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Published in: European Spine Journal 11/2012

01-11-2012 | Original Article

Modic type I changes and recovery of back pain after lumbar microdiscectomy

Authors: Andreas Sørlie, Viggo Moholdt, Kjell Arne Kvistad, Øystein P. Nygaard, Tor Ingebrigtsen, Trond Iversen, Roar Kloster, Tore K. Solberg

Published in: European Spine Journal | Issue 11/2012

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Abstract

Purpose

To investigate whether the presence of Modic changes type I (MC I) found on preoperative MRI scans represent a risk factor for persistent back pain 12 months after surgery amongst patients operated for lumbar disc herniation.

Methods

Cohort study of 178 consecutive patients operated with lumbar microdiscectomy. Preoperative MRI scans were evaluated by two independent neuroradiologists. Primary outcome measure was the visual analogue scale (VAS) for back pain. Secondary outcome measures were; VAS for leg pain, physical function (Oswestry Disability Index), and health-related quality of life (EQ-5D), self-reported benefit of the operation and employment status. The presence of MC I was used as exposition variable and adjusted for other risk factors in multivariate analyses.

Results

The Modic classification showed a high inter-observer reproducibility. Patients with MC I had less improvement of back pain 12 months after surgery, compared to those who had no or other types of MC, but this negative association no longer showed statistical significance when adjusted for smoking, which remained the only independent risk factor for persistent back pain.

Conclusions

Patients with preoperative MC I can expect less but still significant improvement of back pain 1 year after microdiscectomy, but not if they smoke cigarettes.
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Metadata
Title
Modic type I changes and recovery of back pain after lumbar microdiscectomy
Authors
Andreas Sørlie
Viggo Moholdt
Kjell Arne Kvistad
Øystein P. Nygaard
Tor Ingebrigtsen
Trond Iversen
Roar Kloster
Tore K. Solberg
Publication date
01-11-2012
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue 11/2012
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-012-2419-4

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