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BMC Psychiatry
Published in: BMC Psychiatry 1/2024

Open Access 01-12-2024 | Obsessive-Compulsive Disorder | Study Protocol

A mobile app to challenge obsessional beliefs in adolescents: a protocol of a two-armed, parallel randomized controlled trial

Authors: Yuliya Saman, Belén Pascual-Vera, Marta Corberán, Sandra Arnáez, María Roncero, Gemma García-Soriano

Published in: BMC Psychiatry | Issue 1/2024

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Abstract

Background

Adolescence is a crucial stage for the development of OCD symptoms that, in most cases, persist into adulthood. This requires designing preventive strategies tailored to this population. Therefore, we aim to describe the study protocol that will be used to examine the effectiveness of a mobile health application to challenge obsessional beliefs in adolescents.

Methods

A two-armed randomized controlled trial will be conducted on an adolescent sample from the general population. The experimental group will use the intervention module (GGOC-AD) of a mobile app on the GGtude platform for 14 days whereas the control group will use a non-active module (GGN-AD) of said app. Primary outcome measures will be obsessional beliefs and obsessive-compulsive symptoms, and secondary measures will be self-esteem and emotional symptoms. Three assessment points will be conducted at baseline, post-intervention, and one-month follow-up. A linear multiple regression model with an intention to treat approach will be used. The expected total sample size will be 55 participants.

Discussion

We expect that the intervention group will show a reduction in obsessional beliefs and OCD-symptoms at post and follow-up in comparison with the control group. Additionally, we expect that the app will improve participants’ self-esteem. This study could provide an accessible mobile health tool to prevent OCD-related symptoms in adolescents.

Trial registration

ClinicalTrials.gov identifier: NCT06033391. Registered September 4, 2023.

