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Published in: Cardiovascular Diabetology 1/2015

Open Access 01-12-2015 | Original investigation

National trends in incidence and outcomes of abdominal aortic aneurysm among elderly type 2 diabetic and non-diabetic patients in Spain (2003–2012)

Authors: Ana Lopez-de-Andrés, Isabel Jiménez-Trujillo, Rodrigo Jiménez-García, Valentín Hernández-Barrera, José Mª de Miguel-Yanes, Manuel Méndez-Bailón, Napoleón Perez-Farinos, Miguel Ángel Salinero-Fort, Pilar Carrasco-Garrido

Published in: Cardiovascular Diabetology | Issue 1/2015

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Abstract

Background

This study aims to describe trends in the rate of abdominal aortic aneurysm (AAA) and use of open surgery repair (OSR) and endovascular aneurysm repair (EVAR) in elderly patients with and without type 2 diabetes in Spain, 2003–2012.

Methods

We select all patients with a discharge of AAA using national hospital discharge data. Discharges were grouped by diabetes status: type 2 diabetes and no diabetes. In both groups OSR and EVAR were identified. The incidence of discharges attributed to AAA were calculated overall and stratified by diabetes status and year. We calculated length of stay (LOHS) and in-hospital mortality (IHM). Use of OSR and EVAR were calculated stratified by diabetes status. Multivariate analysis was adjusted by age, sex, year, smoking habit and comorbidity.

Results

From 2003 to 2012, 115,020 discharges with AAA were identified. The mean age was 74.91 years and 16.7% suffered type 2 diabetes. Rates of discharges due to AAA increased significantly in diabetic patients (50.09 in 2003 to 78.23 cases per 100,000 in 2012) and non diabetic subjects (69.24 to 78.66). The incidences were higher among those without than those with diabetes in all the years studied.
The proportion of patients that underwent EVAR increased for both groups of patients and the open repair decreased. After multivariate analysis we found that LOHS and IHM have improved over the study period and diabetic patients had lower IHM than those without diabetes (OR 0.81; 95%CI 0.76-0.85).

