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Open Access 01-12-2013 | Case report

Obstructive jaundice due to ampullary metastasis of renal cell carcinoma

Authors: Andreas Karakatsanis, Antonios Vezakis, Georgios Fragulidis, Chryssa Staikou, Eleni E Carvounis, Andreas Polydorou

Published in: World Journal of Surgical Oncology | Issue 1/2013

Abstract

Renal cell carcinoma is often characterized by the presence of metachronous metastases in unusual sites. The presence of isolated metastases is treated with surgical excision with good anticipated results. On the other hand, systemic chemotherapy is administered in the context of metastatic spread, usually sunitib or sorafenib. In such cases, however, the presence of symptomatic foci calls for minimal intervention.

We present a case of a 77-year-old patient who presented with obstructive jaundice due to an ampullary mass. Endoscopic excision and biopsy set the diagnosis of metastatic renal cell carcinoma. Consequently, imaging studies revealed the presence of multiple foci in the lungs and bone. Therefore, pancreatoduodenectomy was excluded and the patient underwent endoscopic ampullectomy and was set to oral sunitinib. Interestingly, despite generalized spread, local control was achieved until the patient succumbed to carcinomatosis.

Painless obstructive jaundice in a patient with history of renal cancer and negative computed tomography scanning for pancreatic or other causes of obstruction should alert for prompt investigation for an ampullary metastasis.

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Title: Obstructive jaundice due to ampullary metastasis of renal cell carcinoma
Authors: Andreas Karakatsanis
Antonios Vezakis
Georgios Fragulidis
Chryssa Staikou
Eleni E Carvounis
Andreas Polydorou
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2013
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-11-262

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Obstructive jaundice due to ampullary metastasis of renal cell carcinoma

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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