Published in:
01-04-2019 | Letter to the Editor
Nivolumab-induced fulminant type 1 diabetes (T1D): the first Italian case report with long follow-up and flash glucose monitoring
Authors:
Francesco Tassone, Ida Colantonio, Elena Gamarra, Laura Gianotti, Claudia Baffoni, Giampaolo Magro, Giorgio Borretta
Published in:
Acta Diabetologica
|
Issue 4/2019
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Excerpt
Nivolumab, an Immune Checkpoint Inhibitor (ICI) against programmed death-1 receptors expressed on T-lymphocytes, has been approved by the Food and Drug Administration (FDA) for the treatment of multiple cancers such as Non-squamous Cell Lung Cancer [
1]. There are some concerns on this class of ICIs about immune-related adverse events, including thyroid dysfunction, hypophysitis, adrenal insufficiency and autoimmune diabetes mellitus (DM) [
1]. …