Skip to main content
Top
Published in: Acta Neurochirurgica 11/2018

Open Access 01-11-2018 | Case Report - Brain trauma

Optimal cerebral perfusion pressure via transcranial Doppler in TBI: application of robotic technology

Authors: Frederick A. Zeiler, Marek Czosnyka, Peter Smielewski

Published in: Acta Neurochirurgica | Issue 11/2018

Login to get access

Abstract

Individualized cerebral perfusion pressure (CPP) targets may be derived via assessing the minimum of the parabolic relationship between an index of cerebrovascular reactivity and CPP. This minimum is termed the optimal CPP (CPPopt), and literature suggests that the further away CPP is from CPPopt, the worse is clinical outcome in adult traumatic brain injury (TBI). Typically, CPPopt estimation is based on intracranial pressure (ICP)-derived cerebrovascular reactivity indices, given ICP is commonly measured and provides continuous long duration data streams. The goal of this study is to describe for the first time the application of robotic transcranial Doppler (TCD) and the feasibility of determining CPPopt based on TCD autoregulation indices.
Appendix
Available only for authorised users
Literature
1.
go back to reference Aries MJH, Czosnyka M, Budohoski KP et al (2012) Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury. Crit Care Med 40(8):2456–2463CrossRefPubMed Aries MJH, Czosnyka M, Budohoski KP et al (2012) Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury. Crit Care Med 40(8):2456–2463CrossRefPubMed
2.
go back to reference Aries MJH, Wesselink R, Elting JWJ, Donnelly J, Czosnyka M, Ercole A, Maurits NM, Smielewski P (2016) Enhanced visualization of optimal cerebral perfusion pressure over time to support clinical decision making. Crit Care Med 44(10):e996–e999CrossRefPubMed Aries MJH, Wesselink R, Elting JWJ, Donnelly J, Czosnyka M, Ercole A, Maurits NM, Smielewski P (2016) Enhanced visualization of optimal cerebral perfusion pressure over time to support clinical decision making. Crit Care Med 44(10):e996–e999CrossRefPubMed
3.
go back to reference Blanco P (2016) Transcranial color-coded duplex sonography: another option besides the blind method. J Ultrasound Med 35(3):669–671CrossRefPubMed Blanco P (2016) Transcranial color-coded duplex sonography: another option besides the blind method. J Ultrasound Med 35(3):669–671CrossRefPubMed
4.
go back to reference Brady KM, Lee JK, Kibler KK, Easley RB, Koehler RC, Shaffner DH (2008) Continuous measurement of autoregulation by spontaneous fluctuations in cerebral perfusion pressure: comparison of 3 methods. Stroke 39(9):2531–2537CrossRefPubMedPubMedCentral Brady KM, Lee JK, Kibler KK, Easley RB, Koehler RC, Shaffner DH (2008) Continuous measurement of autoregulation by spontaneous fluctuations in cerebral perfusion pressure: comparison of 3 methods. Stroke 39(9):2531–2537CrossRefPubMedPubMedCentral
5.
go back to reference British Medical Ultrasound Society (2012) The British Medical Ultrasound Society: guidelines for the safe use of diagnostic ultrasound equipment British Medical Ultrasound Society (2012) The British Medical Ultrasound Society: guidelines for the safe use of diagnostic ultrasound equipment
6.
go back to reference Budohoski KP, Reinhard M, Aries MJH, Czosnyka Z, Smielewski P, Pickard JD, Kirkpatrick PJ, Czosnyka M (2012) Monitoring cerebral autoregulation after head injury. Which component of transcranial Doppler flow velocity is optimal? Neurocrit Care 17(2):211–218CrossRefPubMed Budohoski KP, Reinhard M, Aries MJH, Czosnyka Z, Smielewski P, Pickard JD, Kirkpatrick PJ, Czosnyka M (2012) Monitoring cerebral autoregulation after head injury. Which component of transcranial Doppler flow velocity is optimal? Neurocrit Care 17(2):211–218CrossRefPubMed
7.
