Skip to main content
Top
Published in: BMC Nephrology 1/2013

Open Access 01-12-2013 | Research article

Monitoring of hemodialysis quality-of-care indicators: why is it important?

Authors: Steven Grangé, Mélanie Hanoy, Frank Le Roy, Dominique Guerrot, Michel Godin

Published in: BMC Nephrology | Issue 1/2013

Login to get access

Abstract

Background

Meeting specific guideline targets is associated with improved survival rates and reduced hospitalizations in the dialysis population. This prospective work evaluated the adequacy of hemodialysis quality indicators in an in-center hemodialysis population with severe comorbidities, and assessed whether clinical practice could impact intermediate outcomes.

Methods

All the chronic hemodialysis patients treated in Rouen University Hospital hemodialysis Unit between January 2009 and April 2010 were included in this observational study. Every quarter, mean levels and prevalence of conformity were collected for the following indicators: anemia, dialysis dose, serum calcium and phosphorus, PTH, 25OH-vitamin D, albumin, serum bicarbonate, LDL-cholesterol, serum β2-microglobulin, systolic and diastolic blood pressure, intradialytic hypotension and vascular access. Conformity of quality-of-care indicators was determined according to targets defined by international guidelines, whenever available.

Results

Altogether, 124 patients were included in the study. Thirty-three patients were evaluated during the entire follow-up period. An improvement in the percentage of conformity was observed for hemoglobin, dialysis dose, phosphates, PTH, serum bicarbonate and β2-microglobulin in the global population. Failure to improve conformity rates for several indicators, including serum albumin, was found, possibly depending on patients’ comorbidities rather than on quality of care.

