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Open Access 01-07-2021 | Optic Neuritis | Letter to the Editor

Clinical characteristics of MOG antibody disease: two case reports

Authors: Yujia Guan, Zunwei Zhang, Mingming Li, Miao Shi, Hui Deng

Published in: Neurological Sciences | Issue 7/2021

Excerpt

Serum myelin oligodendrocyte glycoprotein (MOG) antibody-mediated idiopathic inflammatory demyelinating disease (IIDDs), a type of central nervous system demyelinating disease with MOG antibodies positive in serum, referred to as MOG antibody disease. This is different from multiple sclerosis (MS) or optic neuromyelitis lineage disease (NMOSD) because of its relatively unique clinical features, imaging findings, and special biomarkers, and it is now considered to be an independent disease. Disease syndrome mainly includes single or bilateral optic neuritis (ON), long-segment transverse myelitis (LETM), transverse myelitis (TM), optic neuritis plus transverse myelitis (ON+TM)/AQP4 antibody-negative NMOSD, and acute disseminated encephalomyelitis (ADEM) [1]. In order to further understand the clinical characteristics of MOG antibody disease, we present two patients with MOG antibody disease admitted in our hospital. …

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Title: Clinical characteristics of MOG antibody disease: two case reports
Authors: Yujia Guan
Zunwei Zhang
Mingming Li
Miao Shi
Hui Deng
Publication date: 01-07-2021
Publisher: Springer International Publishing
Keyword: Optic Neuritis
Published in: Neurological Sciences / Issue 7/2021
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-021-05122-4

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Clinical characteristics of MOG antibody disease: two case reports

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