go back to reference Calviello LA, de Riva N, Donnelly J, Czosnyka M, Smielewski P, Menon DK, Zeiler FA (2017) Relationship between brain pulsatility and cerebral perfusion pressure: replicated validation using different drivers of CPP change. Neurocrit Care 27(3):392–400CrossRefPubMedPubMedCentral Calviello LA, de Riva N, Donnelly J, Czosnyka M, Smielewski P, Menon DK, Zeiler FA (2017) Relationship between brain pulsatility and cerebral perfusion pressure: replicated validation using different drivers of CPP change. Neurocrit Care 27(3):392–400CrossRefPubMedPubMedCentral
8.
go back to reference Cardim D, Robba C, Bohdanowicz M, Donnelly J, Cabella B, Liu X, Cabeleira M, Smielewski P, Schmidt B, Czosnyka M (2016) Non-invasive monitoring of intracranial pressure using transcranial Doppler ultrasonography: is it possible? Neurocrit Care 25(3):473–491CrossRefPubMedPubMedCentral Cardim D, Robba C, Bohdanowicz M, Donnelly J, Cabella B, Liu X, Cabeleira M, Smielewski P, Schmidt B, Czosnyka M (2016) Non-invasive monitoring of intracranial pressure using transcranial Doppler ultrasonography: is it possible? Neurocrit Care 25(3):473–491CrossRefPubMedPubMedCentral
9.
go back to reference Carney N, Totten AM, O’Reilly C et al (2017) Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery 80(1):6–15PubMed Carney N, Totten AM, O’Reilly C et al (2017) Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery 80(1):6–15PubMed
10.
go back to reference Czosnyka M, Miller C, Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring (2014) Monitoring of cerebral autoregulation. Neurocrit Care 21 Suppl 2:S95–102 Czosnyka M, Miller C, Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring (2014) Monitoring of cerebral autoregulation. Neurocrit Care 21 Suppl 2:S95–102
11.
go back to reference Czosnyka M, Smielewski P, Kirkpatrick P, Laing RJ, Menon D, Pickard JD (1997) Continuous assessment of the cerebral vasomotor reactivity in head injury. Neurosurgery 41(1):11–17 discussion 17-19CrossRefPubMed Czosnyka M, Smielewski P, Kirkpatrick P, Laing RJ, Menon D, Pickard JD (1997) Continuous assessment of the cerebral vasomotor reactivity in head injury. Neurosurgery 41(1):11–17 discussion 17-19CrossRefPubMed
12.
go back to reference ter Haar G (2012) The safe use of ultrasound in medical diagnosis, 3rd edn. The British Institute of Radiology, LondonCrossRef ter Haar G (2012) The safe use of ultrasound in medical diagnosis, 3rd edn. The British Institute of Radiology, LondonCrossRef
13.
go back to reference Harris GR, Church CC, Dalecki D, Ziskin MC, Bagley JE, American Institute of Ultrasound in Medicine, Health Canada, British Medical Ultrasound Society (2016) Comparison of thermal safety practice guidelines for diagnostic ultrasound exposures. Ultrasound Med Biol 42(2):345–357CrossRefPubMed Harris GR, Church CC, Dalecki D, Ziskin MC, Bagley JE, American Institute of Ultrasound in Medicine, Health Canada, British Medical Ultrasound Society (2016) Comparison of thermal safety practice guidelines for diagnostic ultrasound exposures. Ultrasound Med Biol 42(2):345–357CrossRefPubMed
14.
go back to reference Howells T, Smielewski P, Donnelly J, Czosnyka M, Hutchinson PJA, Menon DK, Enblad P, Aries MJH (2018) Optimal cerebral perfusion pressure in centers with different treatment protocols. Crit Care Med 46(3):e235–e241CrossRefPubMed Howells T, Smielewski P, Donnelly J, Czosnyka M, Hutchinson PJA, Menon DK, Enblad P, Aries MJH (2018) Optimal cerebral perfusion pressure in centers with different treatment protocols. Crit Care Med 46(3):e235–e241CrossRefPubMed
15.
16.
go back to reference Le Roux P, Menon DK, Citerio G et al (2014) The international multidisciplinary consensus conference on multimodality monitoring in neurocritical care: evidentiary tables: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine. Neurocrit Care 21(Suppl 2):S297–S361CrossRefPubMed Le Roux P, Menon DK, Citerio G et al (2014) The international multidisciplinary consensus conference on multimodality monitoring in neurocritical care: evidentiary tables: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine. Neurocrit Care 21(Suppl 2):S297–S361CrossRefPubMed
