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Archives of Virology
Published in: Archives of Virology 9/2008

01-09-2008 | Brief Report

Multiple interspecies recombination events within RNA2 of Grapevine fanleaf virus and Arabis mosaic virus

Authors: E. Vigne, A. Marmonier, M. Fuchs

Published in: Archives of Virology | Issue 9/2008

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Abstract

Sequence alignments and SISCAN analyses inferred multiple interspecies recombination events within RNA2 of strains GHu of Grapevine fanleaf virus (GFLV) and Ta of Arabis mosaic virus (ArMV), two closely related subgroup A nepoviruses in the family Comoviridae. Interspecies recombination events were identified in the 5′ untranslated region, the putative homing protein and movement protein genes but not in the coat protein gene and 3′ untranslated region. These findings suggest a dynamic relationship between GFLV and ArMV, and a differential selection pressure on RNA2-encoded proteins with constraints in terms of function and co-adaptation that limit interspecies recombination to certain gene segments.
Literature
1.
Andret-Link P, Laporte C, Valat L, Laval L, Ritzenthaler C, Demangeat G, Vigne E, Pfeiffer P, Stussi-Garaud C, Fuchs M (2004) Grapevine fanleaf virus: still a major threat to the grapevine industry. J Plant Pathol 86:183–195
2.
Andret-Link P, Schmitt-Keichinger C, Demangeat G, Komar V, Fuchs M (2004) The specific transmission of Grapevine fanleaf virus by its nematode vector Xiphinema index is solely determined by the viral coat protein. Virology 320:12–22PubMedCrossRef
3.
Belin C, Schmitt C, Gaire F, Walter B, Demangeat G, Pinck L (1999) The nine C-terminal residues of the Grapevine fanleaf nepovirus movement protein are critical for systemic virus spread. J Gen Virol 80:1347–1356PubMed
4.
Belin C, Schmitt C, Demangeat G, Komar V, Pinck L, Fuchs M (2001) Involvement of RNA2-encoded proteins in the specific transmission of Grapevine fanleaf virus by its nematode vector Xiphinema index. Virology 291:161–171PubMedCrossRef
5.
Bovey R, Gärtel W, Hewitt WP, Martelli GP, Vuittenez A (1980) The most important virus diseases of grapevine. In: Bovey R, Gärtel W, Hewitt WP, Martelli GP, Vuittenez A (eds) Virus and virus-like diseases of grapevines. Editions Payot, Lausanne, pp 46–56
6.
Escriu F, Fraile A, Garcia-Arenal F (2007) Constraints to genetic exchange support gene coadaptation in a tripartite RNA virus. PLoS Pathogens 3:e8PubMedCrossRef
7.
Garcia-Arenal F, Fraile A, Malpica JM (2001) Variability and genetic structure of plant virus populations. Annu Rev Phytopathol 39:157–186PubMedCrossRef
8.
Gibbs MJ, Armstrong JS, Gibbs AJ (2000) Sister-scanning: a monte carlo procedure for assessing signals in recombinant sequences. Bioinformatics 16:573–582PubMedCrossRef
9.
Huss B, Walter B, Fuchs M (1989) Cross-protection between Arabis mosaic virus and Grapevine fanleaf virus in Chenopodium quinoa. Ann appl Biol 114:45–60CrossRef
10.
Le Gall O, Candresse T, Dunez J (1995) Transfer of the 3′ non-translated region of grapevine chrome mosaic virus RNA-1 by recombination to tomato black ring virus RNA-2 in pseudorecombinant isolates. J Gen Virol 76:1285–1289PubMedCrossRef
11.
Le Gall O, Lanneau M, Candresse T, Dunez J (1995) The nucleotide sequence of the RNA-2 of an isolate of the English serotype of tomato black ring virus: RNA recombination in the history of nepoviruses. J Gen Virol 76:1279–1283PubMedCrossRef
12.
Le Gall O, Sanfaçon H, Ikegami M, Iwanami T, Jones T, Karasev A, Lehto K, Wellink J, Wetzel T, Yoshikawa N (2007) Cheravirus and Sadwavirus: two unassigned genera of plant positive-sense single-stranded RNA viruses formerly considered atypical members of the genus Nepovirus (family Comoviridae). Arch Virol 159:1767–1774CrossRef
13.
