Molecular Imaging and Biology

Firing Up the Innovation Engine

SNIDD Special Issue

H. Donald Burns, Richard A. Frank, Rikki Waterhouse

Molecular Imaging in Drug Discovery and Development: Potential and Limitations of Nonnuclear Methods

Markus Rudin, Martin Rausch, Markus Stoeckli

What Has Intrinsic Signal Optical Imaging Taught Us About NGF-Induced Rapid Plasticity in Adult Cortex and Its Relationship to the Cholinergic System?

Neal Prakash, Ron D. Frostig

Noninvasive Imaging of Cardiac Gene Expression and Its Future Implications for Molecular Therapy

Frank M. Bengel

Weaving Single Photon Imaging into New Drug Development

P. David Mozley

Positron Emission Tomography Studies on Binding of Central Nervous System Drugs and P-Glycoprotein Function in the Rodent Brain

Philip H. Elsinga, N. Harry Hendrikse, Joost Bart, Aren van Waarde, Willem Vaalburg

Imaging the Dopamine System with In Vivo [11C]raclopride Displacement Studies: Understanding the True Mechanism

Nathalie Ginovart

Positron Emission Tomography Imaging of Small Animals in Anticancer Drug Development

Eric O. Aboagye

Toward the Validation of Functional Neuroimaging as a Potential Biomarker for Alzheimer’s Disease: Implications for Drug Development

Alberto Pupi, Lisa Mosconi, Flavio M. Nobili, Sandro Sorbi

A Computational Positron Emission Tomography Simulation Model for Imaging β-Amyloid in Mice

Melvin K. Simmons, Ravindra Manjeshwar, Eric D. Agdeppa, Robert M. Mattheyses, Thomas R. Kiehl, Michael C. Montalto