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Current Allergy and Asthma Reports
Published in: Current Allergy and Asthma Reports 6/2010

01-11-2010

Oral Food Desensitization

Authors: Todd D. Green, A. Wesley Burks

Published in: Current Allergy and Asthma Reports | Issue 6/2010

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Abstract

The immunologic interactions in the gastrointestinal tract are extensive and complex. In most cases, the end result of this activity is one of tolerance, which refers to the inhibition of an immune response. However, in a minority of cases, food allergy develops, and this seems to be increasing in prevalence. We continue to learn about the mechanisms involved in these processes and the factors that may promote tolerance as opposed to allergy. At this point, management of food allergy consists of allergen avoidance and readiness to manage an accidental exposure reaction, but using current knowledge of gastrointestinal immunity, researchers are investigating immunomodulatory approaches that will provide “active” therapy for food allergy and induce tolerance. Oral immunotherapy is one important therapy being studied, and in this article, we review recent results from studies of this potential treatment for food allergy.
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Metadata
Title
Oral Food Desensitization
Authors
Todd D. Green
A. Wesley Burks
Publication date
01-11-2010
Publisher
Current Science Inc.
Published in
Current Allergy and Asthma Reports / Issue 6/2010
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-010-0142-y

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