Graphical Abstract

Appendix
Available only for authorised users
Literature
1.
Canals J, Hernández-Martínez C, Cosi S, Voltas N. The epidemiology of obsessive–compulsive disorder in Spanish school children. J Anxiety Disord. 2012;26(7):746–52.CrossRefPubMed
2.
Nazeer A, Latif F, Mondal A, Azeem MW, Greydanus DE. Obsessive-compulsive disorder in children and adolescents: epidemiology, diagnosis and management. Transl Pediatr. 2020;9(S1):S76–93.CrossRefPubMedPubMedCentral
3.
Dell’Osso B, Benatti B, Hollander E, Fineberg N, Stein DJ, Lochner C, et al. Childhood, adolescent and adult age at onset and related clinical correlates in obsessive–compulsive disorder: a report from the International College of Obsessive–Compulsive Spectrum Disorders (ICOCS). Int J Psychiatry Clin Pract. 2016;20(4):210–7.CrossRefPubMed
4.
Liu J, Cui Y, Yu L, Wen F, Wang F, Yan J, et al. Long-term outcome of pediatric obsessive-compulsive disorder: a meta-analysis. J Child Adolesc Psychopharmacol. 2021;31(2):95–101.CrossRefPubMed
5.
Storch EA, Geffken GR, Murphy TK. Handbook of child and adolescent obsessive-compulsive disorder. Routledge; 2007.CrossRef
6.
Storch EA, Small BJ, McGuire JF, Murphy TK, Wilhelm S, Geller DA. Quality of life in children and youth with obsessive-compulsive disorder. J Child Adolesc Psychopharmacol. 2018;28(2):104–10.CrossRefPubMedPubMedCentral
7.
Stewart SE, Geller DA, Jenike M, Pauls D, Shaw D, Mullin B, et al. Long-term outcome of pediatric obsessive–compulsive disorder: a meta-analysis and qualitative review of the literature. Acta Psychiatr Scand. 2004;110(1):4–13.CrossRefPubMed
8.
9.
del Valle G, Belloch A, Carrió C. The long and complex road in the search for treatment for mental disorders: an analysis of the process in five groups of patients. Psychiatry Res. 2017;253:1–8.CrossRefPubMed
10.
García-Soriano G, Rufer M, Delsignore A, Weidt S. Factors associated with non-treatment or delayed treatment seeking in OCD sufferers: a review of the literature. Psychiatry Res. 2014;220(1–2):1–10.CrossRefPubMed
11.
McKay D, Sookman D, Neziroglu F, Wilhelm S, Stein DJ, Kyrios M, et al. Efficacy of cognitive-behavioral therapy for obsessive-compulsive disorder. Psychiatry Res. 2015;227(1):104–13.CrossRefPubMed
12.
Price M, Yuen EK, Goetter EM, Herbert JD, Forman EM, Acierno R, et al. mHealth: a mechanism to deliver more accessible, more effective mental health care: MHealth opportunities. Clin Psychol Psychother. 2014;21(5):427–36.CrossRefPubMed
13.
Wolters LH, op de Beek V, Weidle B, Skokauskas N. How can technology enhance cognitive behavioral therapy: the case of pediatric obsessive compulsive disorder. BMC Psychiatry. 2017;17(1).
14.
Chaves A, Arnáez S, Castilla D, Roncero M, García-Soriano G. Enhancing mental health literacy in obsessive-compulsive disorder and reducing stigma via smartphone: a randomized controlled trial protocol. Internet Interv. 2022;29:100560.CrossRefPubMedPubMedCentral
15.
Cerea S, Doron G, Manoli T, Patania F, Bottesi G, Ghisi M. Cognitive training via a mobile application to reduce some forms of body dissatisfaction in young females at high-risk for body image disorders: a randomized controlled trial. Body Image. 2022;42:297–306.CrossRefPubMed
16.
17.
Giraldo-O’Meara M, Doron G. Can self-esteem be improved using short daily training on mobile applications? Examining real world data of GG self-esteem users. Clin Psychol (Aust Psychol Soc). 2021;25(2):131–9.
18.
Roncero M, Belloch A, Doron G. A novel approach to challenging OCD related beliefs using a mobile-app: an exploratory study. J Behav Ther Exp Psychiatry. 2018;59:157–60.CrossRefPubMed
19.
Abramowitz JS. The psychological treatment of obsessive—compulsive disorder. Can J Psychiatr. 2006;51(7):407–16.CrossRef
20.
21.
Roncero M, Belloch A, Doron G. Can brief, daily training using a mobile app help change maladaptive beliefs? Crossover randomized controlled trial. JMIR MHealth UHealth. 2019;7(2):e11443.CrossRefPubMedPubMedCentral
22.
Cerea S, Ghisi M, Bottesi G, Carraro E, Broggio D, Doron G. Reaching reliable change using short, daily, cognitive training exercises delivered on a mobile application: the case of relationship obsessive compulsive disorder (ROCD) symptoms and cognitions in a subclinical cohort. J Affect Disord. 2020;276:775–87.CrossRefPubMed
23.
