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Gut Pathogens
Published in: Gut Pathogens 1/2018

Open Access 01-12-2018 | Research

Occurrence of multidrug-resistant and ESBL-producing atypical enteropathogenic Escherichia coli in China

Authors: Yanmei Xu, Hui Sun, Xiangning Bai, Shanshan Fu, Ruyue Fan, Yanwen Xiong

Published in: Gut Pathogens | Issue 1/2018

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Abstract

Background

Atypical enteropathogenic Escherichia coli (aEPEC) is regarded as a globally emerging enteropathogen. aEPECs exhibit various level of resistance to a range of antibiotics, which is increasing alarmingly. The present study investigated the antimicrobial resistance of aEPEC isolates recovered from diarrheal patients, healthy carriers, animals, and raw meats.

Results

Among 267 aEPEC isolates, 146 (54.7%) were resistant to tetracycline, followed by ampicillin (49.4%), streptomycin (46.1%), and piperacillin (41.2%). Multidrug resistance (MDR) was detected in 128 (47.9%) isolates, and 40 MDR isolates were resistant to ≥ 10 antimicrobial agents. A total of 47 (17.6%) aEPEC isolates were identified as extended-spectrum β-lactamase (ESBL)-producers. The blaCTX-M-14 and blaCTX-M-15 genes were predominant among ESBL-producing isolates.

Conclusions

This investigation depicted the occurrence of multidrug-resistant and ESBL-producing aEPEC isolates in China. The results suggested that it is necessary to continuously monitor the emergence and spread of MDR aEPEC.
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Metadata
Title
Occurrence of multidrug-resistant and ESBL-producing atypical enteropathogenic Escherichia coli in China
Authors
Yanmei Xu
Hui Sun
Xiangning Bai
Shanshan Fu
Ruyue Fan
Yanwen Xiong
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Gut Pathogens / Issue 1/2018
Electronic ISSN: 1757-4749
DOI
https://doi.org/10.1186/s13099-018-0234-0

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