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Published in: Abdominal Radiology 6/2010

01-12-2010

Multiple pancreatic insulinomas: multislice CT

Authors: Lina Menassa-Moussa, Georges Halaby, Chadi Braidy

Published in: Abdominal Radiology | Issue 6/2010

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Abstract

Imaging techniques are in permanent evolution and so are their respective sensitivities. We present a case of a patient who had three abdominal CT scans over 10 years for the detection of pancreatic insulinomas. The first was made on an incremental CT and showed no lesion, the second on a single-slice helical CT which revealed a single centimetric tumor of the head of the pancreas, and the third on 64-slice CT which revealed 5 infracentimetric tumors. We do not know if all were present at the first scan but it is possible that these small tumors could have been missed on thick CT scan slices with overlap. The ideal imaging technique for the detection of endocrine pancreatic tumor is not known yet. The detection rates in the latest publications are 80% for CT scans and 70% for MRI, but there is a slight preference for CT scan because of its larger availability and higher resolution.
Literature
1.
go back to reference Noone TC, Hosey J, Firat Z, et al. (2005) Imaging and localization of islet-cell tumours of the pancreas on CT and MRI. Best Pract Res Clin Endocrinol Metab 19:195–211CrossRefPubMed Noone TC, Hosey J, Firat Z, et al. (2005) Imaging and localization of islet-cell tumours of the pancreas on CT and MRI. Best Pract Res Clin Endocrinol Metab 19:195–211CrossRefPubMed
2.
go back to reference Sheth S, Fishman E (2002) Imaging of uncommon tumors of the pancreas. Radiol Clin North Am 40:1273–1287CrossRefPubMed Sheth S, Fishman E (2002) Imaging of uncommon tumors of the pancreas. Radiol Clin North Am 40:1273–1287CrossRefPubMed
3.
go back to reference Balci NC, Semelka RC (2001) Radiologic features of cystic, endocrine and other pancreatic neoplasms. EJR 38:113–119CrossRef Balci NC, Semelka RC (2001) Radiologic features of cystic, endocrine and other pancreatic neoplasms. EJR 38:113–119CrossRef
4.
go back to reference Power N, Reznek RH (2002) Imaging pancreatic islet cell tumors. Imaging 14:147–159 Power N, Reznek RH (2002) Imaging pancreatic islet cell tumors. Imaging 14:147–159
5.
go back to reference Chatziioannou A, Kehagias D, Mourikis D, et al. (2001) Imaging and localization of pancreatic insulinomas. Clin Imaging 25:275–283CrossRefPubMed Chatziioannou A, Kehagias D, Mourikis D, et al. (2001) Imaging and localization of pancreatic insulinomas. Clin Imaging 25:275–283CrossRefPubMed
6.
go back to reference Sheth S, Hruban RK, Fishman EK (2002) Helical CT of islet cell tumors of the pancreas: typical and atypical manifestations. AJR 179:725–730PubMed Sheth S, Hruban RK, Fishman EK (2002) Helical CT of islet cell tumors of the pancreas: typical and atypical manifestations. AJR 179:725–730PubMed
7.
go back to reference Nikfarjam M, Warshaw AL, Axelrod L, et al. (2008) Improved contemporary surgical management of insulinomas: a 25-year experience at the Massachusetts General Hospital. Ann Surg 247:165–172CrossRefPubMed Nikfarjam M, Warshaw AL, Axelrod L, et al. (2008) Improved contemporary surgical management of insulinomas: a 25-year experience at the Massachusetts General Hospital. Ann Surg 247:165–172CrossRefPubMed
8.
go back to reference King AD, Ko G, Yeung V, et al. (1998) Dual phase spiral CT in the detection of small insulinomas of the pancreas. BJR 71:20–23PubMed King AD, Ko G, Yeung V, et al. (1998) Dual phase spiral CT in the detection of small insulinomas of the pancreas. BJR 71:20–23PubMed
9.
go back to reference Fiddler JL, Fletcher JG, Reading CC, et al. (2003) Preoperative detection of pancreatic insulinomas on multiphasic helical CT. AJR 181:775–780 Fiddler JL, Fletcher JG, Reading CC, et al. (2003) Preoperative detection of pancreatic insulinomas on multiphasic helical CT. AJR 181:775–780
10.
go back to reference Gouya H, Vignaux O, Augui J, et al. (2003) CT, endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas. AJR 181:987–992PubMed Gouya H, Vignaux O, Augui J, et al. (2003) CT, endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas. AJR 181:987–992PubMed
11.
go back to reference Thoeni RF, Mueller-Lisse UG, Chan R, et al. (2000) Detection of small functional islet cell tumors in the pancreas: selection of MR sequences of optimal sensitivity. Radiology 214:483–490PubMed Thoeni RF, Mueller-Lisse UG, Chan R, et al. (2000) Detection of small functional islet cell tumors in the pancreas: selection of MR sequences of optimal sensitivity. Radiology 214:483–490PubMed
12.
go back to reference Ichikawa T, Peterson MS, Federal MP, et al. (2000) Islet cell tumor of the pancreas: biphasic CT versus MR imaging in tumor detection. Radiology 216:163–171PubMed Ichikawa T, Peterson MS, Federal MP, et al. (2000) Islet cell tumor of the pancreas: biphasic CT versus MR imaging in tumor detection. Radiology 216:163–171PubMed
Metadata
Title
Multiple pancreatic insulinomas: multislice CT
Authors
Lina Menassa-Moussa
Georges Halaby
Chadi Braidy
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 6/2010
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-009-9585-9

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