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Published in: Archives of Virology 9/2011

01-09-2011 | Brief Report

Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005–2007

Authors: Ying-chun Dai, Gui-fang Hu, Xu-fu Zhang, Can-lei Song, Wen-long Xiang, Xian-bo Wu, Le-yi Wang, Xi Jiang, Jun Nie

Published in: Archives of Virology | Issue 9/2011

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Abstract

Human noroviruses (NoVs) are an important cause of epidemic acute gastroenteritis. Their role in sporadic cases, however, is less clear. In this study, we performed a two-year surveillance (September 2005 to August 2007) of NoV gastroenteritis in outpatient clinics in a southern city of China, Jiangmen City. NoVs were detected in 115 patients (115/881, 13.1%) with 30 (26.1%) co-infections with rotaviruses. Sequence analysis showed that all 115 NoVs belonged to genogroup II, with GII.4 being the most predominant (87.8%). NoV-associated infection can be seen year-around, with autumn and winter peaks. This study provides basic information on sporadic cases of major NoV gastroenteritis in children in different seasons, which is valuable for future disease control and prevention.
Literature
1.
go back to reference Bon F, Ambert-Balay K, Giraudon H, Kaplon J, Le Guyader S, Pommepuy M, Gallay A, Vaillant V, de Valk H, Chikhi-Brachet R, Flahaut A, Pothier P, Kohli E (2005) Molecular epidemiology of caliciviruses detected in sporadic and outbreak cases of gastroenteritis in France from December 1998 to February 2004. J Clin Microbiol 43:4659–4664PubMedCrossRef Bon F, Ambert-Balay K, Giraudon H, Kaplon J, Le Guyader S, Pommepuy M, Gallay A, Vaillant V, de Valk H, Chikhi-Brachet R, Flahaut A, Pothier P, Kohli E (2005) Molecular epidemiology of caliciviruses detected in sporadic and outbreak cases of gastroenteritis in France from December 1998 to February 2004. J Clin Microbiol 43:4659–4664PubMedCrossRef
3.
go back to reference Cheng WX, Ye XH, Yang XM, Li YN, Jin M, Jin Y, Duan ZJ (2010) Epidemiological study of human calicivirus infection in children with gastroenteritis in Lanzhou from 2001 to 2007. Arch Virol 155:553–555PubMedCrossRef Cheng WX, Ye XH, Yang XM, Li YN, Jin M, Jin Y, Duan ZJ (2010) Epidemiological study of human calicivirus infection in children with gastroenteritis in Lanzhou from 2001 to 2007. Arch Virol 155:553–555PubMedCrossRef
4.
go back to reference Chhabra P, Dhongade RK, Kalrao VR, Bavdekar AR, Chitambar SD (2009) Epidemiological, clinical, and molecular features of norovirus infections in western India. J Med Virol 81:922–932PubMedCrossRef Chhabra P, Dhongade RK, Kalrao VR, Bavdekar AR, Chitambar SD (2009) Epidemiological, clinical, and molecular features of norovirus infections in western India. J Med Virol 81:922–932PubMedCrossRef
5.
go back to reference Chhabra P, Walimbe AM, Chitambar SD (2010) Molecular characterization of three novel intergenotype norovirus GII recombinant strains from western India. Virus Res 147:242–246PubMedCrossRef Chhabra P, Walimbe AM, Chitambar SD (2010) Molecular characterization of three novel intergenotype norovirus GII recombinant strains from western India. Virus Res 147:242–246PubMedCrossRef
6.
go back to reference Dai YC, Nie J, Zhang XF, Li ZF, Bai Y, Zeng ZR, Yu SY, Farkas T, Jiang X (2004) Seroprevalence of antibodies against noroviruses among students in a Chinese military medical university. J Clin Microbiol 42:4615–4619PubMedCrossRef Dai YC, Nie J, Zhang XF, Li ZF, Bai Y, Zeng ZR, Yu SY, Farkas T, Jiang X (2004) Seroprevalence of antibodies against noroviruses among students in a Chinese military medical university. J Clin Microbiol 42:4615–4619PubMedCrossRef
7.
