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01-11-2020 | Multiple Sclerosis | Original Article

Italian validation of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ)

Authors: Andrea Tacchino, Michela Ponzio, Ludovico Pedullà, Jessica Podda, Margherita Monti Bragadin, Elisabetta Pedrazzoli, Giovanna Konrad, Mario Alberto Battaglia, Lidwine Mokkink, Giampaolo Brichetto

Published in: Neurological Sciences | Issue 11/2020

Abstract

Introduction

Arm and hand function deficits are commonly in people with multiple sclerosis (PwMS). The Arm Function in Multiple Sclerosis Questionnaire (AMSQ) is a novel self-administered instrument specifically developed to evaluate upper limb function in MS. The aim of this study was to translate and adapt the AMSQ into Italian and to assess its psychometric properties in PwMS. Validity (structural, construct, and known-groups) and reliability (internal consistency, test-retest, and measurement error) were assessed.

Materials and methods

From June 2017 to February 2018, a prospective cohort of PwMS among those followed as outpatients at the Rehabilitation Services of the Italian Multiple Sclerosis Society (AISM) of Genoa, Padua, and Vicenza was involved in the study. Construct validity of AMSQ was determined by examining correlations with the Italian version of ABILHAND, Modified Fatigue Impact Scale (MFIS), and Functional Independence Measure (FIM).

Results

A total of 234 PwMS were enrolled. The mean AMSQ total score was 67.3 (SD = 38.4). Factor analysis results suggested one factor. As expected, moderate to high correlation coefficients were found between AMSQ and ABILHAND (− 0.79), MFIS (0.50) and its subsets, and FIM (− 0.60) and its subsets involving upper limb functioning. PwMS with higher EDSS reported worse total score of AMSQ than patients with low disability. The internal consistency of the 31 items was high (Cronbach’s α, 0.98). Test-retest reliability, as measured with ICC, was 0.96 (95% IC, 0.93–0.98), and measurement error was about 8.3 points showing good reliability.

Discussion

AMSQ has been adapted and validated, it is a reliable questionnaire for Italian PwMS.

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Title: Italian validation of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ)
Authors: Andrea Tacchino
Michela Ponzio
Ludovico Pedullà
Jessica Podda
Margherita Monti Bragadin
Elisabetta Pedrazzoli
Giovanna Konrad
Mario Alberto Battaglia
Lidwine Mokkink
Giampaolo Brichetto
Publication date: 01-11-2020
Publisher: Springer International Publishing
Keyword: Multiple Sclerosis
Published in: Neurological Sciences / Issue 11/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04363-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Italian validation of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ)

Abstract

Introduction

Materials and methods

Results

Discussion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Materials and methods

Results

Discussion

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