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Published in: Comparative Clinical Pathology 6/2012

01-12-2012 | Original Article

Nitric oxide metabolites status in calves with acute and chronic diarrhea

Authors: G. A. Kojouri, H. Hassanpour, N. Taghavi, C. Taghadosi

Published in: Comparative Clinical Pathology | Issue 6/2012

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Abstract

Neonatal diarrhea in calves causes intestinal inflammation that can lead to an increase in the concentration of some inflammatory mediators like nitric oxide in serum. In the presence of some molecules in biological fluids, nitric oxide sustains a series of reactions and produces nitrate and nitrite. Consequently, this paper has been done to determine if the serum levels of nitrite and nitrate can be a precise yardstick to evaluate the health condition of calves. Sixty calves in three groups (20 heads healthy as control group, 20 heads with chronic diarrhea, and 20 heads with acute diarrhea) were considered, and blood samples were collected to determine the concentration of nitrite and nitrate in serum by reducing by cadmium and evaluation of photo-absorbance by spectrophotometer. Results showed that in calves with acute diarrhea, the total concentration of nitrite and nitrate and the concentration of nitrate were significantly more than healthy calves and the calves with chronic diarrhea (P < 0.001). In addition, a negative and significant correlation (r = −0.788, P value = 0.0353) was observed between nitrite and nitrate concentration of healthy calves.
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Metadata
Title
Nitric oxide metabolites status in calves with acute and chronic diarrhea
Authors
G. A. Kojouri
H. Hassanpour
N. Taghavi
C. Taghadosi
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Comparative Clinical Pathology / Issue 6/2012
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-011-1275-7

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