17.
go back to reference Liu X, Maurits NM, Aries MJH et al (2017) Monitoring of optimal cerebral perfusion pressure in traumatic brain injured patients using a multi-window weighting algorithm. J Neurotrauma 34(22):3081–3088CrossRefPubMed Liu X, Maurits NM, Aries MJH et al (2017) Monitoring of optimal cerebral perfusion pressure in traumatic brain injured patients using a multi-window weighting algorithm. J Neurotrauma 34(22):3081–3088CrossRefPubMed
18.
go back to reference Mackinnon AD, Aaslid R, Markus HS (2004) Long-term ambulatory monitoring for cerebral emboli using transcranial Doppler ultrasound. Stroke 35(1):73–78CrossRefPubMed Mackinnon AD, Aaslid R, Markus HS (2004) Long-term ambulatory monitoring for cerebral emboli using transcranial Doppler ultrasound. Stroke 35(1):73–78CrossRefPubMed
19.
go back to reference Needham E, McFadyen C, Newcombe V, Synnot AJ, Czosnyka M, Menon D (2017) Cerebral perfusion pressure targets individualized to pressure-reactivity index in moderate to severe traumatic brain injury: a systematic review. J Neurotrauma 34(5):963–970CrossRefPubMed Needham E, McFadyen C, Newcombe V, Synnot AJ, Czosnyka M, Menon D (2017) Cerebral perfusion pressure targets individualized to pressure-reactivity index in moderate to severe traumatic brain injury: a systematic review. J Neurotrauma 34(5):963–970CrossRefPubMed
20.
go back to reference Postert T, Federlein J, Przuntek H, Büttner T (1998) Comparison of transcranial power Doppler and contrast-enhanced color-coded sonography in the identification of intracranial arteries. J Ultrasound Med 17(2):91–96CrossRefPubMed Postert T, Federlein J, Przuntek H, Büttner T (1998) Comparison of transcranial power Doppler and contrast-enhanced color-coded sonography in the identification of intracranial arteries. J Ultrasound Med 17(2):91–96CrossRefPubMed
22.
go back to reference Sorrentino E, Budohoski KP, Kasprowicz M, Smielewski P, Matta B, Pickard JD, Czosnyka M (2011) Critical thresholds for transcranial Doppler indices of cerebral autoregulation in traumatic brain injury. Neurocrit Care 14(2):188–193CrossRefPubMed Sorrentino E, Budohoski KP, Kasprowicz M, Smielewski P, Matta B, Pickard JD, Czosnyka M (2011) Critical thresholds for transcranial Doppler indices of cerebral autoregulation in traumatic brain injury. Neurocrit Care 14(2):188–193CrossRefPubMed
23.
go back to reference Sorrentino E, Diedler J, Kasprowicz M et al (2012) Critical thresholds for cerebrovascular reactivity after traumatic brain injury. Neurocrit Care 16(2):258–266CrossRefPubMed Sorrentino E, Diedler J, Kasprowicz M et al (2012) Critical thresholds for cerebrovascular reactivity after traumatic brain injury. Neurocrit Care 16(2):258–266CrossRefPubMed
24.
go back to reference Steiner LA, Czosnyka M, Piechnik SK, Smielewski P, Chatfield D, Menon DK, Pickard JD (2002) Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Crit Care Med 30(4):733–738CrossRefPubMed Steiner LA, Czosnyka M, Piechnik SK, Smielewski P, Chatfield D, Menon DK, Pickard JD (2002) Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Crit Care Med 30(4):733–738CrossRefPubMed
25.
go back to reference Thiara S, Griesdale DE, Henderson WR, Sekhon MS (2018) Effect of cerebral perfusion pressure on acute respiratory distress syndrome. Can J Neurol Sci:1–7 Thiara S, Griesdale DE, Henderson WR, Sekhon MS (2018) Effect of cerebral perfusion pressure on acute respiratory distress syndrome. Can J Neurol Sci:1–7
26.