Conclusions

Incidence rates were higher in non-diabetic patients. For diabetic and non diabetic patients the use of EVAR has increased and open repair seems to be decreasing. IHM and LOHS have improved from 2003 to 2012. Patients with diabetes had significantly lower mortality.
Literature
1.
go back to reference Lederle FA, Johnson GR, Wilson SE, Chute EP, Littooy FN, Bandyk D, et al. Prevalence and associations of abdominal aortic aneurysm detected through screening. Aneurysm Detection and Management (ADAM) Veterans Affairs Cooperative Study Group. Ann Intern Med. 1997;126:441–9.CrossRefPubMed Lederle FA, Johnson GR, Wilson SE, Chute EP, Littooy FN, Bandyk D, et al. Prevalence and associations of abdominal aortic aneurysm detected through screening. Aneurysm Detection and Management (ADAM) Veterans Affairs Cooperative Study Group. Ann Intern Med. 1997;126:441–9.CrossRefPubMed
2.
go back to reference Lederle FA, Johnson GR, Wilson SE, Chute EP, Hye RJ, Makaroun MS, et al. The aneurysm detection and management study screening program: validation cohort and final results. Aneurysm Detection and Management Veterans Affairs Cooperative Study Investigators. Arch Intern Med. 2000;160:1425–30.CrossRefPubMed Lederle FA, Johnson GR, Wilson SE, Chute EP, Hye RJ, Makaroun MS, et al. The aneurysm detection and management study screening program: validation cohort and final results. Aneurysm Detection and Management Veterans Affairs Cooperative Study Investigators. Arch Intern Med. 2000;160:1425–30.CrossRefPubMed
3.
go back to reference Kent KC, Zwolak RM, Egorova NN. Analysis of risk factors of abdominal aortic aneurysm in a cohort of more than 3 million individuals. J Vasc Surg. 2010;52:539–48.CrossRefPubMed Kent KC, Zwolak RM, Egorova NN. Analysis of risk factors of abdominal aortic aneurysm in a cohort of more than 3 million individuals. J Vasc Surg. 2010;52:539–48.CrossRefPubMed
4.
go back to reference Shah AD, Langenberg C, Rapsomaniki E, Denaxas S, Pujades-Rodriguez M, Gale CP, et al. Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1 · 9 million people. Lancet Diabetes Endocrinol. 2015;3:105–13.CrossRefPubMedPubMedCentral Shah AD, Langenberg C, Rapsomaniki E, Denaxas S, Pujades-Rodriguez M, Gale CP, et al. Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1 · 9 million people. Lancet Diabetes Endocrinol. 2015;3:105–13.CrossRefPubMedPubMedCentral
5.
go back to reference De Rango P, Farchioni L, Fiorucci B, Lenti M. Diabetes and abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2014;47:243–61.CrossRefPubMed De Rango P, Farchioni L, Fiorucci B, Lenti M. Diabetes and abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2014;47:243–61.CrossRefPubMed
6.
go back to reference Guirguis-Blake JM, Beil TL, Sun X, Senger CA, Whitlock EP. Primary care screening for abdominal aortic aneurysm: a systematic evidence review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US; 2014. Guirguis-Blake JM, Beil TL, Sun X, Senger CA, Whitlock EP. Primary care screening for abdominal aortic aneurysm: a systematic evidence review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US; 2014.
7.
go back to reference LeFevre ML, U.S. Preventive Services Task Force. Screening for abdominal aortic aneurysm: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2014;161:281–90.CrossRefPubMed LeFevre ML, U.S. Preventive Services Task Force. Screening for abdominal aortic aneurysm: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2014;161:281–90.CrossRefPubMed
8.
go back to reference Schermerhorn ML, O’Malley AJ, Jhaveri A, Cotterill P, Pomposelli F, Landon BE. Endovascular vs. open repair of abdominal aortic aneurysms in the Medicare population. N Engl J Med. 2008;358:464–74.CrossRefPubMed Schermerhorn ML, O’Malley AJ, Jhaveri A, Cotterill P, Pomposelli F, Landon BE. Endovascular vs. open repair of abdominal aortic aneurysms in the Medicare population. N Engl J Med. 2008;358:464–74.CrossRefPubMed