Conclusion

Overall, this study shows that following quality-of-care indicators can improve clinical practice by identifying center-specific weaknesses, prompting the establishment of corrective measures. Finally, we suggest that the definition and targets of some indicators, especially hypertension and LDL-cholesterol, be reviewed, since evidence of their association with mortality is not demonstrated.
Appendix
Available only for authorised users
Literature
1.
go back to reference Kramer A, Stel V, Zoccali C, Heaf G, Ansell D, Grönhagen-Riska C, Leivestad T, Simpson K, Palsson R, Postorino M, Jager K: An update on renal replacement therapy in Europe: ERA-EDTA Registry data from 1997 to 2006. Nephrol Dial Transplant. 2009, 24: 3557-3566. 10.1093/ndt/gfp519.CrossRefPubMed Kramer A, Stel V, Zoccali C, Heaf G, Ansell D, Grönhagen-Riska C, Leivestad T, Simpson K, Palsson R, Postorino M, Jager K: An update on renal replacement therapy in Europe: ERA-EDTA Registry data from 1997 to 2006. Nephrol Dial Transplant. 2009, 24: 3557-3566. 10.1093/ndt/gfp519.CrossRefPubMed
2.
go back to reference Rocco MV, Frankenfield DL, Hopson SD, McClellan WM: Relationship between clinical performance measures and outcomes among patients receiving long-term hemodialysis. Ann Intern Med. 2006, 145: 512-519. 10.7326/0003-4819-145-7-200610030-00009.CrossRefPubMed Rocco MV, Frankenfield DL, Hopson SD, McClellan WM: Relationship between clinical performance measures and outcomes among patients receiving long-term hemodialysis. Ann Intern Med. 2006, 145: 512-519. 10.7326/0003-4819-145-7-200610030-00009.CrossRefPubMed
3.
go back to reference Plantinga LC, Fink NE, Jaar BG, Sadler JH, Levin NW, Coresh J, Klag MJ, Powe NR: Attainment of clinical performance targets and improvement in clinical outcomes and resource use in hemodialysis care: a prospective cohort study. BMC Health Serv Res. 2007, 7: 5-10.1186/1472-6963-7-5.CrossRefPubMedPubMedCentral Plantinga LC, Fink NE, Jaar BG, Sadler JH, Levin NW, Coresh J, Klag MJ, Powe NR: Attainment of clinical performance targets and improvement in clinical outcomes and resource use in hemodialysis care: a prospective cohort study. BMC Health Serv Res. 2007, 7: 5-10.1186/1472-6963-7-5.CrossRefPubMedPubMedCentral
4.
go back to reference Canaud B, Combe C, Bragg-Gresham JL, Eichleay MA, Pisoni RL, Port FK: DOPPS estimate of patient life years attributable to modifiable hemodialysis practices in France. Nephrol Ther. 2008, 4: 256-265. 10.1016/j.nephro.2008.01.003.CrossRefPubMed Canaud B, Combe C, Bragg-Gresham JL, Eichleay MA, Pisoni RL, Port FK: DOPPS estimate of patient life years attributable to modifiable hemodialysis practices in France. Nephrol Ther. 2008, 4: 256-265. 10.1016/j.nephro.2008.01.003.CrossRefPubMed
5.
go back to reference Tentori F, Hunt WC, Rohrscheib M, Zhu M, Stidley CA, Servilla K, Miskulin D, Meyer KB, Bedrick EJ, Johnson HK, Zager PG: Which targets in clinical practice guidelines are associated with improved survival in a large dialysis organization?. J Am Soc Nephrol. 2007, 18: 2377-2384. 10.1681/ASN.2006111250.CrossRefPubMed Tentori F, Hunt WC, Rohrscheib M, Zhu M, Stidley CA, Servilla K, Miskulin D, Meyer KB, Bedrick EJ, Johnson HK, Zager PG: Which targets in clinical practice guidelines are associated with improved survival in a large dialysis organization?. J Am Soc Nephrol. 2007, 18: 2377-2384. 10.1681/ASN.2006111250.CrossRefPubMed
6.
go back to reference Fink JC, Zhan M, Blahut SA, Soucie M, McClellan WM: Measuring the efficacy of a quality improvement program in dialysis adequacy with changes in center effects. J Am Soc Nephrol. 2002, 13: 2338-2344. 10.1097/01.ASN.0000027978.98194.1F.CrossRefPubMed Fink JC, Zhan M, Blahut SA, Soucie M, McClellan WM: Measuring the efficacy of a quality improvement program in dialysis adequacy with changes in center effects. J Am Soc Nephrol. 2002, 13: 2338-2344. 10.1097/01.ASN.0000027978.98194.1F.CrossRefPubMed
7.
go back to reference K/DOQI workgroup: K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis. 2005, 45: S1-S153. K/DOQI workgroup: K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis. 2005, 45: S1-S153.
8.
