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Journal of Clinical Immunology
Published in: Journal of Clinical Immunology 1/2016

01-05-2016

Next Generation Sequencing Data Analysis in Primary Immunodeficiency Disorders – Future Directions

Authors: Mingyan Fang, Hassan Abolhassani, Che Kang Lim, Jianguo Zhang, Lennart Hammarström

Published in: Journal of Clinical Immunology | Special Issue 1/2016

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Abstract

Primary immunodeficiency diseases (PIDs) comprise a group of highly heterogeneous immune system diseases and around 300 forms of PID have been described to date. Next Generation Sequencing (NGS) has recently become an increasingly used approach for gene identification and molecular diagnosis of human diseases. Herein we summarize the practical considerations for the interpretation of NGS data and the techniques for searching disease-related PID genes, and suggest future directions for research in this field.
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Metadata
Title
Next Generation Sequencing Data Analysis in Primary Immunodeficiency Disorders – Future Directions
Authors
Mingyan Fang
Hassan Abolhassani
Che Kang Lim
Jianguo Zhang
Lennart Hammarström
Publication date
01-05-2016
Publisher
Springer US
Published in
Journal of Clinical Immunology / Issue Special Issue 1/2016
Print ISSN: 0271-9142
Electronic ISSN: 1573-2592
DOI
https://doi.org/10.1007/s10875-016-0260-y

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Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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