Akin-Sari B, Inozu M, Haciomeroglu AB, Cekci BC, Uzumcu E, Doron G. Cognitive training via a mobile application to reduce obsessive-compulsive-related distress and cognitions during the COVID-19 outbreaks: a randomized controlled trial using a subclinical cohort. Behav Ther. 2022;53(5):776–92.CrossRefPubMedPubMedCentral
24.
Pascual-Vera B, Roncero M, Doron G, Belloch A. Assisting relapse prevention in OCD using a novel mobile app-based intervention: a case report. Bull Menn Clin. 2018;82(4):390–406.CrossRef
25.
Freeman JB, Choate-Summers ML, Moore PS, Garcia AM, Sapyta JJ, Leonard HL, et al. Cognitive behavioral treatment for young children with obsessive-compulsive disorder. Biol Psychiatry. 2007;61(3):337–43.CrossRefPubMedPubMedCentral
26.
Fontenelle LF, Nicolini H, Brakoulias V. Early intervention in obsessive-compulsive disorder: from theory to practice. Compr Psychiatry. 2022;119(152353).
27.
Foa EB, Coles M, Huppert JD, Pasupuleti RV, Franklin ME, March J. Development and validation of a child version of the obsessive compulsive inventory. Behav Ther. 2010;41(1):121–32.CrossRefPubMed
28.
Rosa-Alcázar AI, Ruiz-García B, Iniesta-Sepúlveda M, López-Pina JA, Rosa-Alcázar Á, Parada-Navas JL. Obsessive compulsive inventory-child version (OCI-CV) in a Spanish community sample of children and adolescents. Psicothema. 2014;26(2):174–9.PubMed
29.
Coles ME, Wolters LH, Sochting I, de Haan E, Pietrefesa AS, Whiteside SP. Development and initial validation of the obsessive belief questionnaire-child version (OBQ-CV). Depress Anxiety. 2010;27(10):982–91.CrossRefPubMed
30.
Nogueira Arjona R, Godoy Ávila A, Romero Sanchíz P, Gavino Lázaro A, Cobos Álvarez MP. Psychometric properties of the Spanish version of the obsessive belief questionnaire-Children’s version in a non-clinical sample. Psicothema. 2012;24(4):674–9.PubMed
31.
Johnson JG, Harris ES, Spitzer RL, Williams JBW. The patient health questionnaire for adolescents: validation of an instrument for the assessment of mental disorders among adolescent primary care patients. J Adolesc Health. 2002;30(3):196–204.CrossRefPubMed
32.
33.
Lenz AS, Li C. Evidence for measurement invariance and psychometric reliability for scores on the PHQ-4 from a rural and predominately Hispanic community. Meas Eval Couns Dev. 2022;55(1):17–29.CrossRef
34.
Robins RW, Hendin HM, Trzesniewski KH. Measuring global self-esteem: construct validation of a single-item measure and the Rosenberg self-esteem scale. Personal Soc Psychol Bull. 2001;27(2):151–61.CrossRef
35.
Faul F, Erdfelder E, Lang A-G, Buchner A. G*power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39(2):175–91.CrossRefPubMed
36.
37.
Pozza A, Albert U, Dèttore D. Perfectionism and intolerance of uncertainty are predictors of OCD symptoms in children and early adolescents: a prospective, cohort, one-year, follow-up study. Clin Neuropsychiatry. 2019;16(1):53–61.PubMedPubMedCentral
38.
Pozza A, Mucci F, Marazziti D. Risk for pathological contamination fears at coronavirus time: proposal of early intervention and prevention strategies. Clin Neuropsychiatry. 2020;17(2):100–2.PubMedPubMedCentral
39.
Wolters LH, Hogendoorn SM, Koolstra T, Vervoort L, Boer F, Prins PJM, et al. Psychometric properties of a Dutch version of the obsessive beliefs questionnaire—child version (OBQ-CV). J Anxiety Disord. 2011;25(5):714–21.CrossRefPubMed
40.
Jaeger T, Moulding R, Yang YH, David J, Knight T, Norberg MM. A systematic review of obsessive-compulsive disorder and self: self-esteem, feared self, self-ambivalence, egodystonicity, early maladaptive schemas, and self concealment. J Obsessive Compuls Relat Disord. 2021;31(100665):1–47.
41.
Llorens-Aguilar S, Arnáez S, Aardema F, García-Soriano G. The relationship between obsessions and the self: feared and actual self-descriptions in a clinical obsessive-compulsive disorder sample. Clin Psychol Psychother. 2022;29(2):642–51.CrossRefPubMed
42.
García-Soriano G, Belloch A. Exploring the role of obsessive-compulsive relevant self-worth contingencies in obsessive-compulsive disorder patients. Psychiatry Res. 2012;198(1):94–9.CrossRefPubMed
Metadata
Title
A mobile app to challenge obsessional beliefs in adolescents: a protocol of a two-armed, parallel randomized controlled trial
Authors
Yuliya Saman
Belén Pascual-Vera
Marta Corberán
Sandra Arnáez
María Roncero
Gemma García-Soriano
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2024
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-024-05735-x

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