go back to reference Koubaa A, Potier J, De Préneuf H, Queffelou G, Garcia F, Petitclerc T: Estimation of urea distribution volume in hemodialysis patients. Nephrol Ther. 2010, 6: 532-536. 10.1016/j.nephro.2010.04.007.CrossRefPubMed Koubaa A, Potier J, De Préneuf H, Queffelou G, Garcia F, Petitclerc T: Estimation of urea distribution volume in hemodialysis patients. Nephrol Ther. 2010, 6: 532-536. 10.1016/j.nephro.2010.04.007.CrossRefPubMed
9.
go back to reference Maggiore Q, Pizzarelli F, Santoro A, Panzetta G, Bonforte G, Hannedouche T, de Lara MA A, Tsouras I, Loureiro A, Ponce P, Sulkovà S, Van Roost G, Brink H, Kwan JT: The effects of control of thermal balance on vascular stability in hemodialysis patients: results of the European randomized clinical trial. Am J Kidney Dis. 2002, 40: 280-290. 10.1053/ajkd.2002.34506.CrossRefPubMed Maggiore Q, Pizzarelli F, Santoro A, Panzetta G, Bonforte G, Hannedouche T, de Lara MA A, Tsouras I, Loureiro A, Ponce P, Sulkovà S, Van Roost G, Brink H, Kwan JT: The effects of control of thermal balance on vascular stability in hemodialysis patients: results of the European randomized clinical trial. Am J Kidney Dis. 2002, 40: 280-290. 10.1053/ajkd.2002.34506.CrossRefPubMed
10.
go back to reference de Paula FM, Peixoto AJ, Pinto LV, Dorigo D, Patricio PJ, Santos SF: Clinical consequences of an individualized dialysate sodium prescription in hemodialysis patients. Kidney Int. 2004, 66: 1232-1238. 10.1111/j.1523-1755.2004.00876.x.CrossRefPubMed de Paula FM, Peixoto AJ, Pinto LV, Dorigo D, Patricio PJ, Santos SF: Clinical consequences of an individualized dialysate sodium prescription in hemodialysis patients. Kidney Int. 2004, 66: 1232-1238. 10.1111/j.1523-1755.2004.00876.x.CrossRefPubMed
11.
go back to reference K/DOQI workgroup: KDOQI Clinical Practice Guideline and Clinical Practice Recommendations for anemia in chronic kidney disease: 2007 update of hemoglobin target. Am J Kidney Dis. 2007, 50: 471-530.CrossRef K/DOQI workgroup: KDOQI Clinical Practice Guideline and Clinical Practice Recommendations for anemia in chronic kidney disease: 2007 update of hemoglobin target. Am J Kidney Dis. 2007, 50: 471-530.CrossRef
12.
go back to reference Moe SM, Drüeke TB, Block GA, Cannata-Andia JB, Elder GJ, Fukagawa M, Jorgetti V, Ketteler M, Langman CB, Levin A, MacLeod AM, McCann L, McCullough PA, Ott SM, Wang AY, Weisinger JR, Wheeler DC, Persson R, Earley A, Moorthi R, Uhlig K: KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Kidney Int Suppl. 2009, : S1-S130. Moe SM, Drüeke TB, Block GA, Cannata-Andia JB, Elder GJ, Fukagawa M, Jorgetti V, Ketteler M, Langman CB, Levin A, MacLeod AM, McCann L, McCullough PA, Ott SM, Wang AY, Weisinger JR, Wheeler DC, Persson R, Earley A, Moorthi R, Uhlig K: KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Kidney Int Suppl. 2009, : S1-S130.
13.
go back to reference Fouque D, Vennegoor M, ter Wee P, Wanner C, Basci A, Canaud B, Haage P, Konner K, Kooman J, Martin-Malo A, Pedrini L, Pizzarelli F, Tattersall J, Tordoir J, Vanholder R: EBPG guideline on nutrition. Nephrol Dial Transplant. 2007, 22 (Suppl 2): ii45-ii87.PubMed Fouque D, Vennegoor M, ter Wee P, Wanner C, Basci A, Canaud B, Haage P, Konner K, Kooman J, Martin-Malo A, Pedrini L, Pizzarelli F, Tattersall J, Tordoir J, Vanholder R: EBPG guideline on nutrition. Nephrol Dial Transplant. 2007, 22 (Suppl 2): ii45-ii87.PubMed
14.
go back to reference Lowrie EG, Li Z, Ofsthun NJ: Evaluating a new method to judge dialysis treatment using online measurements of ionic clearance. Kidney Int. 2006, 70: 211-217. 10.1038/sj.ki.5001507.CrossRefPubMed Lowrie EG, Li Z, Ofsthun NJ: Evaluating a new method to judge dialysis treatment using online measurements of ionic clearance. Kidney Int. 2006, 70: 211-217. 10.1038/sj.ki.5001507.CrossRefPubMed
15.
go back to reference Lowrie EG: Prescribing and monitoring hemodialysis dose. Kidney Int. 2008, 74: 262-264. 10.1038/ki.2008.224.CrossRefPubMed Lowrie EG: Prescribing and monitoring hemodialysis dose. Kidney Int. 2008, 74: 262-264. 10.1038/ki.2008.224.CrossRefPubMed
16.
