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Abdominal Radiology
Published in: Abdominal Radiology 5/2015

01-06-2015

MR enterography in Crohn’s disease: current consensus on optimal imaging technique and future advances from the SAR Crohn’s disease-focused panel

Authors: David J. Grand, Flavius F. Guglielmo, Mahmoud M. Al-Hawary

Published in: Abdominal Radiology | Issue 5/2015

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Abstract

MR enterography is a powerful tool for the non-invasive evaluation of patients with Crohn’s disease (CD) without ionizing radiation. The following paper describes the current consensus on optimal imaging technique, interpretation, and future advances from the Society of Abdominal Radiology CD-focused panel.
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Literature
1.
Jaffe TA, Gaca AM, Delaney S, et al. (2007) Radiation doses from small-bowel follow-through and abdominopelvic MDCT in Crohn’s disease. Am J Roengenol 189:1015–1102CrossRef
2.
Kroeker KI, Lam S, Birchall I, et al. (2011) Patients with IBD are exposed to high levels of ionizing radiation through CT scan diagnostic imaging: a five year study. J Clin Gastroenterol 45:34–39CrossRefPubMed
3.
Fucic A, Brunborg G, Lasan R, et al. (2008) Genomic damage in children accidentally exposed to ionizing radiation: a review of the literature. Mutat Res 658:111–123CrossRefPubMed
4.
Huang JS, Tobin A, Harvey L, et al. (2001) Diagnostic medical radiation in pediatric patients with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 53(5):502–506CrossRef
5.
Sauer CG, Kugathasan S, Martin DR, et al. (2011) Medical radiation exposure in children with inflammatory bowel disease estimates high cumulative doses. Inflamm Bowel Dis 17(11):2326–2332CrossRefPubMed
6.
Guimaraes LS, Fidler JL, Fletcher JG, et al. (2010) Assessment of appropriateness of indications for CT enterography in younger patients. Inflamm Bowel Dis 16(2):226–232CrossRefPubMed
7.
Fiorino G, Bonifacio C, Peyrin-Biroulet L, et al. (2011) Prospective comparison of computed tomography enterography and magnetic resonance enterography for assessment of disease activity and complications in ileocolonic Crohn’s disase. Inflamm Bowel Dis 17(5):1073–1080CrossRefPubMed
8.
Ordás I, Rimola J, Rodríguez S, et al. (2014) Accuracy of magnetic resonance enterography in assessing response to therapy and mucosal healing in patients with Crohn’s disease. Gastroenterology 146(2):374–382CrossRefPubMed
9.
Quencer KB, Nimkin K, Mino-Kenudson M, et al. (2013) Detecting active inflammation and fibrosis in pediatric Crohn’s disease: prospective evaluation of MR-E and CT-E. Abdom Imaging 38(4):705–713CrossRefPubMedCentralPubMed
10.
Oto A, Kayhan A, Williams JT, et al. (2011) Active Crohn’s disease in the small bowel: evaluation by diffusion weighted imaging and quantitative dynamic contrast enhanced MR imaging. J Magn Reson Imaging 33:615–624CrossRefPubMed
11.
Bickelhaupt S, Froehlich JM, Cattin R, et al. (2013) Differntiation between active and chronic Crohn’s disease using MRI small-bowel motility examinations—initial experience. Clin Radiol 68(12):1247–1253CrossRefPubMed
12.
Adler J, Swanson S, Schmiedlin-Ren P, et al. (2011) Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease. Radiology 259:127–135CrossRefPubMedCentralPubMed
13.
Szurowska E, Wypch J, Izycka-Swieszewska E (2007) Perianal fistulas in Crohn’s disease: MRI diagnosis and surgical planning. Abdom Imaging 32(6):705–718CrossRefPubMed
14.
