Published in:
01-03-2016 | Editorial
Oral antiviral therapy reduces the risk of hepatocellular carcinoma in persons with chronic hepatitis B infection: combining evidence and common sense
Authors:
Yuanyuan Kong, Hong You, Jidong Jia
Published in:
Hepatology International
|
Issue 2/2016
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Excerpt
According to a recent global systemic review, in 2010 about 248 million persons in the general population worldwide were chronically infected with hepatitis B virus (HBV), with the highest HBsAg prevalence rates being in Africa (8.83 %) and the Western Pacific region (5.26 %) [
1]. Universal HBV vaccination programs in newborns have led a remarkable decline in HBsAg prevalence among young age groups in many countries such as China [
2], but the huge number of persons with chronic HBV infection, if left untreated, will still cause an enormous disease burden associated with cirrhosis and hepatocellular carcinoma (HCC) in the next decades [
3]. …