go back to reference Zager PG, Nikolic J, Brown RH, Campbell MA, Hunt WC, Peterson D, Van Stone J, Levey A, Meyer KB, Klag MJ, Johnson HK, Clark E, Sadler JH, Teredesai P: “U” curve association of blood pressure and mortality in hemodialysis patients. Medical Directors of Dialysis Clinic, Inc. Kidney Int. 1998, 54: 561-569. 10.1046/j.1523-1755.1998.00005.x.CrossRefPubMed Zager PG, Nikolic J, Brown RH, Campbell MA, Hunt WC, Peterson D, Van Stone J, Levey A, Meyer KB, Klag MJ, Johnson HK, Clark E, Sadler JH, Teredesai P: “U” curve association of blood pressure and mortality in hemodialysis patients. Medical Directors of Dialysis Clinic, Inc. Kidney Int. 1998, 54: 561-569. 10.1046/j.1523-1755.1998.00005.x.CrossRefPubMed
17.
go back to reference Lacson E, Wang W, Hakim RM, Teng M, Lazarus JM: Associates of mortality and hospitalization in hemodialysis: potentially actionable laboratory variables and vascular access. Am J Kidney Dis. 2009, 53: 79-90. 10.1053/j.ajkd.2008.07.031.CrossRefPubMed Lacson E, Wang W, Hakim RM, Teng M, Lazarus JM: Associates of mortality and hospitalization in hemodialysis: potentially actionable laboratory variables and vascular access. Am J Kidney Dis. 2009, 53: 79-90. 10.1053/j.ajkd.2008.07.031.CrossRefPubMed
18.
go back to reference Phrommintikul A, Haas SJ, Elsik M, Krum H: Mortality and target hemoglobin concentrations in anaemic patients with chronic kidney disease treated with erythropoietin: a meta-analysis. Lancet. 2007, 369: 381-388. 10.1016/S0140-6736(07)60194-9.CrossRefPubMed Phrommintikul A, Haas SJ, Elsik M, Krum H: Mortality and target hemoglobin concentrations in anaemic patients with chronic kidney disease treated with erythropoietin: a meta-analysis. Lancet. 2007, 369: 381-388. 10.1016/S0140-6736(07)60194-9.CrossRefPubMed
19.
go back to reference Eknoyan G, Beck GJ, Cheung AK, Daugirdas JT, Greene T, Kusek JW, Allon M, Bailey J, Delmez JA, Depner TA, Levey AS, Levin NW, Milford E, Ornt DB, Rocco MV, Schulman G, Schwab SJ, Teehan BP, Toto R, Dwyer: Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med. 2002, 347: 2010-2009. 10.1056/NEJMoa021583.CrossRefPubMed Eknoyan G, Beck GJ, Cheung AK, Daugirdas JT, Greene T, Kusek JW, Allon M, Bailey J, Delmez JA, Depner TA, Levey AS, Levin NW, Milford E, Ornt DB, Rocco MV, Schulman G, Schwab SJ, Teehan BP, Toto R, Dwyer: Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med. 2002, 347: 2010-2009. 10.1056/NEJMoa021583.CrossRefPubMed
20.
go back to reference Canaud B, Bragg-Gresham JL, Marshall MR, Desmeules S, Gillespie BW, Depner T, Klassen P, Port FK: Mortality risk for patients receiving hemodiafiltration versus hemodialysis: European results from the DOPPS. Kidney Int. 2006, 69: 2087-2093. 10.1038/sj.ki.5000447.CrossRefPubMed Canaud B, Bragg-Gresham JL, Marshall MR, Desmeules S, Gillespie BW, Depner T, Klassen P, Port FK: Mortality risk for patients receiving hemodiafiltration versus hemodialysis: European results from the DOPPS. Kidney Int. 2006, 69: 2087-2093. 10.1038/sj.ki.5000447.CrossRefPubMed
21.
go back to reference Lowrie EG, Li Z, Ofsthun N: The online measurement of hemodialysis dose (Kt): clinical outcome as a function of body surface area. Kidney Int. 2005, 68: 1344-1354. 10.1111/j.1523-1755.2005.00533.x.CrossRefPubMed Lowrie EG, Li Z, Ofsthun N: The online measurement of hemodialysis dose (Kt): clinical outcome as a function of body surface area. Kidney Int. 2005, 68: 1344-1354. 10.1111/j.1523-1755.2005.00533.x.CrossRefPubMed
22.
go back to reference Amar J, Vernier I, Rossignol E, Bongard V, Arnaud C, Conte JJ, Salvador M, Chamontin B: Nocturnal blood pressure and 24-hour pulse pressure are potent indicators of mortality in hemodialysis patients. Kidney Int. 2000, 57: 2485-2491. 10.1046/j.1523-1755.2000.00107.x.CrossRefPubMed Amar J, Vernier I, Rossignol E, Bongard V, Arnaud C, Conte JJ, Salvador M, Chamontin B: Nocturnal blood pressure and 24-hour pulse pressure are potent indicators of mortality in hemodialysis patients. Kidney Int. 2000, 57: 2485-2491. 10.1046/j.1523-1755.2000.00107.x.CrossRefPubMed
23.
go back to reference Alborzi P, Patel N, Agarwal R: Home blood pressures are of greater prognostic value than hemodialysis unit recordings. Clin J Am Soc Nephrol. 2007, 2: 1228-1234. 10.2215/CJN.02250507.CrossRefPubMed Alborzi P, Patel N, Agarwal R: Home blood pressures are of greater prognostic value than hemodialysis unit recordings. Clin J Am Soc Nephrol. 2007, 2: 1228-1234. 10.2215/CJN.02250507.CrossRefPubMed
24.
