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Journal of Cardiovascular Translational Research
Published in: Journal of Cardiovascular Translational Research 1/2020

01-02-2020 | Myocardial Infarction | Original Article

Gender-Specific Predictive Markers of Poor Prognosis for Patients with Acute Myocardial Infarction During a 6-Month Follow-up

Authors: Ping Wang, Jianhua Yao, Yuan Xie, Ming Luo

Published in: Journal of Cardiovascular Translational Research | Issue 1/2020

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Abstract

Mounting evidence indicates the impact of gender difference on the assessment, treatment, and outcome of patients with acute myocardial infarction (AMI). However, gender-specific prognostic markers of AMI are still lacking. The present study aimed to investigate gender-specific markers of poor prognosis (all-cause mortality or readmission) in a cohort of AMI patients followed up for 6 months. Compared with males (n = 157), females (n = 40) were older and more frequent with previous medical history of hypertension and diabetes mellitus. During the 6-month follow-up, BUN ≥ 7.73 mM, myoglobin ≥ 705.8 ng/mL, and Killip classification 2–4 were identified as the independent predictors of poor prognosis for male AMI patients, while D-dimer ≥ 0.43 mg/L as an independent predictor of poor prognosis in female AMI patients. In conclusion, our data suggest that prognostic markers for AMI patients may differ according to genders. Gender-specific prognostic markers may be useful to guide the risk stratification, clinical therapy, and medications for AMI patients.
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Metadata
Title
Gender-Specific Predictive Markers of Poor Prognosis for Patients with Acute Myocardial Infarction During a 6-Month Follow-up
Authors
Ping Wang
Jianhua Yao
Yuan Xie
Ming Luo
Publication date
01-02-2020
Publisher
Springer US
Published in
Journal of Cardiovascular Translational Research / Issue 1/2020
Print ISSN: 1937-5387
Electronic ISSN: 1937-5395
DOI
https://doi.org/10.1007/s12265-019-09946-6

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