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Journal of Cardiothoracic Surgery

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Open Access 01-12-2023 | Myasthenia Gravis | Case Report

Unexpected fibrous mediastinitis in a patient with myasthenia gravis - a case report

Authors: Xuyang Wang, Xiaoping Zuo, Fuqiang Wang, Yun Wang

Published in: Journal of Cardiothoracic Surgery | Issue 1/2023

Abstract

Background

Fibrous mediastinitis (FM) is a rare mediastinal lesion characterized by proliferation of fibrous tissue within the mediastinum. Previous reports have shown that this lesion can be caused by histoplasmosis and tuberculosis. In extremely rare cases, FM can also be caused by autoimmune diseases such as antineutrophil cytoplasmic antibody-associated vasculitis and large-vessel arteritis.

Case presentation

In our case, we report unexpected fibrous mediastinitis found after robotic thymectomy in a patient with myasthenia gravis (MG). The preoperative imaging indicated no obvious lesion in the mediastinum and the patient denied histories of both histoplasmosis and tuberculosis. After the operation, both proliferation of fibrous tissue and ectopic germinal centres (GCs) could be found in the thymus.

Conclusion

This rare case might enrich our knowledge of the relationship between FM and autoimmune diseases.

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Title: Unexpected fibrous mediastinitis in a patient with myasthenia gravis - a case report
Authors: Xuyang Wang
Xiaoping Zuo
Fuqiang Wang
Yun Wang
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Myasthenia Gravis
Mediastinitis
Mediastinitis
Thymectomy
Thymectomy
Tuberculosis
Tuberculosis
Histoplasmosis
Published in: Journal of Cardiothoracic Surgery / Issue 1/2023
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-023-02417-9

2024 ASCO Annual Meeting

Springer Medicine

Unexpected fibrous mediastinitis in a patient with myasthenia gravis - a case report

Abstract

Background

Case presentation

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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