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BMC Pediatrics
Published in: BMC Pediatrics 1/2016

Open Access 01-12-2016 | Research article

Associated factors and persistence of palatal groove in preterm infants: a cohort study

Authors: Andréa A. O. Cortines, Luciane R. Costa

Published in: BMC Pediatrics | Issue 1/2016

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Abstract

Background

There is a lack of evidence on the relationship between prematurity and palatal abnormalities. The aim of this study was to evaluate the incidence of palatal groove, the associated factors and the persistence time in preterm infants from birth to 24 months of age.

Methods

The children’s data, medical history and eating habits were collected using a questionnaire answered by the legal guardian and updated every dental visit. Natal and neonatal data were obtained from the medical records. During the orofacial examination, the presence or absence of a palatal groove was observed. In order to evaluate for associations between independent variables and the palatal groove, descriptive analyses and bivariate analyses were conducted using the Mann-Whitney, Pearson’s chi-squared and Fisher’s exact tests, when appropriate. The Poisson regression analysis was used to determine risk and protective factors for the occurrence of palatal groove. The significance level was 0.05. For the persistence of palatal groove, a survival analysis was used (Kaplan Meier method).

Results

Seventy-four preterm infants were monitored. Palatal groove occurred in n = 19 (25.7 %) and persisted for an average time of 12 months. Bivariate analysis showed a significantly higher occurrence of palatal groove in girls (68.4 % vs 40 % with non-occurrence of palatal groove) as well as in infants that stayed longer in the neonatal intensive care unit (NICU) (median 37 days vs 20 days), that did not have exclusive breastfeeding (94.7 % vs 69.1 %), were intubated (median five days vs one day) or used an orogastric tube (median 33 days vs 15 days). The quantitative data for ‘NICU’, ‘intubation’ and ‘orogastric tube’ were correlated and estimated as risk factors for palatal groove formation in the unadjusted Poisson regression analysis.

Conclusions

Palatal groove occur transiently in approximately one quarter of preterm infants, especially in infants that stay longer in the NICU, are intubated or use an orogastric tube.
Literature
1.
WHO, March of Dimes, PMNCH, Save the Children. In: Howson CP, Kinney MV, Lawn JE, editors. Born Too Soon: The Global Action Report on Preterm Birth. Geneva: World Health Organization; 2012.
2.
Caixeta FF, Correa MSNP. Evaluation of dental eruption pattern and of enamel defects in the premature child. Rev Assoc Med Bras. 2005;51:195–9.CrossRefPubMed
3.
Germa A, Marret S, Thiriez G, Rousseau S, Hascoët JM, Paulsson-Björnsson L, et al. Neonatal factors associated with alteration of palatal morphology in very preterm children: the EPIPAGE cohort study. Early Hum Dev. 2012;88:413–20.CrossRefPubMed
4.
Paulsson L, Bondemark L, Söderfeldt B. A systematic review of the consequences of premature birth on palatal morphology, dental occlusion, tooth-crown dimensions, and tooth maturity and eruption. Angle Orthod. 2004;74:269–79.PubMed
5.
Hohoff A, Rabe H, Ehmer U, Harms E. Palatal development of preterm and low birthweight infants compared to term infants - What do we know? Part 1: The palate of the term newborn. Head Face Med. 2005;1:8.CrossRefPubMedPubMedCentral
6.
Seow WK, Brown JP, Tudehope DI, O’Callaghan M. Effect of neonatal laryngoscopy and endotracheal intubation on palatal symmetry in two- to five-year-old children. Pediatr Dent. 1985;7:30–6.
7.
Kopra DE, Davis EL. Prevalence of oral defects among neonatally intubated 3- to 5- and 7- to 10-year old children. Pediatr Dent. 1991;13:349–55.PubMed
8.
Fadavi S, Adeni S, Dziedzic K, Punwani I, Vidyasagar D. The oral effects of orotracheal intubation in prematurely born preschoolers. J Dent Child. 1992;59:420–4.
9.
10.
Macey-Dare LV, Moles DR, Evans RD, Nixon F. Long-term effect of neonatal endotracheal intubation on palatal form and symmetry in 8-11-year-old children. Eur J Orthod. 1999;21:703–10.CrossRefPubMed
11.
Alves PVM, Luiz RR. The influence of orotracheal intubation on the oral tissue development in preterm infants. Oral Health Prev Dent. 2012;10:141–7.PubMed
12.
Hohoff A, Rabe H, Ehmer U, Harms E. Palatal development of preterm and low birthweight infants compared to term infants - What do we know? Part 2: The palate of the preterm/low birthweight infant. Head Face Med. 2005;1:9.CrossRefPubMedPubMedCentral
13.
Hohoff A, Rabe H, Ehmer U, Harms E. Palatal development of preterm and low birthweight infants compared to term infants - What do we know? Part 3: discussion and conclusion. Head Face Med. 2005;1:10.CrossRefPubMedPubMedCentral
14.
Erenberg A, Nowak AJ. Palatal groove formation in neonates and infants with orotracheal tubes. Am J Dis Child. 1984;138:974–5.PubMed
15.
Laowansiri U, Beherents RG, Araujo E, Oliver DR, Buschang PH. Maxillary growth and maturation during infancy and early childhood. Angle Orthod. 2013;83:563–71.CrossRefPubMed
16.
Ash SP, Moss JP. An investigation of the features of the pre-term infant and the effect of prolonged orotracheal intubation with and without protection appliances. Br J Orthod. 1987;14:253–61.CrossRefPubMed
Metadata
Title
Associated factors and persistence of palatal groove in preterm infants: a cohort study
Authors
Andréa A. O. Cortines
Luciane R. Costa
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2016
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-016-0671-1

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