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01-04-2020 | Review Article

Mini review–vanadium-induced neurotoxicity and possible targets

Authors: Madhuri Ramji Jaiswal, Pravin Popatrao Kale

Published in: Neurological Sciences | Issue 4/2020

Abstract

Vanadium, a transition metal, ubiquitous in nature is known to have therapeutic effect as well as toxic effect. It is known to possess antidiabetic, antitumor and antiparasitic activity. However, on long term exposure, it produces neurotoxicity which may result in memory impairment. The possible mechanism known to cause neurotoxicity suggested is oxidative stress and inflammation of neuronal cells. The present review has focused on discussing the role of protein P38 mitogen-activated protein kinase and oxidative stress as possible targets to treat vanadium-induced neurotoxicity.

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Title: Mini review–vanadium-induced neurotoxicity and possible targets
Authors: Madhuri Ramji Jaiswal
Pravin Popatrao Kale
Publication date: 01-04-2020
Publisher: Springer International Publishing
Published in: Neurological Sciences / Issue 4/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-019-04188-5

At a glance: The STEP trials

Springer Medicine

Mini review–vanadium-induced neurotoxicity and possible targets

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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