9.
go back to reference Markovic JN, Rajgor DD, Shortell CK. The impact of diabetes mellitus and renal insufficiency on the outcome of endovascular abdominal aortic aneurysm repair. Perspect Vasc Surg Endovasc Ther. 2010;22:235–44.CrossRefPubMed Markovic JN, Rajgor DD, Shortell CK. The impact of diabetes mellitus and renal insufficiency on the outcome of endovascular abdominal aortic aneurysm repair. Perspect Vasc Surg Endovasc Ther. 2010;22:235–44.CrossRefPubMed
10.
go back to reference Leurs LJ, Laheij RJ, Buth J. Influence of diabetes mellitus on the endovascular treatment of abdominal aortic aneurysms. J Endovasc Ther. 2005;12:288–96.CrossRefPubMed Leurs LJ, Laheij RJ, Buth J. Influence of diabetes mellitus on the endovascular treatment of abdominal aortic aneurysms. J Endovasc Ther. 2005;12:288–96.CrossRefPubMed
11.
go back to reference Katz DJ, Stanley JC, Zelenock GB. Operative mortality rates for intact and ruptured abdominal aortic aneurysms in Michigan: an eleven-year statewide experience. J Vasc Surg. 1994;19:804–15.CrossRefPubMed Katz DJ, Stanley JC, Zelenock GB. Operative mortality rates for intact and ruptured abdominal aortic aneurysms in Michigan: an eleven-year statewide experience. J Vasc Surg. 1994;19:804–15.CrossRefPubMed
12.
go back to reference Dardik A, Lin JW, Gordon TA, Williams GM, Perler BA. Results of elective abdominal aortic aneurysm repair in the 1990s: a population-based analysis of 2335 cases. J Vasc Surg. 1999;30:985–95.CrossRefPubMed Dardik A, Lin JW, Gordon TA, Williams GM, Perler BA. Results of elective abdominal aortic aneurysm repair in the 1990s: a population-based analysis of 2335 cases. J Vasc Surg. 1999;30:985–95.CrossRefPubMed
13.
go back to reference Hughes K, Jackson JD, Prendergast TI, Rose DA, Bolorunduro O, Obirieze A, et al. Diabetes mellitus is not associated with major morbidity following open abdominal aortic aneurysm repair. J Surg Res. 2013;184:751–4.CrossRefPubMed Hughes K, Jackson JD, Prendergast TI, Rose DA, Bolorunduro O, Obirieze A, et al. Diabetes mellitus is not associated with major morbidity following open abdominal aortic aneurysm repair. J Surg Res. 2013;184:751–4.CrossRefPubMed
14.
go back to reference Salcedo Jódar L, Alcázar Carmona P, Tenías Burillo JM, García Tejada R. Prevalence of abdominal aortic aneurysm in a rural population of 65–80 year-old males. Semergen. 2014;40:425–30.CrossRefPubMed Salcedo Jódar L, Alcázar Carmona P, Tenías Burillo JM, García Tejada R. Prevalence of abdominal aortic aneurysm in a rural population of 65–80 year-old males. Semergen. 2014;40:425–30.CrossRefPubMed
15.
go back to reference Gentille-Lorente DI, Salvadó-Usach T. Screening for abdominal aortic aneurysm by means of transthoracic echocardiography. Rev Esp Cardiol. 2011;64:395–400.CrossRefPubMed Gentille-Lorente DI, Salvadó-Usach T. Screening for abdominal aortic aneurysm by means of transthoracic echocardiography. Rev Esp Cardiol. 2011;64:395–400.CrossRefPubMed
16.
go back to reference Villar F, Pedro-Botet J, Vila R, Lahoz C. Aortic aneurysm. Clin Investig Arterioscler. 2013;25:224–30.CrossRefPubMed Villar F, Pedro-Botet J, Vila R, Lahoz C. Aortic aneurysm. Clin Investig Arterioscler. 2013;25:224–30.CrossRefPubMed
17.
go back to reference Sisó-Almirall A, Gilabert Solé R, Bru Saumell C, Kostov B, Mas Heredia M, González-de Paz L, et al. Feasibility of hand-held-ultrasonography in the screening of abdominal aortic aneurysms and abdominal aortic atherosclerosis. Med Clin (Barc). 2013;141(Sebastián Montal L):417–22.CrossRef Sisó-Almirall A, Gilabert Solé R, Bru Saumell C, Kostov B, Mas Heredia M, González-de Paz L, et al. Feasibility of hand-held-ultrasonography in the screening of abdominal aortic aneurysms and abdominal aortic atherosclerosis. Med Clin (Barc). 2013;141(Sebastián Montal L):417–22.CrossRef