go back to reference Owen WF, Lew NL, Liu Y, Lowrie EG, Lazarus JM: The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med. 1993, 329: 1001-1006. 10.1056/NEJM199309303291404.CrossRefPubMed Owen WF, Lew NL, Liu Y, Lowrie EG, Lazarus JM: The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med. 1993, 329: 1001-1006. 10.1056/NEJM199309303291404.CrossRefPubMed
25.
go back to reference Saudan P, Kossovsky M, Halabi G, Martin PY, Pernerger TV: Quality of care and survival of hemodialysed patients in western Switzerland. Nephrol Dial Transplant. 2008, 23: 1975-1981. 10.1093/ndt/gfm915.CrossRefPubMed Saudan P, Kossovsky M, Halabi G, Martin PY, Pernerger TV: Quality of care and survival of hemodialysed patients in western Switzerland. Nephrol Dial Transplant. 2008, 23: 1975-1981. 10.1093/ndt/gfm915.CrossRefPubMed
26.
go back to reference Kaysen GA, Dubin JA, Muller HG, Mitch WE, Rosales LM, Levin NW: Relationships among inflammation nutrition and physiologic mechanisms establishing albumin levels in hemodialysis patients. Kidney Int. 2002, 61: 2240-2249. 10.1046/j.1523-1755.2002.00076.x.CrossRefPubMed Kaysen GA, Dubin JA, Muller HG, Mitch WE, Rosales LM, Levin NW: Relationships among inflammation nutrition and physiologic mechanisms establishing albumin levels in hemodialysis patients. Kidney Int. 2002, 61: 2240-2249. 10.1046/j.1523-1755.2002.00076.x.CrossRefPubMed
27.
go back to reference Leon JB, Albert JM, Gilchrist G, Kushner I, Lerner E, Mach S, Majerle A, Porter D, Ricanati E, Sperry L, Sullivan C, Zimmerer J, Sehgal AR: Improving albumin levels among hemodialysis patients: a community-based randomized controlled trial. Am J Kidney Dis. 2006, 48: 28-36. 10.1053/j.ajkd.2006.03.046.CrossRefPubMed Leon JB, Albert JM, Gilchrist G, Kushner I, Lerner E, Mach S, Majerle A, Porter D, Ricanati E, Sperry L, Sullivan C, Zimmerer J, Sehgal AR: Improving albumin levels among hemodialysis patients: a community-based randomized controlled trial. Am J Kidney Dis. 2006, 48: 28-36. 10.1053/j.ajkd.2006.03.046.CrossRefPubMed
28.
go back to reference Clase CM, St Pierre MW, Churchill DN: Conversion between bromocresol green- and bromcresol purple-measured albumin in renal disease. Nephrol Dial Transplant. 2001, 16: 1925-1929. 10.1093/ndt/16.9.1925.CrossRefPubMed Clase CM, St Pierre MW, Churchill DN: Conversion between bromocresol green- and bromcresol purple-measured albumin in renal disease. Nephrol Dial Transplant. 2001, 16: 1925-1929. 10.1093/ndt/16.9.1925.CrossRefPubMed
29.
go back to reference Bommer J, Locatelli F, Satayathum S, Keen ML, Goodkin DA, Saito A, Akiba T, Port FK, Young EW: Association of predialysis serum bicarbonate levels with risk of mortality and hospitalization in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2004, 44: 661-671.CrossRefPubMed Bommer J, Locatelli F, Satayathum S, Keen ML, Goodkin DA, Saito A, Akiba T, Port FK, Young EW: Association of predialysis serum bicarbonate levels with risk of mortality and hospitalization in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2004, 44: 661-671.CrossRefPubMed
30.
go back to reference Gabutti L, Ferrari N, Giudici G, Mombelli G, Marone C: Unexpected hemodynamic instability associated with standard bicarbonate hemodialysis. Nephrol Dial Transplant. 2003, 18: 2369-7. 10.1093/ndt/gfg383.CrossRefPubMed Gabutti L, Ferrari N, Giudici G, Mombelli G, Marone C: Unexpected hemodynamic instability associated with standard bicarbonate hemodialysis. Nephrol Dial Transplant. 2003, 18: 2369-7. 10.1093/ndt/gfg383.CrossRefPubMed
31.
go back to reference Lowrie EG, Huang WH, Lew NL: Death risk predictors among peritoneal dialysis and hemodialysis patients: a preliminary comparison. Am J Kidney Dis. 1995, 26: 220-228. 10.1016/0272-6386(95)90177-9.CrossRefPubMed Lowrie EG, Huang WH, Lew NL: Death risk predictors among peritoneal dialysis and hemodialysis patients: a preliminary comparison. Am J Kidney Dis. 1995, 26: 220-228. 10.1016/0272-6386(95)90177-9.CrossRefPubMed
32.
go back to reference Wanner C, Krane V, März W, Olschewski M, Mann JF, Ruf G, Ritz E: Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med. 2005, 353: 238-248. 10.1056/NEJMoa043545.CrossRefPubMed Wanner C, Krane V, März W, Olschewski M, Mann JF, Ruf G, Ritz E: Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med. 2005, 353: 238-248. 10.1056/NEJMoa043545.CrossRefPubMed
33.
