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Social Psychiatry and Psychiatric Epidemiology
Published in: Social Psychiatry and Psychiatric Epidemiology 12/2015

Open Access 01-12-2015 | Review

Mother–infant interaction in schizophrenia: transmitting risk or resilience? A systematic review of the literature

Authors: Kirstine Agnete Davidsen, Susanne Harder, Angus MacBeth, Jenna-Marie Lundy, Andrew Gumley

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 12/2015

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Abstract

Purpose

The parent–infant relationship is an important context for identifying very early risk and resilience factors and targets for the development of preventative interventions. The aim of this study was to systematically review studies investigating the early caregiver–infant relationship and attachment in offspring of parents with schizophrenia.

Methods

We searched computerized databases for relevant articles investigating the relationship between early caregiver–infant relationship and outcomes for offspring of a caregiver with a diagnosis of schizophrenia. Studies were assessed for risk of bias.

Results

We identified 27 studies derived from 10 cohorts, comprising 208 women diagnosed with schizophrenia, 71 with other psychoses, 203 women with depression, 59 women with mania/bipolar disorder, 40 with personality disorder, 8 with unspecified mental disorders and 119 non-psychiatric controls. There was some evidence to support disturbances in maternal behaviour amongst those with a diagnosis of schizophrenia and there was more limited evidence of disturbances in infant behaviour and mutuality of interaction.

Conclusions

Further research should investigate both sources of resilience and risk in the development of offspring of parents with a diagnosis of schizophrenia and psychosis. Given the lack of specificity observed in this review, these studies should also include maternal affective disorders including depressive and bipolar disorders.
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Metadata
Title
Mother–infant interaction in schizophrenia: transmitting risk or resilience? A systematic review of the literature
Authors
Kirstine Agnete Davidsen
Susanne Harder
Angus MacBeth
Jenna-Marie Lundy
Andrew Gumley
Publication date
01-12-2015
Publisher
Springer Berlin Heidelberg
Published in
Social Psychiatry and Psychiatric Epidemiology / Issue 12/2015
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-015-1127-x

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