Baker ME, Einstein DM, Veniero JC (2008) Computed tomography enterography and magnetic resonance enterography: the future of small bowel imaging. Clin Colon Rectal Surg 21(3):193–212CrossRefPubMedCentralPubMed
15.
Cronin CG, Lohan DG, Mhuircheartaigh JN (2008) MRI small-bowel follow-through: prone versus supine patient positioning for best small-bowel distension and lesion detection. Am J Roengenol 191:502–506CrossRef
16.
Ajaj W, Goyen M, Schneeman H, et al. (2005) Oral contrast agents for small bowel distension in MRI: influence of the osmolarity for small bowel distension. Eur Radiol 15:1400–1406CrossRefPubMed
17.
Borthne AS, Abdelnoor M, Hellund JC, et al. (2005) MR imaging of the small bowel with increasing concentrations of an oral osmotic agent. Eur Radiol 15:667–671CrossRef
18.
Negaard A, Sandivik L, Berstad AE, et al. (2007) A prospective randomized comparison between two MRI studies of the small bowel in Crohn’s disease, the oral contrast method and MRE enteroclysis. Eur Radiol 17:2294–2301CrossRefPubMed
19.
Negaard A, Sandvik L, Berstad AE, et al. (2008) MRI of the small bowel with oral contrast or nasojejunal intubation in Crohn’s disease: randomized comparison of patient acceptance. Scand J Gastroenterol 43:44–51CrossRefPubMed
20.
Ajaj W, Lauenstein TC, Langhorst J, et al. (2005) Small bowel hydro-MR imaging for optimized ileocecal distension in Crohn’s disease: should an additional rectal enema filling be performed? J Magn Reson Imaging 22(1):92–100CrossRefPubMed
21.
Grand DJ, Beland MD, Machan JT, et al. (2012) Detection of Crohn’s disease: comparison of CT and MR enterography without anti-peristaltic agents performed on the same day. Eur J Radiol 81(8):1735–1741CrossRefPubMed
22.
Grand DJ, Kampalath V, Harris A, et al. (2012) MR enterography correlates highly with colonoscopy and histology for both distal ileal and colonic Crohn’s disease in 310 patients. Eur J Radiol 81(5):e763–e769CrossRefPubMed
23.
Al-Hawary M, Zimmermann EM (2012) A new look at Crohn’s disease: novel imaging techniques. Curr Opin Gastroenterol 28(4):334–340PubMed
24.
25.
Oto A, Kayhan A, Williams JT, et al. (2011) Active Crohn’s disease in the small bowel: evaluation by diffusion weighted imaging and quantitative dynamic contrast enhanced MR imaging. J Magn Reson Imaging 33(3):615–624CrossRefPubMed
26.
Ream JM, Dillman JR, Adler J, et al. (2013) MRI diffusion-weighted imaging (DWI) in pediatric small bowel Crohn disease: correlation with MRI findings of active bowel wall inflammation. Pediatr Radiol 43(9):1077–1085CrossRefPubMed
27.
Hordonneau C, Buisson A, Scanzi J, et al. (2014) Diffusion-weighted magnetic resonance imaging in ileocolonic Crohn’s disease: validation of quantitative index of activity. Am J Gastroenterol 109(1):89–98CrossRefPubMed
28.
Adler J, Swanson SD, Schmiedlin-Ren P, et al. (2011) Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease. Radiology 259(1):127–135CrossRefPubMedCentralPubMed
29.
Wakamiya M, Furukawa A, Kanasaki S, et al. (2011) Assessment of small bowel motility function with cine-MRI using balanced steady-state free precession sequence. J Magn Reson Imaging 33:1235–1240CrossRefPubMed
30.
Froehlich JM, Patek MA, von Weymarn C, et al. (2005) Small bowel motility assessment with magnetic resonance imaging. J Magn Reson Imaging 21:370–375CrossRefPubMed
31.
Odille F, Menys A, Ahmed A, et al. (2012) Quantitative assessment of small bowel motility by nonrigid registration of dynamic MR images. Magn Reson Med 68(3):783–793CrossRefPubMed
32.
Heye T, Stein D, Antolovic D, et al. (2012) Evaluation of bowel peristalsis by dynamic cine MRI: detection of relevant functional disturbances—initial experience. J Magn Reson Imaging 35:859–867CrossRefPubMed
