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Open Access 19-12-2023 | Original Article

Ongoing impacts of childhood-onset glomerular diseases during young adulthood

Authors: Keishiro Furuie, Shohei Kuraoka, Hideki Ban, Yuko Hidaka, Hiroko Nagata, Hiroshi Tamura, Koji Nagano, Tomoyasu Kawano, Akio Furuse, Hitoshi Nakazato, Kimitoshi Nakamura

Published in: Pediatric Nephrology | Issue 6/2024

Abstract

Background

Childhood-onset glomerular disease often requires ongoing treatment and follow-up into adulthood. However, few studies have analyzed the associated impact and distress experienced by patients with this condition during the transition from childhood to adolescence and adulthood.

Methods

At three facilities, we recruited patients who developed idiopathic nephrotic syndrome or IgA nephropathy during childhood and were at least 18 years old at the time of study entry. Among them, a questionnaire-based survey was administered to patients who consented to participate, and the results were analyzed in conjunction with clinical information.

Results

Data from a total of 38 patients were analyzed. Of these patients, 15 had idiopathic nephrotic syndrome and 23 had IgA nephropathy. The age of transition from pediatrics to the adult medicine department was correlated with the number of recurrences. Many patients also reported being significantly affected by exercise restrictions and physical decline associated with their diseases and medications. Various impacts, including distress, affected decision-making regarding higher education, with patients engaging in higher education at a significantly higher rate compared with the regional average (66.7% vs. 46.9%, p = 0.028).

Conclusion

We analyzed the impact of childhood-onset glomerular disease and distress during the transition period from pediatric to adult care. This study highlighted the significant impact of medications and exercise restrictions on patients’ decisions regarding higher education. Future prospective studies will be needed to examine patients’ distress in more detail and establish management approaches to enhance patient quality of life.

Graphical abstract

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Title: Ongoing impacts of childhood-onset glomerular diseases during young adulthood
Authors: Keishiro Furuie
Shohei Kuraoka
Hideki Ban
Yuko Hidaka
Hiroko Nagata
Hiroshi Tamura
Koji Nagano
Tomoyasu Kawano
Akio Furuse
Hitoshi Nakazato
Kimitoshi Nakamura
Publication date: 19-12-2023
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Nephrology / Issue 6/2024
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-023-06250-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Ongoing impacts of childhood-onset glomerular diseases during young adulthood

Abstract

Background

Methods

Results

Conclusion

Graphical abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

Graphical abstract

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