18.
go back to reference Barba A, Vega De Céniga M, Estallo L, de la Fuente N, Viviens B, Izagirre M. Prevalence of abdominal aortic aneurysm is still high in certain areas of southern Europe. Ann Vasc Surg. 2013;27:1068–73.CrossRefPubMed Barba A, Vega De Céniga M, Estallo L, de la Fuente N, Viviens B, Izagirre M. Prevalence of abdominal aortic aneurysm is still high in certain areas of southern Europe. Ann Vasc Surg. 2013;27:1068–73.CrossRefPubMed
20.
go back to reference Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83.CrossRefPubMed Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83.CrossRefPubMed
21.
go back to reference Thomsen RW, Nielsen JS, Ulrichsen SP, Pedersen L, Hansen AM, Nilsson T. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: Collection of baseline data from the first 580 patients. Clin Epidemiol. 2012;4:43–8.CrossRefPubMedPubMedCentral Thomsen RW, Nielsen JS, Ulrichsen SP, Pedersen L, Hansen AM, Nilsson T. The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) study: Collection of baseline data from the first 580 patients. Clin Epidemiol. 2012;4:43–8.CrossRefPubMedPubMedCentral
23.
go back to reference Soriguer F, Goday A, Bosch-Comas A, Bordiú E, Calle-Pascual A, Carmena R, et al. Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study. Diabetologia. 2012;55:88–93.CrossRefPubMed Soriguer F, Goday A, Bosch-Comas A, Bordiú E, Calle-Pascual A, Carmena R, et al. Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study. Diabetologia. 2012;55:88–93.CrossRefPubMed
25.
go back to reference De Rango P, Cao P, Cieri E, Parlani G, Lenti M, Simonte G, et al. Comparison of surveillance vs. Aortic Endografting for Small Aneurysm Repair (CAESAR) investigators group. Effects of diabetes on small aortic aneurysms under surveillance according to a subgroup analysis from a randomized trial. J Vasc Surg. 2012;56:1555–63.CrossRefPubMed De Rango P, Cao P, Cieri E, Parlani G, Lenti M, Simonte G, et al. Comparison of surveillance vs. Aortic Endografting for Small Aneurysm Repair (CAESAR) investigators group. Effects of diabetes on small aortic aneurysms under surveillance according to a subgroup analysis from a randomized trial. J Vasc Surg. 2012;56:1555–63.CrossRefPubMed
26.
go back to reference Sensi L, Tedesco D, Mimmi S, Rucci P, Pisano E, Pedrini L, et al. Hospitalization rates and post-operative mortality for abdominal aortic aneurysm in Italy over the period 2000–2011. PLoS One. 2013;8:e83855.CrossRefPubMedPubMedCentral Sensi L, Tedesco D, Mimmi S, Rucci P, Pisano E, Pedrini L, et al. Hospitalization rates and post-operative mortality for abdominal aortic aneurysm in Italy over the period 2000–2011. PLoS One. 2013;8:e83855.CrossRefPubMedPubMedCentral
27.
go back to reference Mureebe L, Egorova N, Giacovelli JK, Gelijns A, Kent KC, McKinsey JF. National trends in the repair of ruptured abdominal aortic aneurysms. J Vasc Surg. 2008;48:1101–7.CrossRefPubMed Mureebe L, Egorova N, Giacovelli JK, Gelijns A, Kent KC, McKinsey JF. National trends in the repair of ruptured abdominal aortic aneurysms. J Vasc Surg. 2008;48:1101–7.CrossRefPubMed
28.
go back to reference Smelser DT, Tromp G, Elmore JR, Kuivaniemi H, Franklin DP, Kirchner HL, et al. Population risk factor estimates for abdominal aortic aneurysm from electronic medical records: a case control study. BMC Cardiovasc Disord. 2014;14:174.CrossRefPubMedPubMedCentral Smelser DT, Tromp G, Elmore JR, Kuivaniemi H, Franklin DP, Kirchner HL, et al. Population risk factor estimates for abdominal aortic aneurysm from electronic medical records: a case control study. BMC Cardiovasc Disord. 2014;14:174.CrossRefPubMedPubMedCentral
29.