go back to reference Varsos GV, Kasprowicz M, Smielewski P, Czosnyka M (2014) Model-based indices describing cerebrovascular dynamics. Neurocrit Care 20(1):142–157CrossRefPubMed Varsos GV, Kasprowicz M, Smielewski P, Czosnyka M (2014) Model-based indices describing cerebrovascular dynamics. Neurocrit Care 20(1):142–157CrossRefPubMed
27.
go back to reference Varsos GV, Kolias AG, Smielewski P, Brady KM, Varsos VG, Hutchinson PJ, Pickard JD, Czosnyka M (2015) A noninvasive estimation of cerebral perfusion pressure using critical closing pressure. J Neurosurg 123(3):638–648CrossRefPubMed Varsos GV, Kolias AG, Smielewski P, Brady KM, Varsos VG, Hutchinson PJ, Pickard JD, Czosnyka M (2015) A noninvasive estimation of cerebral perfusion pressure using critical closing pressure. J Neurosurg 123(3):638–648CrossRefPubMed
28.
go back to reference Watt BP (2012) Design and development of a novel transcranial Doppler headset for assessment of cerebral blood flow. Thesis, University of Nebraska Watt BP (2012) Design and development of a novel transcranial Doppler headset for assessment of cerebral blood flow. Thesis, University of Nebraska
29.
go back to reference Zeiler F (2018) Cerebral perfusion pressure targets in traumatic brain injury: the “fuzzy” spots above optimal cerebral perfusion pressure. Can J Neurol Sci In Press Zeiler F (2018) Cerebral perfusion pressure targets in traumatic brain injury: the “fuzzy” spots above optimal cerebral perfusion pressure. Can J Neurol Sci In Press
30.
go back to reference Zeiler FA, Cardim D, Donnelly J, Menon DK, Czosnyka M, Smielewski P (2018) Transcranial Doppler systolic flow index and ICP-derived cerebrovascular reactivity indices in traumatic brain injury. J Neurotrauma 35(2):314–322CrossRefPubMed Zeiler FA, Cardim D, Donnelly J, Menon DK, Czosnyka M, Smielewski P (2018) Transcranial Doppler systolic flow index and ICP-derived cerebrovascular reactivity indices in traumatic brain injury. J Neurotrauma 35(2):314–322CrossRefPubMed
31.
go back to reference Zeiler FA, Donnelly J, Calviello L, Menon DK, Smielewski P, Czosnyka M (2017) Pressure autoregulation measurement techniques in adult traumatic brain injury, part I: a scoping review of intermittent/semi-intermittent methods. J Neurotrauma 34(23):3207–3223CrossRefPubMed Zeiler FA, Donnelly J, Calviello L, Menon DK, Smielewski P, Czosnyka M (2017) Pressure autoregulation measurement techniques in adult traumatic brain injury, part I: a scoping review of intermittent/semi-intermittent methods. J Neurotrauma 34(23):3207–3223CrossRefPubMed
32.
go back to reference Zeiler FA, Donnelly J, Calviello L, Smielewski P, Menon DK, Czosnyka M (2017) Pressure autoregulation measurement techniques in adult traumatic brain injury, part II: a scoping review of continuous methods. J Neurotrauma 34(23):3224–3237CrossRefPubMed Zeiler FA, Donnelly J, Calviello L, Smielewski P, Menon DK, Czosnyka M (2017) Pressure autoregulation measurement techniques in adult traumatic brain injury, part II: a scoping review of continuous methods. J Neurotrauma 34(23):3224–3237CrossRefPubMed
34.
go back to reference Zeiler FA, Smielewski P (2018) Application of robotic transcranial Doppler for extended duration recording in moderate/severe traumatic brain injury: first experiences. Crit Ultrasound J 10(1):16CrossRefPubMedPubMedCentral Zeiler FA, Smielewski P (2018) Application of robotic transcranial Doppler for extended duration recording in moderate/severe traumatic brain injury: first experiences. Crit Ultrasound J 10(1):16CrossRefPubMedPubMedCentral
Metadata
Title
Optimal cerebral perfusion pressure via transcranial Doppler in TBI: application of robotic technology
Authors
Frederick A. Zeiler
Marek Czosnyka
Peter Smielewski
Publication date
01-11-2018
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 11/2018
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-018-3687-5

Other articles of this Issue 11/2018

Acta Neurochirurgica 11/2018 Go to the issue