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01-04-2012

Multiple hepatocellular adenomas in a patient with glycogen storage disease type I: various enhancement patterns in MRI with Gd-EOB-DTPA

Authors: Ayami Sakamoto, Hideyuki Hayashi, Ichiro Sakamoto, Ichiro Isomoto, Susumu Eguchi, Mitsuhisa Takatsuki, Tatsuki Ichikawa, Kuniko Abe, Tomayoshi Hayashi, Masataka Uetani

Published in: Abdominal Radiology | Issue 2/2012

Abstract

The patient is a 20-year-old man with glycogen storage disease type I (GSD-type I). In his teens, multiple focal hepatic masses were detected on abdominal ultrasonography (US), which were diagnosed as multiple hepatocellular adenomas from the imaging. During follow-up, these masses had shown intermittent growth in size. In the evaluation of Gd-EOB-DTPA (gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid) MR imaging, these masses showed various signal intensities from hypo- to hyperintense during the hepatocyte-specific phase. Intermittent growth and elevation of serum PIVKA-II levels indicate the potential for malignant transformation, so the patient underwent partial hepatectomy. The resected masses were all consistent with benign hepatocellular adenomas histopathologically.

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Title: Multiple hepatocellular adenomas in a patient with glycogen storage disease type I: various enhancement patterns in MRI with Gd-EOB-DTPA
Authors: Ayami Sakamoto
Hideyuki Hayashi
Ichiro Sakamoto
Ichiro Isomoto
Susumu Eguchi
Mitsuhisa Takatsuki
Tatsuki Ichikawa
Kuniko Abe
Tomayoshi Hayashi
Masataka Uetani
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: Abdominal Radiology / Issue 2/2012
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI: https://doi.org/10.1007/s00261-011-9721-1

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