go back to reference Baumgartner I, Hirsch AT, Abola MT, Cacoub PP, Poldermans D, Steg PG, et al. Cardiovascular risk profile and outcome of patients with abdominal aortic aneurysm in out-patients with atherothrombosis: data from the Reduction of Atherothrombosis for Continued Health (REACH) Registry. J Vasc Surg. 2008;48:808–14.CrossRefPubMed Baumgartner I, Hirsch AT, Abola MT, Cacoub PP, Poldermans D, Steg PG, et al. Cardiovascular risk profile and outcome of patients with abdominal aortic aneurysm in out-patients with atherothrombosis: data from the Reduction of Atherothrombosis for Continued Health (REACH) Registry. J Vasc Surg. 2008;48:808–14.CrossRefPubMed
30.
go back to reference Villard C, Swedenborg J, Eriksson P, Hultgren R. Reproductive history in women with abdominal aortic aneurysms. J Vasc Surg. 2011;54:341–5.CrossRefPubMed Villard C, Swedenborg J, Eriksson P, Hultgren R. Reproductive history in women with abdominal aortic aneurysms. J Vasc Surg. 2011;54:341–5.CrossRefPubMed
31.
go back to reference Vouyouka AG, Kent KC. Arterial vascular disease in women. J Vasc Surg. 2007;466:1295–302.CrossRef Vouyouka AG, Kent KC. Arterial vascular disease in women. J Vasc Surg. 2007;466:1295–302.CrossRef
32.
go back to reference Mureebe L, Egorova N, McKinsey JF, Kent KC. Gender trends in the repair of ruptured abdominal aortic aneurysms and outcomes. J Vasc Surg. 2010;51:9S–13.CrossRefPubMed Mureebe L, Egorova N, McKinsey JF, Kent KC. Gender trends in the repair of ruptured abdominal aortic aneurysms and outcomes. J Vasc Surg. 2010;51:9S–13.CrossRefPubMed
33.
go back to reference Thomas G, Khunti K, Curcin V, Molokhia M, Millett C, Majeed A, et al. Obesity paradox in people newly diagnosed with type 2 diabetes with and without prior cardiovascular disease. Diabetes Obes Metab. 2014;16:317–25.CrossRefPubMed Thomas G, Khunti K, Curcin V, Molokhia M, Millett C, Majeed A, et al. Obesity paradox in people newly diagnosed with type 2 diabetes with and without prior cardiovascular disease. Diabetes Obes Metab. 2014;16:317–25.CrossRefPubMed
34.
go back to reference Sidloff D, Stather P, Dattani N, Bown M, Thompson J, Sayers R, et al. Aneurysm global epidemiology study: public health measures can further reduce abdominal aortic aneurysm mortality. Circulation. 2014;129:747–53.CrossRefPubMed Sidloff D, Stather P, Dattani N, Bown M, Thompson J, Sayers R, et al. Aneurysm global epidemiology study: public health measures can further reduce abdominal aortic aneurysm mortality. Circulation. 2014;129:747–53.CrossRefPubMed
35.
go back to reference Jahangir E, Lipworth L, Edwards TL, Kabagambe EK, Mumma MT, Mensah GA, et al. Smoking, sex, risk factors and abdominal aortic aneurysms: a prospective study of 18782 persons aged above 65 years in the Southern Community Cohort Study. J Epidemiol Community Health. 2015:69:481–8. Jahangir E, Lipworth L, Edwards TL, Kabagambe EK, Mumma MT, Mensah GA, et al. Smoking, sex, risk factors and abdominal aortic aneurysms: a prospective study of 18782 persons aged above 65 years in the Southern Community Cohort Study. J Epidemiol Community Health. 2015:69:481–8.
36.
go back to reference Le MT, Jamrozik K, Davis TM, Norman PE. Negative association between infra-renal aortic diameter and glycaemia: the Health in Men Study. Eur J Vasc Endovasc Surg. 2007;33:599–604.CrossRefPubMed Le MT, Jamrozik K, Davis TM, Norman PE. Negative association between infra-renal aortic diameter and glycaemia: the Health in Men Study. Eur J Vasc Endovasc Surg. 2007;33:599–604.CrossRefPubMed
37.
go back to reference Miyama N, Dua MM, Yeung JJ, Schultz GM, Asagami T, Sho E, et al. Hyperglycemia limits experimental aortic aneurysm progression. J Vasc Surg. 2010;52:975–83.CrossRefPubMedPubMedCentral Miyama N, Dua MM, Yeung JJ, Schultz GM, Asagami T, Sho E, et al. Hyperglycemia limits experimental aortic aneurysm progression. J Vasc Surg. 2010;52:975–83.CrossRefPubMedPubMedCentral
