L, Alvarez-Pinzon AM (2016) Failure rate and clinical outcomes of anterior cruciate ligament reconstruction using autograft hamstring versus a hybrid graft. Arthroscopy 32:2357–2363CrossRef
11.
go back to reference Li J, Wang J, Li Y, Shao D, You X, Shen Y (2015) A prospective randomized study of anterior cruciate ligament reconstruction with autograft, gamma-irradiated allograft, and hybrid graft. Arthroscopy 31:1296–1302CrossRef Li J, Wang J, Li Y, Shao D, You X, Shen Y (2015) A prospective randomized study of anterior cruciate ligament reconstruction with autograft, gamma-irradiated allograft, and hybrid graft. Arthroscopy 31:1296–1302CrossRef
12.
go back to reference Magnussen RA, Kaeding CC, Taylor DC (2015) Solutions to small hamstring autograft harvest: a survey of the ACL study group. Curr Orthop Pract 26(1):43–44CrossRef Magnussen RA, Kaeding CC, Taylor DC (2015) Solutions to small hamstring autograft harvest: a survey of the ACL study group. Curr Orthop Pract 26(1):43–44CrossRef
13.
go back to reference Mariscalco MW, Flanigan DC, Mitchell J et al. (2013) The influence of hamstring autograft size on patient-reported outcomes and risk of revision after anterior cruciate ligament reconstruction: a multicenter orthopaedic outcomes network (MOON) cohort study. Arthroscopy 29(12):1948–1953CrossRef Mariscalco MW, Flanigan DC, Mitchell J et al. (2013) The influence of hamstring autograft size on patient-reported outcomes and risk of revision after anterior cruciate ligament reconstruction: a multicenter orthopaedic outcomes network (MOON) cohort study. Arthroscopy 29(12):1948–1953CrossRef
14.
go back to reference Noyes FR, Butler DL, Grood ES, Zernicke RF, Hefzy MS (1984) Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions. J Bone Joint Surg Am 66:344–352CrossRef Noyes FR, Butler DL, Grood ES, Zernicke RF, Hefzy MS (1984) Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions. J Bone Joint Surg Am 66:344–352CrossRef
15.
go back to reference Park SY, Oh H, Park S, Lee JH, Lee SH, Yoon KH (2013) Factors predicting hamstring tendon autograft diameters and resulting failure rates after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 21(5):1111–1118CrossRef Park SY, Oh H, Park S, Lee JH, Lee SH, Yoon KH (2013) Factors predicting hamstring tendon autograft diameters and resulting failure rates after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 21(5):1111–1118CrossRef
16.
go back to reference Pennock AT, Ho B, Parvanta K, Edmonds EW, Chambers HG, Roocroft JH, Bastrom TP (2017) Does allograft augmentation of small-diameter hamstring autograft ACL grafts reduce the incidence of graft retear? Am J Sports Med 45(2):334–338CrossRef Pennock AT, Ho B, Parvanta K, Edmonds EW, Chambers HG, Roocroft JH, Bastrom TP (2017) Does allograft augmentation of small-diameter hamstring autograft ACL grafts reduce the incidence of graft retear? Am J Sports Med 45(2):334–338CrossRef
17.
go back to reference Schimoler PJ, Braun DT, Miller MC, Akhavan S (2015) Quadrupled hamstring graft strength as a function of clinical sizing. Arthroscopy 31(6):1091–1096CrossRef Schimoler PJ, Braun DT, Miller MC, Akhavan S (2015) Quadrupled hamstring graft strength as a function of clinical sizing. Arthroscopy 31(6):1091–1096CrossRef
18.
go back to reference Snaebjörnsson T, Hamrin Senorski E, Ayeni OR et al. (2017) Graft diameter as a predictor for revision anterior cruciate ligament reconstruction and KOOS and EQ-5D values: a cohort study from the Swedish national knee ligament register based on 2240 patients. Am J Sports Med 45(9):2092–2097CrossRef Snaebjörnsson T, Hamrin Senorski E, Ayeni OR et al. (2017) Graft diameter as a predictor for revision anterior cruciate ligament reconstruction and KOOS and EQ-5D values: a cohort study from the Swedish national knee ligament register based on 2240 patients. Am J Sports Med 45(9):2092–2097CrossRef
19.
