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Modern Rheumatology
Published in: Modern Rheumatology 3/2008

01-06-2008 | Case Report

Ossification of the posterior longitudinal ligament in dizygotic twins with schizophrenia: a case report

Authors: Shunji Matsunaga, Hiroaki Koga, Naoya Kawabata, Ichiro Kawamura, Masaki Otusji, Takanori Imakiire, Setsuro Komiya

Published in: Modern Rheumatology | Issue 3/2008

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Abstract

The pathogenesis of ossification of the posterior longitudinal ligaments (OPLL) has not been clarified. We here report dizygotic twin sisters with OPLL of the cervical spine and propose a new pathogenesis of OPLL. This is the first report of dizygotic twins with OPLL. The twins suffered from schizophrenia, which might be related to the pathogenesis of OPLL. In addition, we investigated the occurrence of OPLL in 30 patients with schizophrenia who had been admitted to a mental hospital. OPLL of the cervical spine was found in six (20%) of them, with an incidence almost five times higher than the incidence of OPLL among the general population in Japan. Schizophrenia may have a increased susceptibility to OPLL.
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Metadata
Title
Ossification of the posterior longitudinal ligament in dizygotic twins with schizophrenia: a case report
Authors
Shunji Matsunaga
Hiroaki Koga
Naoya Kawabata
Ichiro Kawamura
Masaki Otusji
Takanori Imakiire
Setsuro Komiya
Publication date
01-06-2008
Publisher
Springer Japan
Published in
Modern Rheumatology / Issue 3/2008
Print ISSN: 1439-7595
Electronic ISSN: 1439-7609
DOI
https://doi.org/10.1007/s10165-008-0036-1

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