Published in:
01-10-2007 | Abstracts
Oral Presentations
Authors:
B. M. Verdel, E. P. van Puijenbroek, P. C. Souverein, H. G. M. van Leufkens, A. C. G. Egberts
Published in:
Drug Safety
|
Issue 10/2007
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Excerpt
Background: Drug-induced ototoxicity is a subject of interest, as many diseases are treated with drugs which have potential toxic effects on the ear. There is evidence that both inner ear and kidney tissue are immunologically, biochemically and functionally related. It has been suggested that drugs affecting transport of sodium and/or potassium change ionic homeostasis in the inner ear, hence inducing functional disturbances, such as hearing loss, tinnitus and vertigo. …