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BMC Pediatrics
Published in: BMC Pediatrics 1/2016

Open Access 01-12-2016 | Research article

One-year effects of two intensive inpatient treatments for severely obese children and adolescents

Authors: Sabine Makkes, Carry M. Renders, Judith E. Bosmans, Olga H. van der Baan-Slootweg, Trynke Hoekstra, Jacob C. Seidell

Published in: BMC Pediatrics | Issue 1/2016

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Abstract

Background

Intensive inpatient lifestyle treatment may be a suitable alternative for severely obese children and adolescents who do not benefit from ambulatory obesity treatment.
The aim was to evaluate the effectiveness of two intensive one-year lifestyle treatments with varying inpatient periods for severely obese children and adolescents with regard to SDS-BMI and cardiometabolic risk factors.

Methods

The study was designed as a randomized controlled trial with two active treatment groups.
Eighty participants (8–19 years) with severe obesity received treatment at a specialized childhood obesity center in the Netherlands. Severe obesity was defined as a SDS-BMI ≥ 3.0 or a SDS-BMI ≥ 2.3 in combination with obesity-related comorbidity.
Participants received an intensive one-year lifestyle treatment with an inpatient period of either two months and biweekly return visits during the next four months (short-stay group) or six months (long-stay group), both followed by six monthly return visits.
Outcomes were assessed at baseline, six and 12 months and included SDS-BMI as primary outcome and cardiometabolic risk factors such as SDS-waist circumference, systolic- and diastolic blood pressure, and blood measurements as secondary outcomes.
To evaluate differences in the course of the primary- and secondary outcomes over time between the two treatment groups, Generalized Estimating Equations (GEE) were performed.

Results

No differences in the course of SDS-BMI or secondary outcomes over time were found between the two treatment groups after one year of treatment. SDS-BMI decreased statistically significantly after one year of treatment compared with baseline in both groups (0.33 (0.48) in the short-stay and 0.52 (0.49) in the long-stay group). Similar results were found for SDS-waist circumference, diastolic blood pressure and HDL-cholesterol.

Conclusions

Since there were no significant differences in effects between the short- and long-stay treatment and considering the burden of the long-stay treatment for children and families, we recommend implementation of the short-stay treatment.

Trial registration

Netherlands Trial Register NTR1678, registered 20-Feb-2009
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Metadata
Title
One-year effects of two intensive inpatient treatments for severely obese children and adolescents
Authors
Sabine Makkes
Carry M. Renders
Judith E. Bosmans
Olga H. van der Baan-Slootweg
Trynke Hoekstra
Jacob C. Seidell
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2016
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-016-0659-x

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