Legin R, Bass P, Etienne L, Fuchs M (1993) Selection of mild virus strains of fanleaf degeneration by comparative field performance of infected grapevines. Vitis 32:103–110
14.
Loudes AM, Ritzenthaler C, Pinck M, Serghini MA, Pinck L (1995) The 119 kDa and 124 kDa polyproteins of Arabis mosaic nepovirus (isolate S) are encoded by two distinct RNA2 species. J Gen Virol 76:899–906PubMedCrossRef
15.
Martin DP, van der Walt E, Posada D, Rybicki EP (2005) The evolutionary value of recombination is constrained by genome modularity. PLoS Genetics 4:e51
16.
Mayo MA, Robinson DJ (1996) Nepoviruses: molecular biology and replication. In: Harrison BD, Murant AF (eds) The plant viruses, polyhedral virions and bipartite RNA. Plenum, New York, pp 139–185
17.
Mushegian AR (1994) The putative movement domain encoded by nepovirus RNA2 is conserved in all sequenced nepoviruses. Arch Virol 135:437–441PubMedCrossRef
18.
Ohshima K, Tomitaka Y, Wood JT, Minematsu Y, Kajiyama H, Tomimura K, Gibbs AJ (2007) Patterns of recombination in turnip mosaic virus genomic sequences indicate hotspots of recombination. J Gen Virol 88:298–315PubMedCrossRef
19.
Pompe-Novak M, Gutiérrez-Aguirre I, Vojvoda J, Blas M, Tomazic I, Vigne E, Fuchs M, Ravnikar M, Petrovic N (2007) Genetic variability within the RNA2 of Grapevine fanleaf virus. Eur J Plant Pathol 117:307–312CrossRef
20.
Saitou N, Nei M (1987) The neighbour-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406–425PubMed
21.
Serghini M, Fuchs M, Pinck M, Reinbolt J, Walter B, Pinck L (1990) RNA2 of Grapevine fanleaf virus: sequence analysis and coat protein cistron location. J. Gen Virol 71:1433–1441PubMedCrossRef
22.
Shapka N, Nagy PD (2004) The AU-rich RNA recombination hot spot sequence of Brome mosaic virus is functional in Tombusviruses: implications for the mechanism of RNA recombination. J Virol 78:2288–2300PubMedCrossRef
23.
Simmonds P (2006) Recombination and selection in the evolution of picornaviruses and other mammalian positive-stranded RNA viruses. J Virol 80:11124–11140PubMedCrossRef
24.
Thompson JD, Higgins DJ, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673–4680PubMedCrossRef
25.
Vigne E, Bergdoll M, Guyader S, Fuchs M (2004) Population structure and genetic variability within isolates of Grapevine fanleaf virus from a naturally infected vineyard in France: evidence for mixed infection and recombination. J Gen Virol 85:2435–2445PubMedCrossRef
26.
Vigne E, Demangeat G, Komar V, Fuchs M (2005) Characterization of a naturally occurring Grapevine fanleaf virus recombinant isolate. Arch Virol 150:2241–2255PubMedCrossRef
27.
Vives MC, Rubio L, Sambade A, Mirkov TE, Moreno P, Guerri J (2005) Evidence of multiple recombination events between two RNA sequence variants within a Citrus tristeza virus isolate. Virology 331:232–237PubMedCrossRef
28.
Wetzel T, Meunier L, Jaeger U, Reustle GM, Krczal G (2001) Complete nucleotide sequences of the RNAs 2 of German isolates of Grapevine fanleaf and Arabis mosaic nepoviruses. Virus Res 75:139–145PubMedCrossRef
29.
Wetzel T, Fuchs M, Bobko M, Krczal G (2002) Size and sequence variability of the Arabis mosaic virus protein 2A. Arch Virol 147:1643–1653PubMedCrossRef
30.
Worobey M, Holmes EC (1999) Evolutionary aspects of recombination in RNA viruses. J Gen Virol 80:2535–2543PubMed
31.
Zhang C, Gu H, Ghabrial SA (2007) Molecular characterization of naturally occurring RNA1 recombinants of the comovirus Bean pod mottle virus. Phytopathol 97:1255–1262CrossRef
Metadata
Title
Multiple interspecies recombination events within RNA2 of Grapevine fanleaf virus and Arabis mosaic virus
Authors
E. Vigne
A. Marmonier
M. Fuchs
Publication date
01-09-2008
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 9/2008
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-008-0182-y

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