Published in:
01-02-2012 | Cardiac Molecular Imaging (F Jaffer, Section Editor)
Molecular Imaging of Macrophages in Atherosclerosis
Authors:
Elena Aikawa, Sophie E. P. New, Tetsuro Miyazaki, Daiju Fukuda, Masanori Aikawa
Published in:
Current Cardiovascular Imaging Reports
|
Issue 1/2012
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Abstract
Macrophages contribute to the initiation, progression, and acute complications of atherosclerosis. Imaging of macrophages during disease progression provides new insights into the mechanisms of atherosclerosis. Advanced imaging techniques may serve as sensitive diagnostic tools for early detection of the disease to identify individuals with subclinical plaques and to prevent devastating complications. Furthermore, molecular imaging may monitor the effects of therapeutic interventions. Development of fully integrated molecular imaging requires dynamic multidisciplinary collaboration.