Published in:
01-10-2007 | Abstracts
Poster Presentations
Authors:
A. S. Lemaire-Hurtel, L. Masson, L. Harry, H. Masson, M. Andrejak
Published in:
Drug Safety
|
Issue 10/2007
Login to get access
Excerpt
Tipranavir is a second-generation dihydropyrone against HIV. This sulphonamide derivative is a nonpeptidic protease inhibitor (NPPI) with a resistance profile distinct from other currently available protease inhibitors (PIs). Concomitant administration of a low-dose of ritonavir (RTV) significantly increases tipranavir (TPV) plasma concentrations. The approved dose of tipranavir is 500 mg with ritonavir 200 mg, twice daily.[1] …