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Published in: BMC Pediatrics 1/2021

Open Access 01-12-2021 | Neonatal Necrotizing Enterocolitis | Research article

Early combined rehabilitation intervention to improve the short-term prognosis of premature infants

Authors: Yang Liu, Zheng-feng Li, Yun-huan Zhong, Zhi-hui Zhao, Wen-xin Deng, Ling-ling Chen, Bei-bei Liu, Tao-jun Du, Yong Zhang

Published in: BMC Pediatrics | Issue 1/2021

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Abstract

Background

To explore the clinical effect of early combined rehabilitation intervention on premature infants in the neonatal intensive care unit (NICU).

Methods

Premature infants with gestational ages less than 32 weeks or birth weights less than 1500 g were included in the present study.The participants were divided into the intervention group and control group. All infants received the current routine treatment based on the clinical guidelines, and the intervention group was additionally treated by visual and auditory stimulation, oral motor function, respiratory function and neurodevelopmental training. The following clinical outcomes were compared: durations of oxygen supplementation and indwelling gastric tube use; incidences of retinopathy of prematurity (ROP) and neonatal necrotizing enterocolitis (NEC); Sliverman scores; incidences of bronchopulmonary dysplasia (BPD) and intraventricular haemorrhage; days of hospitalization; and neurodevelopmental outcomes. Datas were analysed using the following statistical tests: the chi-square test, the independent samples or paired t test, repeated measures ANOVA, and the Wilcoxon rank sum test.

Results

Compared with those in the control group, premature infants in the intervention group had shorter durations of oxygen supplementation and indwelling gastric tube use, fewer hospitalization days and lower incidences of ROP, BPD, and NEC.The intervention group had lower Sliverman scores and higher Ballard neuromuscular scores than the control group.

Conclusion

Early combined rehabilitation intervention can improve the short-term clinical outcomes of premature infants.
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Metadata
Title
Early combined rehabilitation intervention to improve the short-term prognosis of premature infants
Authors
Yang Liu
Zheng-feng Li
Yun-huan Zhong
Zhi-hui Zhao
Wen-xin Deng
Ling-ling Chen
Bei-bei Liu
Tao-jun Du
Yong Zhang
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2021
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-021-02727-8

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