go back to reference Dai YC, Xia M, Zhan HC, Liu Y, Li JD, Chen Q, Yu SY, Nie J, Farkas T, Jiang X (2010) Surveillance and risk factors of norovirus gastroenteritis among children in a southern city of China in the fall-winter seasons of 2003–2006. J Paediatr Child Health 46:45–50PubMedCrossRef Dai YC, Xia M, Zhan HC, Liu Y, Li JD, Chen Q, Yu SY, Nie J, Farkas T, Jiang X (2010) Surveillance and risk factors of norovirus gastroenteritis among children in a southern city of China in the fall-winter seasons of 2003–2006. J Paediatr Child Health 46:45–50PubMedCrossRef
8.
go back to reference Dey SK, Phan TG, Mizuguchia M, Okitsua S, Ushijima H (2010) Novel recombinant norovirus in Japan. Virus Genes 40:362–364PubMedCrossRef Dey SK, Phan TG, Mizuguchia M, Okitsua S, Ushijima H (2010) Novel recombinant norovirus in Japan. Virus Genes 40:362–364PubMedCrossRef
9.
go back to reference Eden JS, Bull RA, Tu E, McIver CJ, Lyon MJ, Marshall JA, Smith DW, Musto J, Rawlinson WD, White PA (2010) Norovirus GII.4 variant 2006b caused epidemics of acute gastroenteritis in Australia during 2007 and 2008. J Clin Virol 49:265–271PubMedCrossRef Eden JS, Bull RA, Tu E, McIver CJ, Lyon MJ, Marshall JA, Smith DW, Musto J, Rawlinson WD, White PA (2010) Norovirus GII.4 variant 2006b caused epidemics of acute gastroenteritis in Australia during 2007 and 2008. J Clin Virol 49:265–271PubMedCrossRef
10.
go back to reference Ferreira MS, Victoria M, Carvalho-Costa FA, Vieira CB, Xavier MP, Fioretti JM, Andrade J, Volotao EM, Rocha M, Leite JP, Miagostovich MP (2010) Surveillance of norovirus infections in the state of Rio De Janeiro, Brazil 2005–2008. J Med Virol 82:1442–1448PubMedCrossRef Ferreira MS, Victoria M, Carvalho-Costa FA, Vieira CB, Xavier MP, Fioretti JM, Andrade J, Volotao EM, Rocha M, Leite JP, Miagostovich MP (2010) Surveillance of norovirus infections in the state of Rio De Janeiro, Brazil 2005–2008. J Med Virol 82:1442–1448PubMedCrossRef
11.
go back to reference Fukuda S, Sasaki Y, Takao S, Seno M (2008) Recombinant norovirus implicated in gastroenteritis outbreaks in Hiroshima Prefecture, Japan. J Med Virol 80:921–928PubMedCrossRef Fukuda S, Sasaki Y, Takao S, Seno M (2008) Recombinant norovirus implicated in gastroenteritis outbreaks in Hiroshima Prefecture, Japan. J Med Virol 80:921–928PubMedCrossRef
12.
go back to reference Guo L, Song J, Xu X, Ren L, Li J, Zhou H, Wang M, Qu J, Wang J, Hung T (2009) Genetic analysis of norovirus in children affected with acute gastroenteritis in Beijing, 2004–2007. J Clin Virol 44:94–98PubMedCrossRef Guo L, Song J, Xu X, Ren L, Li J, Zhou H, Wang M, Qu J, Wang J, Hung T (2009) Genetic analysis of norovirus in children affected with acute gastroenteritis in Beijing, 2004–2007. J Clin Virol 44:94–98PubMedCrossRef
13.
14.
go back to reference Jiang X, Wang M, Graham DY, Estes MK (1992) Expression, self-assembly, and antigenicity of the Norwalk virus capsid protein. J Virol 66:6527–6532PubMed Jiang X, Wang M, Graham DY, Estes MK (1992) Expression, self-assembly, and antigenicity of the Norwalk virus capsid protein. J Virol 66:6527–6532PubMed
15.
go back to reference Jin M, Xie HP, Duan ZJ, Liu N, Zhang Q, Wu BS, Li HY, Cheng WX, Yang SH, Yu JM (2008) Emergence of the GII4/2006b variant and recombinant noroviruses in China. J Med Virol 80:1997–2004PubMedCrossRef Jin M, Xie HP, Duan ZJ, Liu N, Zhang Q, Wu BS, Li HY, Cheng WX, Yang SH, Yu JM (2008) Emergence of the GII4/2006b variant and recombinant noroviruses in China. J Med Virol 80:1997–2004PubMedCrossRef
16.
