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Current Psychiatry Reports
Published in: Current Psychiatry Reports 11/2014

01-11-2014 | Autism Spectrum Disorders (ES Brodkin, Section Editor)

Multimodal Imaging in Autism: an Early Review of Comprehensive Neural Circuit Characterization

Authors: Benjamin E. Yerys, John D. Herrington

Published in: Current Psychiatry Reports | Issue 11/2014

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Abstract

There is accumulating evidence that the neurobiology of autism spectrum disorders (ASD) is linked to atypical neural communication and connectivity. This body of work emphasizes the need to characterize the function of multiple regions that comprise neural circuits rather than focusing on singular regions as contributing to deficits in ASD. Multimodal neuroimaging — the formal combination of multiple functional and structural measures of the brain — is extremely promising as an approach to understanding neural deficits in ASD. This review provides an overview of the multimodal imaging approach, and then provides a snapshot of how multimodal imaging has been applied in the study of ASD to date. This body of work is separated into two categories: one concerning whole brain connectomics and the other focused on characterizing neural circuits implicated as altered in ASD. We end this review by highlighting emerging themes from the existing body of literature, and new resources that will likely influence future multimodal imaging studies.
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Metadata
Title
Multimodal Imaging in Autism: an Early Review of Comprehensive Neural Circuit Characterization
Authors
Benjamin E. Yerys
John D. Herrington
Publication date
01-11-2014
Publisher
Springer US
Published in
Current Psychiatry Reports / Issue 11/2014
Print ISSN: 1523-3812
Electronic ISSN: 1535-1645
DOI
https://doi.org/10.1007/s11920-014-0496-2

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