go back to reference Fellstrom BC, Jardine AG, Schmieder RE, Holdaas H, Bannister K, Beutler J, Chae DW, Chevaile A, Cobbe SM, Grönhagen-Riska C, De Lima JJ, Lins R, Mayer G, McMahon AW, Parving HH, Remuzzi G, Samuelsson O, Sonkodi S, Sci D, Süleymanlar G, Tsakiris D, Tesar V, Todorov V, Wiecek A, Wüthrich RP, Gottlow M, Johnsson E, Zannad F: Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med. 2009, 360: 1395-1407. 10.1056/NEJMoa0810177.CrossRefPubMed Fellstrom BC, Jardine AG, Schmieder RE, Holdaas H, Bannister K, Beutler J, Chae DW, Chevaile A, Cobbe SM, Grönhagen-Riska C, De Lima JJ, Lins R, Mayer G, McMahon AW, Parving HH, Remuzzi G, Samuelsson O, Sonkodi S, Sci D, Süleymanlar G, Tsakiris D, Tesar V, Todorov V, Wiecek A, Wüthrich RP, Gottlow M, Johnsson E, Zannad F: Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med. 2009, 360: 1395-1407. 10.1056/NEJMoa0810177.CrossRefPubMed
34.
go back to reference Pelletier S, Roth H, Bouchet JL, Drueke T, Hannedouche T, London G, Fouque D: Mineral and bone status in French maintenance hemodialysis patients: a comparison of June 2005 and June 2008. Nephrol Ther. 2010, 6 (1): 11-20. 10.1016/j.nephro.2009.09.001.CrossRefPubMed Pelletier S, Roth H, Bouchet JL, Drueke T, Hannedouche T, London G, Fouque D: Mineral and bone status in French maintenance hemodialysis patients: a comparison of June 2005 and June 2008. Nephrol Ther. 2010, 6 (1): 11-20. 10.1016/j.nephro.2009.09.001.CrossRefPubMed
35.
go back to reference Tentori F, Blayney MJ, Albert JM, Gillespie BW, Kerr PG, Bommer J, Young EW, Akizawa T, Akiba T, Pisoni RL, Robinson BM, Port FK: Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2008, 52: 519-530. 10.1053/j.ajkd.2008.03.020.CrossRefPubMed Tentori F, Blayney MJ, Albert JM, Gillespie BW, Kerr PG, Bommer J, Young EW, Akizawa T, Akiba T, Pisoni RL, Robinson BM, Port FK: Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2008, 52: 519-530. 10.1053/j.ajkd.2008.03.020.CrossRefPubMed
36.
go back to reference Block GA, Klassen PS, Lazarus JM, Ofsthun N, Lowrie EG, Chertow GM: Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol. 2004, 15: 2208-2218. 10.1097/01.ASN.0000133041.27682.A2.CrossRefPubMed Block GA, Klassen PS, Lazarus JM, Ofsthun N, Lowrie EG, Chertow GM: Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol. 2004, 15: 2208-2218. 10.1097/01.ASN.0000133041.27682.A2.CrossRefPubMed
37.
go back to reference Kalantar-Zadeh K, Kuwae N, Regidor DL, Kovesdy CP, Kilpatrick RD, Shinaberger CS, McAliister CJ, Budoff MJ, Salusky IB, Koplle JD: Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int. 2006, 70: 771-780. 10.1038/sj.ki.5001514.CrossRefPubMed Kalantar-Zadeh K, Kuwae N, Regidor DL, Kovesdy CP, Kilpatrick RD, Shinaberger CS, McAliister CJ, Budoff MJ, Salusky IB, Koplle JD: Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int. 2006, 70: 771-780. 10.1038/sj.ki.5001514.CrossRefPubMed
38.
go back to reference Foley RN, Parfrey PS, Harnett JD, Kent GM, Hu L, O’Dea R, Murray DC, Barre PE: Hypocalcemia, morbidity, and mortality in end-stage renal disease. Am J Nephrol. 1996, 16: 386-393. 10.1159/000169030.CrossRefPubMed Foley RN, Parfrey PS, Harnett JD, Kent GM, Hu L, O’Dea R, Murray DC, Barre PE: Hypocalcemia, morbidity, and mortality in end-stage renal disease. Am J Nephrol. 1996, 16: 386-393. 10.1159/000169030.CrossRefPubMed
39.
go back to reference Block GA, Hulbert-Shearon TE, Levin NW, Port FK: Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am J Kidney Dis. 1998, 31: 607-617. 10.1053/ajkd.1998.v31.pm9531176.CrossRefPubMed Block GA, Hulbert-Shearon TE, Levin NW, Port FK: Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am J Kidney Dis. 1998, 31: 607-617. 10.1053/ajkd.1998.v31.pm9531176.CrossRefPubMed
40.
go back to reference Penne EL, van der Weerd NC, van den Dorpel MA, Grooteman MP, Lévesque R, Nubé MJ, Bots ML, Blankestijn PJ, ter Wee PM: Short-term effects of online hemodiafiltration on phosphate control: a result from the randomized controlled Convective Transport Study (CONTRAST). Am J Kidney Dis. 2010, 55: 77-87. 10.1053/j.ajkd.2009.09.023.CrossRefPubMed Penne EL, van der Weerd NC, van den Dorpel MA, Grooteman MP, Lévesque R, Nubé MJ, Bots ML, Blankestijn PJ, ter Wee PM: Short-term effects of online hemodiafiltration on phosphate control: a result from the randomized controlled Convective Transport Study (CONTRAST). Am J Kidney Dis. 2010, 55: 77-87. 10.1053/j.ajkd.2009.09.023.CrossRefPubMed
