Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Annals of Hematology
Published in: Annals of Hematology 4/2020

01-04-2020 | Myelodysplastic Syndrome | Letter to the Editor

Clone wars: co-occurrence of IDH2 R140Q and R172K in myelodysplastic syndromes

Authors: Valentina Rosso, Jessica Petiti, Matteo Dragani, Giacomo Andreani, Eleonora Croce, Marco Lo Iacono, Giuseppe Saglio, Carmen Fava, Daniela Cilloni

Published in: Annals of Hematology | Issue 4/2020

Login to get access

Excerpt

Dear Editor, …
Literature
1.
Savona MR, Malcovati L, Komrokji R, Tiu RV, Mughal TI, Orazi A, Kiladjian JJ, Padron E, Solary E, Tibes R, Itzykson R, Cazzola M, Mesa R, Maciejewski J, Fenaux P, Garcia-Manero G, Gerds A, Sanz G, Niemeyer CM, Cervantes F, Germing U, Cross NC, List AF, Group MMIW (2015) An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults. Blood 125(12):1857–1865. https://​doi.​org/​10.​1182/​blood-2014-10-607341 CrossRefPubMedPubMedCentral
2.
Malcovati L, Hellström-Lindberg E, Bowen D, Adès L, Cermak J, del Cañizo C, Della Porta MG, Fenaux P, Gattermann N, Germing U, Jansen JH, Mittelman M, Mufti G, Platzbecker U, Sanz GF, Selleslag D, Skov-Holm M, Stauder R, Symeonidis A, van de Loosdrecht AA, de Witte T, Cazzola M (2013) Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet. Blood 122(17):2943–2964
3.
Lindsley RC, Ebert BL (2013) Molecular pathophysiology of myelodysplastic syndromes. Annu Rev Pathol 8(1):21–47
4.
Pellagatti A, Boultwood J (2015) The molecular pathogenesis of the myelodysplastic syndromes. Eur J Haematol 95(1):3–15
5.
Dalle IA, DiNardo CD (2018) The role of enasidenib in the treatment of mutant IDH2 acute myeloid leukemia. Ther Adv Hematol 9(7):163–173
6.
DiNardo CD, Jabbour E, Ravandi F, Takahashi K, Daver N, Routbort M, Patel KP, Brandt M, Pierce S, Kantarjian H, Garcia-Manero G (2016) IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression. Leukemia 30(4):980–984
Metadata
Title
Clone wars: co-occurrence of IDH2 R140Q and R172K in myelodysplastic syndromes
Authors
Valentina Rosso
Jessica Petiti
Matteo Dragani
Giacomo Andreani
Eleonora Croce
Marco Lo Iacono
Giuseppe Saglio
Carmen Fava
Daniela Cilloni
Publication date
01-04-2020
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 4/2020
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-020-03913-x

Other articles of this Issue 4/2020

Annals of Hematology 4/2020 Go to the issue

Original Article

Genetic polymorphisms of HbE/beta thalassemia related to clinical presentation: implications for clinical diversity

Original Article

Prevalence of pulmonary hypertension in myelofibrosis

Original Article

High leukemia-free survival after TBI-based conditioning and mycophenolate mofetil-containing immunosuppression in patients allografted for chronic myelomonocytic leukemia: a single-center experience

Original Article

Successful sirolimus treatment of patients with pure red cell aplasia complicated with renal insufficiency

Letter to the Editor

Less ‘reds’ more ‘blues’: hemoglobin level and depression in non-transfusion-dependent thalassemia

Original Article

Comparison of two different anti-infectious approaches after high-dose chemotherapy and autologous stem cell transplantation for hematologic malignancies in a 12-year period in British Hospital, Uruguay
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits