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Open Access 01-12-2022 | Mood Disorders | Research

Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study

Authors: Achille Tchalla, Cécile Laubarie-Mouret, Noëlle Cardinaud, Caroline Gayot, Marion Rebiere, Nathalie Dumoitier, Karen Rudelle, Michel Druet-Cabanac, Marie-Laure Laroche, Sophie Boyer

Published in: BMC Geriatrics | Issue 1/2022

Abstract

Background

Frailty is a geriatric syndrome associated with disability and negative health outcome. To determine the factors associated with frailty and functional disability in older participants living in community in France. We included 753 community-dwelling old participants with available frailty data at baseline.

Results

Overall, 31.9% were frail, 58.3% were prefrail, and 9.8% were robust. The SMAF (French acronym for Functional Autonomy Measurement System) score was significantly lower (mean ± standard deviation: -25.8 ± 11.2) in frail participants compared to prefrail (-14.3 ± 9.7) or robust participants (-8.1 ± 7.0); 82% of frail older participants had limitation in at least one ADL and 97.5% in at least one IADL compared to 54.2 and 76.8%, respectively of pre-frail and 29.7 and 47.3% of robust participants. Age, depression, impaired cognition and diabetes were significantly associated with higher odds of frailty. These variables were also strongly associated with functional disability. Female gender, polypharmacy, and smoking were additional variables significantly associated with degraded SMAF and/or ADL/IADL.

Conclusions

This study showed that functional disability increased proportionally to frailty, and depression, cognitive decline and diabetes are modifiable risk factors significantly associated with frailty and functional disability.

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Title: Risk factors of frailty and functional disability in community-dwelling older adults: a cross-sectional analysis of the FREEDOM-LNA cohort study
Authors: Achille Tchalla
Cécile Laubarie-Mouret
Noëlle Cardinaud
Caroline Gayot
Marion Rebiere
Nathalie Dumoitier
Karen Rudelle
Michel Druet-Cabanac
Marie-Laure Laroche
Sophie Boyer
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Mood Disorders
Affective Disorder
Published in: BMC Geriatrics / Issue 1/2022
Electronic ISSN: 1471-2318
DOI: https://doi.org/10.1186/s12877-022-03447-z

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