41.
go back to reference Davenport A, Gardner C, Delaney M: The effect of dialysis modality on phosphate control : hemodialysis compared to hemodiafiltration. The Pan Thames Renal Audit. Nephrol Dial Transplant. 2010, 25: 897-901. 10.1093/ndt/gfp560.CrossRefPubMed Davenport A, Gardner C, Delaney M: The effect of dialysis modality on phosphate control : hemodialysis compared to hemodiafiltration. The Pan Thames Renal Audit. Nephrol Dial Transplant. 2010, 25: 897-901. 10.1093/ndt/gfp560.CrossRefPubMed
42.
go back to reference Wizemann V, Lotz C, Techert F, Uthoff S: On-line hemodiafiltration versus low-flux hemodialysis. A prospective randomized study. Nephrol Dial Transplant. 2000, 15 (1): 43-48. 10.1093/ndt/15.1.43.CrossRefPubMed Wizemann V, Lotz C, Techert F, Uthoff S: On-line hemodiafiltration versus low-flux hemodialysis. A prospective randomized study. Nephrol Dial Transplant. 2000, 15 (1): 43-48. 10.1093/ndt/15.1.43.CrossRefPubMed
43.
go back to reference Ward RA, Schmidt B, Hullin J, Hillebrand GF, Samtleben W: A comparison of on-line hemodiafiltration and high-flux hemodialysis: a prospective clinical study. J Am Soc Nephrol. 2000, 11: 2344-2350.PubMed Ward RA, Schmidt B, Hullin J, Hillebrand GF, Samtleben W: A comparison of on-line hemodiafiltration and high-flux hemodialysis: a prospective clinical study. J Am Soc Nephrol. 2000, 11: 2344-2350.PubMed
44.
go back to reference Drechsler C, Pilz S, Obermayer-Pietsch B, Verduijn M, Tomaschitz A, Krane V, Espe K, Dekker F, Brandenburg V, März W, Ritz E, Wanner C: Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in hemodialysis patients. Eur Heart J. 2010, 31: 2253-2261. 10.1093/eurheartj/ehq246.CrossRefPubMedPubMedCentral Drechsler C, Pilz S, Obermayer-Pietsch B, Verduijn M, Tomaschitz A, Krane V, Espe K, Dekker F, Brandenburg V, März W, Ritz E, Wanner C: Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in hemodialysis patients. Eur Heart J. 2010, 31: 2253-2261. 10.1093/eurheartj/ehq246.CrossRefPubMedPubMedCentral
45.
go back to reference Wolf M, Shah A, Gutierrez O, Ankers E, Monroy M, Tamez H, Steele D, Chang Y, Camargo CA, Tonelli M, Thadhani R: Vitamin D levels and early mortality among incident hemodialysis patients. Kidney Int. 2007, 72: 1004-1013. 10.1038/sj.ki.5002451.CrossRefPubMed Wolf M, Shah A, Gutierrez O, Ankers E, Monroy M, Tamez H, Steele D, Chang Y, Camargo CA, Tonelli M, Thadhani R: Vitamin D levels and early mortality among incident hemodialysis patients. Kidney Int. 2007, 72: 1004-1013. 10.1038/sj.ki.5002451.CrossRefPubMed
46.
go back to reference Moe SM, Chertow GM, Coburn JW, Quarles LD, Goodman WG, Block GA, Drüeke TB, Cunningham J, Sherrard DJ, McCary LC, Olson KA, Turner SA, Martin KJ: Achieving NKF-K/DOQI bone metabolism and disease treatment goals with cinacalcet HCl. Kidney Int. 2005, 67: 760-771. 10.1111/j.1523-1755.2005.67139.x.CrossRefPubMed Moe SM, Chertow GM, Coburn JW, Quarles LD, Goodman WG, Block GA, Drüeke TB, Cunningham J, Sherrard DJ, McCary LC, Olson KA, Turner SA, Martin KJ: Achieving NKF-K/DOQI bone metabolism and disease treatment goals with cinacalcet HCl. Kidney Int. 2005, 67: 760-771. 10.1111/j.1523-1755.2005.67139.x.CrossRefPubMed
47.
go back to reference Block GA, Zaun D, Smits G, Persky M, Brillhart S, Nieman K, Liu J, St Peter WL: Cinacalcet hydrochloride treatment significantly improves all-cause and cardiovascular survival in a large cohort of hemodialysis patients. Kidney Int. 2010, 78: 578-589. 10.1038/ki.2010.167.CrossRefPubMed Block GA, Zaun D, Smits G, Persky M, Brillhart S, Nieman K, Liu J, St Peter WL: Cinacalcet hydrochloride treatment significantly improves all-cause and cardiovascular survival in a large cohort of hemodialysis patients. Kidney Int. 2010, 78: 578-589. 10.1038/ki.2010.167.CrossRefPubMed
48.
go back to reference The EVOLVE Trial Investigators: Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis. NEJM. 2012, EPub ahead og print The EVOLVE Trial Investigators: Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis. NEJM. 2012, EPub ahead og print
49.
