Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Netherlands Heart Journal
Published in: Netherlands Heart Journal 1/2018

Open Access 01-01-2018 | Editor’s Comment

Non-obstructive cardiovascular disease: a new challenge for invasive cardiology?

Authors: M. E. Wittekoek, J. J. Piek

Published in: Netherlands Heart Journal | Issue 1/2018

Login to get access

Excerpt

Cardiovascular disease is the leading cause of death worldwide, and coronary artery disease (CAD) is the most common type of heart disease. Up to 20–30% of patients presenting with chest discomfort demonstrate no signs of obstructive CAD. In the field of invasive cardiology more than 50% of the patients undergoing coronary angiography for non-acute chest pain have normal or near normal coronary arteries [1]. Non-obstructive CAD in acute coronary syndromes has attracted much attention because of the relatively high incidence of adverse cardiovascular events if not appropriately diagnosed and treated [2]. …
Literature
1.
Patell MR, Peterson ED, Dai D, et al. Low diagnostic yield of elective coronary angiography. N Engl J Med. 2010;363:498.
2.
Pepine CJ, et al. Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia results from the National Heart, Lung and Blood Institute WISE study. J Am Coll Cardiol. 2010;55:2832.CrossRef
3.
Sedlak TL, Lee M, Izadnegahdar M, et al. Sex differences in clinical outcomes in patients with stable angina and no obstructive coronary artery disease. Am Heart J. 2013;166:1:38–44.CrossRef
4.
5.
Humphries KH, Pu A, Gao M. Angina with ‘normal’ coronary arteries: sex differences in outcomes. Am Heart J. 2008;155:375–81.CrossRefPubMed
6.
7.
Parsyan A, Pilote L. Cardiac syndrome X: mystery continues. Can J Cardiol. 2012;28(2 Suppl):S3–S6.CrossRefPubMed
8.
Kaski JC, Rosano GM, Collins P. Cardiac syndrome X: clinical characteristics and left ventricular function. Long-term follow-up study. J Am Coll Cardiol. 1995;25:807–14.CrossRefPubMed
9.
Jadhav ST, Ferrell WR, Petrie JR, et al. Microvascular function, metabolic syndrome, and novel risk factor status in women with cardiac syndrome X. Am J Cardiol. 2006;97:1727–31.CrossRefPubMed
10.
11.
Ong P, Athanasiadis A, Borgulya G. Clinical usefulness, angiographic characteristics, and safety evaluation of intracoronary acetylcholine provocation testing among 921 consecutive white patients with unobstructed coronary arteries. Circulation. 2014;129:1723–30.CrossRefPubMed
Metadata
Title
Non-obstructive cardiovascular disease: a new challenge for invasive cardiology?
Authors
M. E. Wittekoek
J. J. Piek
Publication date
01-01-2018
Publisher
Bohn Stafleu van Loghum
Published in
Netherlands Heart Journal / Issue 1/2018
Print ISSN: 1568-5888
Electronic ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-017-1062-4

Other articles of this Issue 1/2018

Netherlands Heart Journal 1/2018 Go to the issue

Image Puzzle – Question

Total eclipse in the heart

Original Article

Circumstances and causes of sudden circulatory arrests in the Dutch province of Limburg and the involvement of citizen rescuers

Original Article

Role of cardiovascular magnetic resonance in suspected cardiac amyloidosis: late gadolinium enhancement pattern as mortality predictor

Point of View

Percutaneous closure of a patent foramen ovale after cryptogenic stroke

Original Article

Long-term outcomes of a Caucasian cohort presenting with acute coronary syndrome and/or out-of-hospital cardiac arrest caused by coronary spasm

Point of View

Gold open access: the best of both worlds

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits