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European Radiology

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01-10-2013 | Interventional

MRI-guided percutaneous coaxial cutting needle biopsy of small pulmonary nodules: feasibility

Authors: Ming Liu, Yubo Lv, Lebin Wu, Jiqing Song, Roberto Blanco Sequeiros, Chengli Li

Published in: European Radiology | Issue 10/2013

Abstract

Objectives

To prospectively evaluate the feasibility, safety and accuracy of magnetic resonance imaging (MRI)-guided percutaneous coaxial cutting needle biopsy of small (≤2.0 cm in diameter) pulmonary nodules.

Methods

Ninety-six patients (56 men and 40 women) with 96 small lung nodules underwent MRI-guided percutaneous coaxial cutting needle biopsy. These lesions were divided into two groups according to maximum nodule diameters: 0.5–1.0 cm (n = 25) and 1.1–2.0 cm (n = 71). The diagnostic accuracy, sensitivity and specificity were calculated, and comparison of the two groups was performed using Fisher's exact test.

Results

All specimens obtained were sufficient for diagnosis. Histological examination of needle biopsy revealed 64 malignant, 30 benign and 2 indeterminate nodules. The final diagnoses from surgery or clinical follow-up were 67 malignant nodules and 29 benign nodules. The diagnostic performance of MRI-guided percutaneous coaxial cutting needle biopsy in diagnosing malignant tumours was as follows: accuracy, 97 %; sensitivity, 96 %; specificity, 100 %; positive predictive value, 100 %; and negative predictive value, 91 %. There was no significant difference between the two groups (P > 0.05, Fisher's exact test). No serious complications occurred.

Conclusions

MRI-guided percutaneous coaxial cutting needle biopsy is a safe and accurate diagnostic technique in the evaluation of small lung nodules.

Key Points

• MRI-guided biopsy helps clinicians to assess patients with small lung nodules.

• Differentiation of malignant and benign nodules is possible with 97 % accuracy.

• MRI guidance enables accurate lung biopsy without ionising radiation.

• No serious complications occurred in MRI-guided lung biopsy.

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Title: MRI-guided percutaneous coaxial cutting needle biopsy of small pulmonary nodules: feasibility
Authors: Ming Liu
Yubo Lv
Lebin Wu
Jiqing Song
Roberto Blanco Sequeiros
Chengli Li
Publication date: 01-10-2013
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 10/2013
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-013-2871-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

MRI-guided percutaneous coaxial cutting needle biopsy of small pulmonary nodules: feasibility

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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