38.
go back to reference Greenhalgh RM, Brown LC, Kwong GP, Powell JT, Thompson SG, EVAR trial participants. Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial. Lancet. 2004;364:843–8.CrossRefPubMed Greenhalgh RM, Brown LC, Kwong GP, Powell JT, Thompson SG, EVAR trial participants. Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial. Lancet. 2004;364:843–8.CrossRefPubMed
39.
go back to reference Lederle FA, Freischlag JA, Kyriakides TC, Padberg Jr FT, Matsumura JS, Kohler TR, et al. Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial. JAMA. 2009;302:1535–42.CrossRefPubMed Lederle FA, Freischlag JA, Kyriakides TC, Padberg Jr FT, Matsumura JS, Kohler TR, et al. Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial. JAMA. 2009;302:1535–42.CrossRefPubMed
40.
go back to reference Schermerhorn ML, Giles KA, Sachs T, Bensley RP, O’Malley AJ, Cotterill P, et al. Defining perioperative mortality after open and endovascular aortic aneurysm repair in the US Medicare population. J Am Coll Surg. 2011;212:349–55.CrossRefPubMedPubMedCentral Schermerhorn ML, Giles KA, Sachs T, Bensley RP, O’Malley AJ, Cotterill P, et al. Defining perioperative mortality after open and endovascular aortic aneurysm repair in the US Medicare population. J Am Coll Surg. 2011;212:349–55.CrossRefPubMedPubMedCentral
41.
go back to reference López-de-Andrés A, Martínez-Huedo MA, Carrasco-Garrido P, Hernández-Barrera V, Gil-de-Miguel A, Jiménez-García R. Trends in lower-extremity amputations in people with and without diabetes in Spain, 2001–2008. Diabetes Care. 2011;34:1570–6.CrossRefPubMedPubMedCentral López-de-Andrés A, Martínez-Huedo MA, Carrasco-Garrido P, Hernández-Barrera V, Gil-de-Miguel A, Jiménez-García R. Trends in lower-extremity amputations in people with and without diabetes in Spain, 2001–2008. Diabetes Care. 2011;34:1570–6.CrossRefPubMedPubMedCentral
42.
go back to reference Lopez-de-Andres A, Jimenez-García R, Hernandez-Barrera V, Perez-Farinos N, de Miguel-Yanes JM, Mendez-Bailon M, et al. National trends in utilization and outcomes of coronary revascularization procedures among people with and without type 2 diabetes in Spain (2001–2011). Cardiovasc Diabetol. 2014;13:3.CrossRefPubMedPubMedCentral Lopez-de-Andres A, Jimenez-García R, Hernandez-Barrera V, Perez-Farinos N, de Miguel-Yanes JM, Mendez-Bailon M, et al. National trends in utilization and outcomes of coronary revascularization procedures among people with and without type 2 diabetes in Spain (2001–2011). Cardiovasc Diabetol. 2014;13:3.CrossRefPubMedPubMedCentral
43.
go back to reference Ribera A, Marsal JR, Ferreira-González I, Cascant P, Pons JM, Mitjavila F, et al. Predicting in-hospital mortality with coronary bypass surgery using hospital discharge data: comparison with a prospective observational study. Rev Esp Cardiol. 2008;61:843–52.CrossRefPubMed Ribera A, Marsal JR, Ferreira-González I, Cascant P, Pons JM, Mitjavila F, et al. Predicting in-hospital mortality with coronary bypass surgery using hospital discharge data: comparison with a prospective observational study. Rev Esp Cardiol. 2008;61:843–52.CrossRefPubMed
Metadata
Title
National trends in incidence and outcomes of abdominal aortic aneurysm among elderly type 2 diabetic and non-diabetic patients in Spain (2003–2012)
Authors
Ana Lopez-de-Andrés
Isabel Jiménez-Trujillo
Rodrigo Jiménez-García
Valentín Hernández-Barrera
José Mª de Miguel-Yanes
Manuel Méndez-Bailón
Napoleón Perez-Farinos
Miguel Ángel Salinero-Fort
Pilar Carrasco-Garrido
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Cardiovascular Diabetology / Issue 1/2015
Electronic ISSN: 1475-2840
DOI
https://doi.org/10.1186/s12933-015-0216-1

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