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Current Dermatology Reports
Published in: Current Dermatology Reports 4/2016

01-12-2016 | Wound Care and Healing (A Friedman, Section Editor)

Nanomaterials for Wound Healing

Authors: Breanne Mordorski, Tarl Prow

Published in: Current Dermatology Reports | Issue 4/2016

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Abstract

Purpose of Review

Despite the emergence of various new wound care products, millions of people continue to suffer from complications associated with acute and chronic wounds. Nanomaterials offer a variety of strategies to accelerate wound closure and promote appropriate progression through the stages of healing, which will be detailed in this review.

Recent Findings

The small size of nanomaterials enhances penetration and permeation of tissues and lends a large surface area-to-volume ratio, ideal for topical drug delivery. Furthermore, nanofibers may be utilized to create nanoscaffold wound dressings that simulate the topographic appearance of endogenous extracellular matrix, thereby stimulating wound reepithelialization and collagen production.

Summary

Together, nanomaterials offer many approaches to reduce the morbidity associated with acute and chronic wounds, as demonstrated by a substantial body of pre-clinical data. Future investigations should aim to address the paucity of human clinical trial data, essential for translating wound-healing benefits from bench to bedside.
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Metadata
Title
Nanomaterials for Wound Healing
Authors
Breanne Mordorski
Tarl Prow
Publication date
01-12-2016
Publisher
Springer US
Published in
Current Dermatology Reports / Issue 4/2016
Electronic ISSN: 2162-4933
DOI
https://doi.org/10.1007/s13671-016-0159-0

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