go back to reference Spragg L, Chen J, Mirzayan R, Love R, Maletis G (2016) The effect of autologous hamstring graft diameter on the likelihood for revision of anterior cruciate ligament reconstruction. Am J Sports Med 44(6):1475–1481CrossRef Spragg L, Chen J, Mirzayan R, Love R, Maletis G (2016) The effect of autologous hamstring graft diameter on the likelihood for revision of anterior cruciate ligament reconstruction. Am J Sports Med 44(6):1475–1481CrossRef
20.
go back to reference Wang HD, Gao SJ, Zhang YZ (2018) Comparison of clinical outcomes after anterior cruciate ligament reconstruction using a hybrid graft versus a hamstring autograft. Arthroscopy 34(5):1508–1516CrossRef Wang HD, Gao SJ, Zhang YZ (2018) Comparison of clinical outcomes after anterior cruciate ligament reconstruction using a hybrid graft versus a hamstring autograft. Arthroscopy 34(5):1508–1516CrossRef
21.
go back to reference Webster KE, Feller JA, Leigh WB, Richmond AK (2014) Younger patients are at increased risk of graft rupture and contralateral injury after anterior cruciate ligament reconstruction. Am J Sports Med 42(3):641–647CrossRef Webster KE, Feller JA, Leigh WB, Richmond AK (2014) Younger patients are at increased risk of graft rupture and contralateral injury after anterior cruciate ligament reconstruction. Am J Sports Med 42(3):641–647CrossRef
22.
go back to reference Wells GA, Shea B, O’Connell D et al (2011) The Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in metaanalyses. Ottawa Hospital Research Institute, Ottawa Wells GA, Shea B, O’Connell D et al (2011) The Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in metaanalyses. Ottawa Hospital Research Institute, Ottawa
23.
go back to reference Wernecke GC, Constantinidis A, Harris IA, Seeto BG, Chen DB, MacDessi SJ (2017) The diameter of single bundle, hamstring autograft does not significantly influence revision rate or clinical outcomes after anterior cruciate ligament reconstruction. Knee 24(5):1033–1038CrossRef Wernecke GC, Constantinidis A, Harris IA, Seeto BG, Chen DB, MacDessi SJ (2017) The diameter of single bundle, hamstring autograft does not significantly influence revision rate or clinical outcomes after anterior cruciate ligament reconstruction. Knee 24(5):1033–1038CrossRef
24.
go back to reference Wydra FB, York PJ, Johnson CR, Silvestri L (2016) Allografts for ligament reconstruction: where are we now? Am J Orthop (Belle Mead NJ) 45(7):446–453 Wydra FB, York PJ, Johnson CR, Silvestri L (2016) Allografts for ligament reconstruction: where are we now? Am J Orthop (Belle Mead NJ) 45(7):446–453
25.
go back to reference Xu H, Dong J, Xin D, Zhang J, Kang K, Gao S (2017) Second-look arthroscopic evaluation and clinical outcomes of anatomic anterior cruciate ligament reconstruction with autograft and hybrid graft: a retrospective study. Med Sci Monit 23:5564–5573CrossRef Xu H, Dong J, Xin D, Zhang J, Kang K, Gao S (2017) Second-look arthroscopic evaluation and clinical outcomes of anatomic anterior cruciate ligament reconstruction with autograft and hybrid graft: a retrospective study. Med Sci Monit 23:5564–5573CrossRef
Metadata
Title
Small hamstring autograft is defined by a cut-off diameter of 7 mm and not recommended with allograft augmentation in single-bundle ACL reconstruction
Authors
Huijun Kang
Conglei Dong
Fei Wang
Publication date
01-11-2019
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 11/2019
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-019-05475-6

Other articles of this Issue 11/2019

Knee Surgery, Sports Traumatology, Arthroscopy 11/2019 Go to the issue