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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2020

01-12-2020 | Opioids | Review

Postoperative pain pathophysiology and treatment strategies after CRS + HIPEC for peritoneal cancer

Authors: Xiao Wang, Tianzuo Li

Published in: World Journal of Surgical Oncology | Issue 1/2020

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Abstract

Background

Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment choice for peritoneal cancer. However, patients commonly suffer from severe postoperative pain. The pathophysiology of postoperative pain is considered to be from both nociceptive and neuropathic origins.

Main body

The recent advances on the etiology of postoperative pain after CRS + HIPEC treatment were described, and the treatment strategy and outcomes were summarized.

Conclusion

Conventional analgesics could provide short-term symptomatic relief. Thoracic epidural analgesia combined with opioids administration could be an effective treatment choice. In addition, a transversus abdominis plane block could also be an alternative option, although further studies should be performed.
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Metadata
Title
Postoperative pain pathophysiology and treatment strategies after CRS + HIPEC for peritoneal cancer
Authors
Xiao Wang
Tianzuo Li
Publication date
01-12-2020
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2020
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-020-01842-7

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