Published in:
Open Access
01-12-2010 | Poster presentation
Minority M184V variants in women exposed to 3TC/FTC-containing lopinavir-ritonavir (LPVr) regimens in pregnancy
Authors:
S Surah, S Oshea, S Costelloe, M Hanlon, J Mullen, I Chrystie, GP Taylor, A De Ruiter
Published in:
Journal of the International AIDS Society
|
Special Issue 4/2010
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Excerpt
Short-term antiretroviral therapy (START) consisting of 2 NRTIs and a ritonavir boosted PI is widely used in pregnancy. Resistance is rarely detected using population based sequencing. The aim of this study was to determine whether minority M184V variants emerge with 3TC/FTC containing START regimens in pregnancy and if so whether this impacted upon future treatment outcomes. …