go back to reference Jin Y, Cheng WX, Yang XM, Jin M, Zhang Q, Xu ZQ, Yu JM, Zhu L, Yang SH, Liu N, Cui SX, Fang ZY, Duan ZJ (2009) Viral agents associated with acute gastroenteritis in children hospitalized with diarrhea in Lanzhou, China. J Clin Virol 44:238–241PubMedCrossRef Jin Y, Cheng WX, Yang XM, Jin M, Zhang Q, Xu ZQ, Yu JM, Zhu L, Yang SH, Liu N, Cui SX, Fang ZY, Duan ZJ (2009) Viral agents associated with acute gastroenteritis in children hospitalized with diarrhea in Lanzhou, China. J Clin Virol 44:238–241PubMedCrossRef
17.
go back to reference Katayama K, Shirato-Horikoshi H, Kojima S, Kageyama T, Oka T, Hoshino F, Fukushi S, Shinohara M, Uchida K, Suzuki Y, Gojobori T, Takeda N (2002) Phylogenetic analysis of the complete genome of 18 Norwalk-like viruses. Virology 299:225–239PubMedCrossRef Katayama K, Shirato-Horikoshi H, Kojima S, Kageyama T, Oka T, Hoshino F, Fukushi S, Shinohara M, Uchida K, Suzuki Y, Gojobori T, Takeda N (2002) Phylogenetic analysis of the complete genome of 18 Norwalk-like viruses. Virology 299:225–239PubMedCrossRef
18.
go back to reference Khamrin P, Maneekarn N, Thongprachum A, Chaimongkol N, Okitsu S, Ushijima H (2010) Emergence of new norovirus variants and genetic heterogeneity of noroviruses and sapoviruses in children admitted to hospital with diarrhea in Thailand. J Med Virol 82:289–296PubMedCrossRef Khamrin P, Maneekarn N, Thongprachum A, Chaimongkol N, Okitsu S, Ushijima H (2010) Emergence of new norovirus variants and genetic heterogeneity of noroviruses and sapoviruses in children admitted to hospital with diarrhea in Thailand. J Med Virol 82:289–296PubMedCrossRef
19.
go back to reference Kojima S, Kageyama T, Fukushi S, Hoshino FB, Shinohara M, Uchida K, Natori K, Takeda N, Katayama K (2002) Genogroup-specific PCR primers for detection of Norwalk-like viruses. J Virol Methods 100:107–114PubMedCrossRef Kojima S, Kageyama T, Fukushi S, Hoshino FB, Shinohara M, Uchida K, Natori K, Takeda N, Katayama K (2002) Genogroup-specific PCR primers for detection of Norwalk-like viruses. J Virol Methods 100:107–114PubMedCrossRef
20.
go back to reference Li H, Mo YL, Ke CW, Zheng HZ, Zhou XH, Guo RN, Chen QX, Fang L, Zou LR (2010) Molecular epidemiological characteristics of norovirus gastroenteritis outbreaks in Guangdong from 2005 to 2008. Bing Du Xue Bao 26:202–207PubMed Li H, Mo YL, Ke CW, Zheng HZ, Zhou XH, Guo RN, Chen QX, Fang L, Zou LR (2010) Molecular epidemiological characteristics of norovirus gastroenteritis outbreaks in Guangdong from 2005 to 2008. Bing Du Xue Bao 26:202–207PubMed
21.
go back to reference Lindesmith LC, Donaldson EF, Lobue AD, Cannon JL, Zheng DP, Vinje J, Baric RS (2008) Mechanisms of GII.4 norovirus persistence in human populations. PLoS Med 5:e31PubMedCrossRef Lindesmith LC, Donaldson EF, Lobue AD, Cannon JL, Zheng DP, Vinje J, Baric RS (2008) Mechanisms of GII.4 norovirus persistence in human populations. PLoS Med 5:e31PubMedCrossRef
22.
go back to reference Liu C, Grillner L, Jonsson K, Linde A, Shen K, Lindell AT, Wirgart BZ, Johansen K (2006) Identification of viral agents associated with diarrhea in young children during a winter season in Beijing, China. J Clin Virol 35:69–72PubMedCrossRef Liu C, Grillner L, Jonsson K, Linde A, Shen K, Lindell AT, Wirgart BZ, Johansen K (2006) Identification of viral agents associated with diarrhea in young children during a winter season in Beijing, China. J Clin Virol 35:69–72PubMedCrossRef
23.
go back to reference Lole KS, Bollinger RC, Paranjape RS, Gadkari D, Kulkarni SS, Novak NG, Ingersoll R, Sheppard HW, Ray SC (1999) Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. J Virol 73:152–160PubMed Lole KS, Bollinger RC, Paranjape RS, Gadkari D, Kulkarni SS, Novak NG, Ingersoll R, Sheppard HW, Ray SC (1999) Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. J Virol 73:152–160PubMed
24.
go back to reference Marshall JA, Hellard ME, Sinclair MI, Fairley CK, Cox BJ, Catton MG, Kelly H, Wright PJ (2003) Incidence and characteristics of endemic Norwalk-like virus-associated gastroenteritis. J Med Virol 69:568–578PubMedCrossRef Marshall JA, Hellard ME, Sinclair MI, Fairley CK, Cox BJ, Catton MG, Kelly H, Wright PJ (2003) Incidence and characteristics of endemic Norwalk-like virus-associated gastroenteritis. J Med Virol 69:568–578PubMedCrossRef
25.
go back to reference Motomura K, Oka T, Yokoyama M, Nakamura H, Mori H, Ode H, Hansman GS, Katayama K, Kanda T, Tanaka T, Takeda N, Sato H (2008) Identification of monomorphic and divergent haplotypes in the 2006–2007 norovirus GII/4 epidemic population by genome wide tracing of evolutionary history. J Virol 82:11247–11262PubMedCrossRef Motomura K, Oka T, Yokoyama M, Nakamura H, Mori H, Ode H, Hansman GS, Katayama K, Kanda T, Tanaka T, Takeda N, Sato H (2008) Identification of monomorphic and divergent haplotypes in the 2006–2007 norovirus GII/4 epidemic population by genome wide tracing of evolutionary history. J Virol 82:11247–11262PubMedCrossRef
26.
go back to reference Nayak MK, Balasubramanian G, Sahoo GC, Bhattacharya R, Vinje J, Kobayashi N, Sarkar MC, Bhattacharya MK, Krishnan T (2008) Detection of a novel intergenogroup recombinant Norovirus from Kolkata, India. Virology 377:117–123PubMedCrossRef Nayak MK, Balasubramanian G, Sahoo GC, Bhattacharya R, Vinje J, Kobayashi N, Sarkar MC, Bhattacharya MK, Krishnan T (2008) Detection of a novel intergenogroup recombinant Norovirus from Kolkata, India. Virology 377:117–123PubMedCrossRef
27.
go back to reference Nayak MK, Chatterjee D, Nataraju SM, Pativada M, Mitra U, Chatterjee MK, Saha TK, Sarkar U, Krishnan T (2009) A new variant of Norovirus GII.4/2007 and inter-genotype recombinant strains of NVGII causing acute watery diarrhoea among children in Kolkata, India. J Clin Virol 45:223–229PubMedCrossRef Nayak MK, Chatterjee D, Nataraju SM, Pativada M, Mitra U, Chatterjee MK, Saha TK, Sarkar U, Krishnan T (2009) A new variant of Norovirus GII.4/2007 and inter-genotype recombinant strains of NVGII causing acute watery diarrhoea among children in Kolkata, India. J Clin Virol 45:223–229PubMedCrossRef
28.
go back to reference Nenonen NP, Hannoun C, Olsson MB, Bergstrom T (2009) Molecular analysis of an oyster-related norovirus outbreak. J Clin Virol 45:105–108PubMedCrossRef Nenonen NP, Hannoun C, Olsson MB, Bergstrom T (2009) Molecular analysis of an oyster-related norovirus outbreak. J Clin Virol 45:105–108PubMedCrossRef
29.