go back to reference Cheung AK, Rocco MV, Yan G, Leypoldt JK, Levin NW, Greene T, Agodoa L, Bailey J, Beck GJ, Clark W, Levey AS, Ornt DB, Schulman G, Schwab S, Teehan B, Eknoyan G: Serum beta-2 microglobulin levels predict mortality in dialysis patients: results of the HEMO study. J Am Soc Nephrol. 2006, 17: 546-55. 10.1681/ASN.2005020132.CrossRefPubMed Cheung AK, Rocco MV, Yan G, Leypoldt JK, Levin NW, Greene T, Agodoa L, Bailey J, Beck GJ, Clark W, Levey AS, Ornt DB, Schulman G, Schwab S, Teehan B, Eknoyan G: Serum beta-2 microglobulin levels predict mortality in dialysis patients: results of the HEMO study. J Am Soc Nephrol. 2006, 17: 546-55. 10.1681/ASN.2005020132.CrossRefPubMed
50.
go back to reference Maduell F, Navarro V, Cruz MC, Torregrosa E, Garcia D, Simon V, Ferrero JA: Osteocalcin and myoglobin removal in on-line hemodiafiltration versus low- and high-flux hemodialysis. Am J Kidney Dis. 2002, 40: 582-9. 10.1053/ajkd.2002.34918.CrossRefPubMed Maduell F, Navarro V, Cruz MC, Torregrosa E, Garcia D, Simon V, Ferrero JA: Osteocalcin and myoglobin removal in on-line hemodiafiltration versus low- and high-flux hemodialysis. Am J Kidney Dis. 2002, 40: 582-9. 10.1053/ajkd.2002.34918.CrossRefPubMed
51.
go back to reference Maduell F, Navarro V, Torregrosa E, Rius A, Dicenta F, Cruz MC, Ferrero JA: Change from three times a week on-line hemodiafiltration to short daily on-line hemodiafiltration. Kidney Int. 2003, 64: 305-13. 10.1046/j.1523-1755.2003.00043.x.CrossRefPubMed Maduell F, Navarro V, Torregrosa E, Rius A, Dicenta F, Cruz MC, Ferrero JA: Change from three times a week on-line hemodiafiltration to short daily on-line hemodiafiltration. Kidney Int. 2003, 64: 305-13. 10.1046/j.1523-1755.2003.00043.x.CrossRefPubMed
52.
go back to reference Tisler A, Akocsi K, Borbas B, Fazakas L, Ferenczi L, Görögh S, Kulcsar I, Löcsey L, Samik J, Solt I, Szegedi J, Toth E, Wagner G, Kiss I: The effect of frequent or occasional dialysis-associated hypotension on survival of patients on maintenance hemodialysis. Nephrol Dial Transplant. 2003, 18: 2601-5. 10.1093/ndt/gfg450.CrossRefPubMed Tisler A, Akocsi K, Borbas B, Fazakas L, Ferenczi L, Görögh S, Kulcsar I, Löcsey L, Samik J, Solt I, Szegedi J, Toth E, Wagner G, Kiss I: The effect of frequent or occasional dialysis-associated hypotension on survival of patients on maintenance hemodialysis. Nephrol Dial Transplant. 2003, 18: 2601-5. 10.1093/ndt/gfg450.CrossRefPubMed
53.
go back to reference Selby NM, McIntyre CW: A systematic review of the clinical effects of reducing dialysate fluid temperature. Nephrol Dial Transplant. 2006, 21: 1883-98. 10.1093/ndt/gfl126.CrossRefPubMed Selby NM, McIntyre CW: A systematic review of the clinical effects of reducing dialysate fluid temperature. Nephrol Dial Transplant. 2006, 21: 1883-98. 10.1093/ndt/gfl126.CrossRefPubMed
54.
go back to reference Donauer J, Schweiger C, Rumberger B, Krumme B, Böhler J: Reduction of hypotensive side effects during online-hemodiafiltration and low temperature hemodialysis. Nephrol Dial Transplant. 2003, 18: 1616-22. 10.1093/ndt/gfg206.CrossRefPubMed Donauer J, Schweiger C, Rumberger B, Krumme B, Böhler J: Reduction of hypotensive side effects during online-hemodiafiltration and low temperature hemodialysis. Nephrol Dial Transplant. 2003, 18: 1616-22. 10.1093/ndt/gfg206.CrossRefPubMed
55.
go back to reference Kooman J, Basci A, Pizzarelli F, Canaud B, Haage P, Fouque D, Konner K, Martin-Malo A, Pedrini L, Tattersall J, Tordoir J, Vennegoor M, Wanner C, ter Wee P, Vanholder R: EBPG guideline on hemodynamic instability. Nephrol Dial Transplant. 2007, 22 (Suppl 2): ii22-44.PubMed Kooman J, Basci A, Pizzarelli F, Canaud B, Haage P, Fouque D, Konner K, Martin-Malo A, Pedrini L, Tattersall J, Tordoir J, Vennegoor M, Wanner C, ter Wee P, Vanholder R: EBPG guideline on hemodynamic instability. Nephrol Dial Transplant. 2007, 22 (Suppl 2): ii22-44.PubMed
Metadata
Title
Monitoring of hemodialysis quality-of-care indicators: why is it important?
Authors
Steven Grangé
Mélanie Hanoy
Frank Le Roy
Dominique Guerrot
Michel Godin
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Nephrology / Issue 1/2013
Electronic ISSN: 1471-2369
DOI
https://doi.org/10.1186/1471-2369-14-109

Other articles of this Issue 1/2013

BMC Nephrology 1/2013 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.