33.
Siddiki H, Fidler J (2009) MR imaging of the small bowel in Crohn’s disease. Eur J Radiol 69:409–417CrossRefPubMed
34.
Fletcher JG, Fidler JL, Bruining DH, et al. (2011) New concepts in intestinal imaging for inflammatory bowel diseases. Gastroenterology 140:1795–1806CrossRefPubMed
35.
Lee S, Ha H, Yang S, et al. (2002) CT of prominent pericolic or perienteric vasculature in patients with Crohn’s disease: correlation with clinical disease activity and findings on barium studies. Am J Roengenol 179:1029–1036CrossRef
36.
Koh DM, Miao Y, Chinn RJS (2001) MR imaging evaluation of the activity of Crohn’s disease. Am J Roengenol 177:1325–1332CrossRef
37.
Sempere GAJ, Sanjuan VM, Chulia EM, et al. (2005) MRI evaluation of inflammatory activity in Crohn’s disease. Am J Roengenol 184:1829–1835CrossRef
38.
Rimola J, Rodriguez S, Garcia-Bosch O, et al. (2009) Magnetic resonance for assessment of disease activity and severity in ileocolonic Crohn’s disease. Gut 58:1113–1120CrossRefPubMed
39.
Maccioni F, Bruni A, Viscido A, et al. (2006) MR imaging in patients with Crohn Disease: value of T2- versus T1-weighted gadolinium-enhanced MR sequences with use of an oral superparamagnetic contrast agent. Radiology 238(2):517–530CrossRefPubMed
40.
Adler J, Punglia DR, Dillman JR, et al. (2012) Computed tomography enterography findings correlate with tissue inflammation, not fibrosis in resected small bowel Crohn’s disease. Inflamm Bowel Dis 18(5):849–856CrossRefPubMed
41.
Rieder F, Fiocchi C (2009) Intestinal fibrosis in IBD—a dynamic, multifactorial process. Nat Rev Gastroenterol Hepatol 6:228–235CrossRefPubMed
42.
Messaris E, Chandolias N, Grand DJ, et al. (2010) Role of magnetic resonance enterography in the management of Crohn disease. Arch Surg 145(5):471–475CrossRefPubMed
43.
Gee MS, Nimkin K, Hsu M, et al. (2011) Prospective evaluation of MR enterography as the primary imaging modality for pediatric Crohn’s disease assessment. Am J Roengenol 197(1):224–231CrossRef
44.
Pozza A, Scarpa M, Lacognata C, et al. (2011) Magnetic resonance enterography for Crohn’s disease: what the surgeon can take home. J Gastrointest Surg 15:1689–1698CrossRefPubMed
45.
Smith EA, Dillman JR, Adler J (2012) MR enterography of extraluminal manifestations of inflammatory bowel disease in children and adolescents: moving beyond the bowel wall. Am J Roengenol 198:W38–W45CrossRef
46.
Rimola J, Ordas I, Rodriguez S, et al. (2011) Magnetic resonance imaging for evaluation of Crohn’s disease: validation of parameters of severity and quantitative index of activity. Inflamm Bowel Dis 17:1759–1768CrossRefPubMed
47.
Lawrance IC, Welman CJ, Shipman P, et al. (2009) Correlation of MRI-determined small bowel Crohn’s disease categories with medical response and surgical pathology. World J Gastroenterol 15(27):3367–3375CrossRefPubMedCentralPubMed
48.
Steward MJ, Punwani S, Proctor I, et al. (2012) Non-perforating small bowel Crohn’s disease assessed by MRI enterography: derivation and histopathological validation of an MR-based activity index. Eur J Radiol 81:2080–2088CrossRefPubMed
Metadata
Title
MR enterography in Crohn’s disease: current consensus on optimal imaging technique and future advances from the SAR Crohn’s disease-focused panel
Authors
David J. Grand
Flavius F. Guglielmo
Mahmoud M. Al-Hawary
Publication date
01-06-2015
Publisher
Springer US
Published in
Abdominal Radiology / Issue 5/2015
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-015-0361-8

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