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Open Access 01-12-2017 | Research article

Non-adherence to anti-retroviral therapy among HIV infected adults in Mon State of Myanmar

Authors: Win Lei Aye, Apa Puckpinyo, Karl Peltzer

Published in: BMC Public Health | Issue 1/2017

Abstract

Background

The provision of Anti-Retroviral Therapy (ART) was started in Myanmar in 2005 in collaboration with the National AIDS Program and the private sector. Successful clinical management of HIV-infected patients is subject to optimal adherence. The aim of the study was to determine the prevalence of adherence to ART and identify factors associated with non-adherence to ART among HIV infected adults registered in a private sector setting in Mon State, Myanmar.

Methods

This cross-sectional study was conducted with adults living with HIV receiving ART at an HIV outpatient clinic between April and May 2016. A total of three hundred People Living with HIV(PLHIV) were interviewed using a pretested and structured questionnaire. The 30 days Visual Analog Scale (VAS) adherence instrument was used to assess the level of adherence. Multivariable logistic regression analysis was used to determine factors associated with non-adherence to ART.

Results

Among 300 patients (male 37.7% and female 62.3%, with a mean age of 41.3 years, standard deviation 8.7), 84% reported ≥95% adherence to ART in the past month. Among 16% of those reporting non-adherence, major reasons for skipping the medication were being busy (23%), being away from home (17.7%) and being forgetful (12.3%). In multivariable logistic rgeression, low behavioural skills on ART adherence (OR = 0.31, 95% CI: 0.10-0.94), tobacco use (OR = 3.22, 95% CI:1.28-8.12), having disclosed their HIV status (OR = 0.07, 95% CI: 0.01-0.69), having a partner who was not on ART (OR = 4.25, 95% CI: 1.70-10.64) and among men, having erectile dysfunction (OR = 15.14, 95% CI: 1.41-162.66) were significant associated with ART non-adherence.

Conclusion

Non-adherence to ART was associated with individual moderating factors and behavioral skills. Priority measures such as addressing risk behaviour and behavioural change communication tailored to individual patients’ lifestyles requires comprehensive interventions to improve adherence.

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Title: Non-adherence to anti-retroviral therapy among HIV infected adults in Mon State of Myanmar
Authors: Win Lei Aye
Apa Puckpinyo
Karl Peltzer
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: BMC Public Health / Issue 1/2017
Electronic ISSN: 1471-2458
DOI: https://doi.org/10.1186/s12889-017-4309-5

At a glance: The STEP trials

Springer Medicine

Non-adherence to anti-retroviral therapy among HIV infected adults in Mon State of Myanmar

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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