go back to reference Nguyen TA, Yagyu F, Okame M, Phan TG, Trinh QD, Yan H, Hoang KT, Cao AT, Le Hoang P, Okitsu S, Ushijima H (2007) Diversity of viruses associated with acute gastroenteritis in children hospitalized with diarrhea in Ho Chi Minh City, Vietnam. J Med Virol 79:582–590PubMedCrossRef Nguyen TA, Yagyu F, Okame M, Phan TG, Trinh QD, Yan H, Hoang KT, Cao AT, Le Hoang P, Okitsu S, Ushijima H (2007) Diversity of viruses associated with acute gastroenteritis in children hospitalized with diarrhea in Ho Chi Minh City, Vietnam. J Med Virol 79:582–590PubMedCrossRef
30.
go back to reference Patel MM, Widdowson MA, Glass RI, Akazawa K, Vinje J, Parashar UD (2008) Systematic literature review of role of noroviruses in sporadic gastroenteritis. Emerg Infect Dis 14:1224–1231PubMedCrossRef Patel MM, Widdowson MA, Glass RI, Akazawa K, Vinje J, Parashar UD (2008) Systematic literature review of role of noroviruses in sporadic gastroenteritis. Emerg Infect Dis 14:1224–1231PubMedCrossRef
31.
go back to reference Phan TG, Kaneshi K, Ueda Y, Nakaya S, Nishimura S, Yamamoto A, Sugita K, Takanashi S, Okitsu S, Ushijima H (2007) Genetic heterogeneity, evolution, and recombination in noroviruses. J Med Virol 79:1388–1400PubMedCrossRef Phan TG, Kaneshi K, Ueda Y, Nakaya S, Nishimura S, Yamamoto A, Sugita K, Takanashi S, Okitsu S, Ushijima H (2007) Genetic heterogeneity, evolution, and recombination in noroviruses. J Med Virol 79:1388–1400PubMedCrossRef
32.
go back to reference Pletneva MA, Sosnovtsev SV, Green KY (2001) The genome of Hawaii virus and its relationship with other members of the caliciviridae. Virus Genes 23:5–16PubMedCrossRef Pletneva MA, Sosnovtsev SV, Green KY (2001) The genome of Hawaii virus and its relationship with other members of the caliciviridae. Virus Genes 23:5–16PubMedCrossRef
33.
go back to reference Sdiri-Loulizi K, Ambert-Balay K, Gharbi-Khelifi H, Sakly N, Hassine M, Chouchane S, Guediche MN, Pothier P, Aouni M (2009) Molecular epidemiology of norovirus gastroenteritis investigated using samples collected from children in Tunisia during a four-year period: detection of the norovirus variant GGII.4 Hunter as early as January 2003. J Clin Microbiol 47:421–429PubMedCrossRef Sdiri-Loulizi K, Ambert-Balay K, Gharbi-Khelifi H, Sakly N, Hassine M, Chouchane S, Guediche MN, Pothier P, Aouni M (2009) Molecular epidemiology of norovirus gastroenteritis investigated using samples collected from children in Tunisia during a four-year period: detection of the norovirus variant GGII.4 Hunter as early as January 2003. J Clin Microbiol 47:421–429PubMedCrossRef
34.
go back to reference Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599PubMedCrossRef Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24:1596–1599PubMedCrossRef
35.
go back to reference ter Waarbeek HL, Dukers-Muijrers NH, Vennema H, Hoebe CJ (2010) Waterborne gastroenteritis outbreak at a scouting camp caused by two norovirus genogroups: GI and GII. J Clin Virol 47:268–272PubMedCrossRef ter Waarbeek HL, Dukers-Muijrers NH, Vennema H, Hoebe CJ (2010) Waterborne gastroenteritis outbreak at a scouting camp caused by two norovirus genogroups: GI and GII. J Clin Virol 47:268–272PubMedCrossRef
36.
go back to reference Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876–4882PubMedCrossRef Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG (1997) The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876–4882PubMedCrossRef
37.
go back to reference Tseng FC, Leon JS, MacCormack JN, Maillard JM, Moe CL (2007) Molecular epidemiology of norovirus gastroenteritis outbreaks in North Carolina, United States: 1995–2000. J Med Virol 79:84–91PubMedCrossRef Tseng FC, Leon JS, MacCormack JN, Maillard JM, Moe CL (2007) Molecular epidemiology of norovirus gastroenteritis outbreaks in North Carolina, United States: 1995–2000. J Med Virol 79:84–91PubMedCrossRef
38.
