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Published in: Pediatric Cardiology 5/2003

01-09-2003 | Case Report

Myocardial Cell Damage in Duchenne Muscular Dystrophy

Authors: C. Ramaciotti, S. T. Iannaccone, W. A. Scott

Published in: Pediatric Cardiology | Issue 5/2003

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Abstract

We report two cases of Duchenne muscular dystrophy that presented with laboratory evidence of acute transient myocardial cell damage. The mechanism for development of cardiomyopathy associated with Duchenne muscular dystrophy is not well understood, and this report raises the possibility that the progressive deterioration of cardiac function is punctuated by acute episodes of cell damage.
Literature
1.
go back to reference Annane, D, Merlet, P, Radvanyi, H, et al. 1996Blunted coronary reserve in myotonic dystrophy. An early and gene-related phenomenon.Circulation94973977PubMed Annane, D, Merlet, P, Radvanyi, H,  et al. 1996Blunted coronary reserve in myotonic dystrophy. An early and gene-related phenomenon.Circulation94973977PubMed
2.
go back to reference Beltrami, AP, Urbanek, K, Kajstura, J, et al. 2001Evidence that human cardiac myocytes divide after myocardial infarction.N Engl J Med34417501757PubMed Beltrami, AP, Urbanek, K, Kajstura, J,  et al. 2001Evidence that human cardiac myocytes divide after myocardial infarction.N Engl J Med34417501757PubMed
3.
go back to reference Carlson, CG 1998The dystrophinopathies: an alternative to the structural hypothesis.Neurobiol Dis5315CrossRefPubMed Carlson, CG 1998The dystrophinopathies: an alternative to the structural hypothesis.Neurobiol Dis5315CrossRefPubMed
4.
go back to reference Coral-Vazquez, R, Cohn, RD, Moore, SA, et al. 1999Disruption of the sarcoglycan–sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy.Cell98465474PubMed Coral-Vazquez, R, Cohn, RD, Moore, SA,  et al. 1999Disruption of the sarcoglycan–sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy.Cell98465474PubMed
5.
go back to reference Engel, AG, Yamamoto, M, Fishbeck, KH 1994Dystrophinopathies.Engel, AGFranzini-Armstrong, . eds. Myology: Basic and ClinicalMcGraw-HillNew York11331187 Engel, AG, Yamamoto, M, Fishbeck, KH 1994Dystrophinopathies.Engel, AGFranzini-Armstrong, . eds. Myology: Basic and ClinicalMcGraw-HillNew York11331187
6.
go back to reference Gnecchi-Ruscone, T, Taylor, J, Mercuri, E, et al. 1999Cardiomyopathy in Duchenne, Becker, and sarcoglycanopathies: a role for coronary dysfunction?Muscle Nerve2215491556CrossRefPubMed Gnecchi-Ruscone, T, Taylor, J, Mercuri, E,  et al. 1999Cardiomyopathy in Duchenne, Becker, and sarcoglycanopathies: a role for coronary dysfunction?Muscle Nerve2215491556CrossRefPubMed
7.
go back to reference Hammerer-Leercher, A, Erlacher, P, Bittner, R, et al. 2001Clinical and experimental results on cardiac troponin expression in Duchenne muscular dystrophy.Clin Chem47451458PubMed Hammerer-Leercher, A, Erlacher, P, Bittner, R,  et al. 2001Clinical and experimental results on cardiac troponin expression in Duchenne muscular dystrophy.Clin Chem47451458PubMed
8.
go back to reference Hays, AP, Armbrustmacher, . 1999Skeletal muscle.Rubin, EFarber, JL eds. PathologyLippincott–RavenPhiladelphia14141440 Hays, AP, Armbrustmacher, . 1999Skeletal muscle.Rubin, EFarber, JL eds. PathologyLippincott–RavenPhiladelphia14141440
9.
go back to reference Ishikawa, Y, Bach, JR, Minami, R 1999Cardioprotection for Duchenne’s muscular dystrophy.Am Heart J37895902 Ishikawa, Y, Bach, JR, Minami, R 1999Cardioprotection for Duchenne’s muscular dystrophy.Am Heart J37895902
10.
go back to reference Nigro, G, Comi, LI, Politano, L, Bain, RJI 1990The incidence and evolution of cardiomyopathy in Duchenne muscular dystrophy.Int J Cardiol26271277PubMed Nigro, G, Comi, LI, Politano, L, Bain, RJI 1990The incidence and evolution of cardiomyopathy in Duchenne muscular dystrophy.Int J Cardiol26271277PubMed
11.
go back to reference Quaini, F, Urbanek, K, Beltrami, AP, et al. 2002Chimerism of the transplanted heart.N Engl J Med346515PubMed Quaini, F, Urbanek, K, Beltrami, AP,  et al. 2002Chimerism of the transplanted heart.N Engl J Med346515PubMed
12.
go back to reference Sander, M, Chavoshan, B, Harris, SA, et al. 2000Functional muscle ischemia in neuronal nitric oxide synthase–deficient skeletal muscle of children with Duchenne muscular dystrophy.Proc Natl Acad Sci USA971381813823CrossRefPubMed Sander, M, Chavoshan, B, Harris, SA,  et al. 2000Functional muscle ischemia in neuronal nitric oxide synthase–deficient skeletal muscle of children with Duchenne muscular dystrophy.Proc Natl Acad Sci USA971381813823CrossRefPubMed
Metadata
Title
Myocardial Cell Damage in Duchenne Muscular Dystrophy
Authors
C. Ramaciotti
S. T. Iannaccone
W. A. Scott
Publication date
01-09-2003
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 5/2003
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-002-0408-9

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