go back to reference Vinje J, Koopmans MP (1996) Molecular detection and epidemiology of small round-structured viruses in outbreaks of gastroenteritis in the Netherlands. J Infect Dis 174:610–615PubMedCrossRef Vinje J, Koopmans MP (1996) Molecular detection and epidemiology of small round-structured viruses in outbreaks of gastroenteritis in the Netherlands. J Infect Dis 174:610–615PubMedCrossRef
39.
go back to reference Wadl M, Scherer K, Nielsen S, Diedrich S, Ellerbroek L, Frank C, Gatzer R, Hoehne M, Johne R, Klein G, Koch J, Schulenburg J, Thielbein U, Stark K, Bernard H (2010) Food-borne norovirus-outbreak at a military base, Germany, 2009. BMC Infect Dis 10:30PubMedCrossRef Wadl M, Scherer K, Nielsen S, Diedrich S, Ellerbroek L, Frank C, Gatzer R, Hoehne M, Johne R, Klein G, Koch J, Schulenburg J, Thielbein U, Stark K, Bernard H (2010) Food-borne norovirus-outbreak at a military base, Germany, 2009. BMC Infect Dis 10:30PubMedCrossRef
40.
go back to reference Wu FT, Oka T, Katayama K, Wu HS, Donald JD, Miyamura T, Takeda N, Hansman GS (2006) Genetic diversity of noroviruses in Taiwan between November 2004 and March 2005. Arch Virol 151:1319–1327PubMedCrossRef Wu FT, Oka T, Katayama K, Wu HS, Donald JD, Miyamura T, Takeda N, Hansman GS (2006) Genetic diversity of noroviruses in Taiwan between November 2004 and March 2005. Arch Virol 151:1319–1327PubMedCrossRef
41.
go back to reference Xu J, Yang Y, Sun J, Ding Y (2009) Molecular epidemiology of norovirus infection among children with acute gastroenteritis in Shanghai, China, 2001–2005. J Med Virol 81:1826–1830PubMedCrossRef Xu J, Yang Y, Sun J, Ding Y (2009) Molecular epidemiology of norovirus infection among children with acute gastroenteritis in Shanghai, China, 2001–2005. J Med Virol 81:1826–1830PubMedCrossRef
42.
go back to reference Yang Y, Xia M, Tan M, Huang P, Zhong W, Pang XL, Lee BE, Meller J, Wang T, Jiang X (2010) Genetic and phenotypic characterization of GII-4 noroviruses that circulated during 1987 to 2008. J Virol 84:9595–9607PubMedCrossRef Yang Y, Xia M, Tan M, Huang P, Zhong W, Pang XL, Lee BE, Meller J, Wang T, Jiang X (2010) Genetic and phenotypic characterization of GII-4 noroviruses that circulated during 1987 to 2008. J Virol 84:9595–9607PubMedCrossRef
43.
go back to reference Yoon JS, Lee SG, Hong SK, Lee SA, Jheong WH, Oh SS, Oh MH, Ko GP, Lee CH, Paik SY (2008) Molecular epidemiology of norovirus infections in children with acute gastroenteritis in South Korea in November 2005 through November 2006. J Clin Microbiol 46:1474–1477PubMedCrossRef Yoon JS, Lee SG, Hong SK, Lee SA, Jheong WH, Oh SS, Oh MH, Ko GP, Lee CH, Paik SY (2008) Molecular epidemiology of norovirus infections in children with acute gastroenteritis in South Korea in November 2005 through November 2006. J Clin Microbiol 46:1474–1477PubMedCrossRef
44.
go back to reference Zheng DP, Ando T, Fankhauser RL, Beard RS, Glass RI, Monroe SS (2006) Norovirus classification and proposed strain nomenclature. Virology 346:312–323PubMedCrossRef Zheng DP, Ando T, Fankhauser RL, Beard RS, Glass RI, Monroe SS (2006) Norovirus classification and proposed strain nomenclature. Virology 346:312–323PubMedCrossRef
Metadata
Title
Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005–2007
Authors
Ying-chun Dai
Gui-fang Hu
Xu-fu Zhang
Can-lei Song
Wen-long Xiang
Xian-bo Wu
Le-yi Wang
Xi Jiang
Jun Nie
Publication date
01-09-2011
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 9/2011
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-011-1010-3

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