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Published in: BMC Gastroenterology 1/2023

Open Access 01-12-2023 | Milligan-Morgan Hemorrhoidectomy | Research

Milligan-Morgan hemorrhoidectomy combined with non-doppler hemorrhoidal artery ligation for the treatment of grade III/IV hemorrhoids: a single centre retrospective study

Authors: Qing Long, Yong Wen, Jun Li

Published in: BMC Gastroenterology | Issue 1/2023

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Abstract

Background

Milligan-Morgan hemorrhoidectomy (MMH) is the most widely used surgical procedure because of its precise curative effect, but it has the disadvantages such as obvious postoperative pain and bleeding. To retrospectively evaluate the efficacy and safety of MMH combined with non-Doppler hemorrhoidal artery ligation (MMH + ND-HAL) for the treatment of grade III/IV hemorrhoids.

Methods

We conducted a retrospective analysis of 115 patients with grade III/IV hemorrhoids, 53 patients had received MMH + ND-HAL, and the remaining 62 patients received MMH. We collected and compared demographic and clinical characteristics of both groups, including intraoperative blood loss, postoperative visual analog scale (VAS) for pain, analgesic consumption, postoperative bleeding, perianal incision edema, urinary retention, anal stenosis, anal incontinence incidence, recurrence rate (prolapse or bleeding), and patient satisfaction.

Results

The VAS pain score of the first postoperative defecation and at the postoperative 12 h, 1 day, 2 days, 3 days, and 7 days, as well as the total analgesic consumption within 7 days, for the MMH + ND-HAL group were lower than those for the MMH group (P < 0.05). The intraoperative blood loss, the incidence of postoperative bleeding, perianal incision edema, and urinary retention in the MMH + ND-HAL group was lower than that in the MMH group (P < 0.05). No anal stenosis or anal incontinence occurred in either group. At follow-up by telephone or outpatient 12 months after surgery, the recurrence rate (prolapse or bleeding) was lower in the MMH + ND-HAL group than in the MMH group (P < 0.05), and satisfaction was higher in the MMH + ND-HAL group than in the MMH group (P < 0.05).

Conclusions

MMH + ND-HAL was a satisfactory surgical modality for treating III/IV hemorrhoids.
Literature
1.
go back to reference 1.Pata F, Sgrò A, Ferrara F, Vigorita V, Gallo G, Pellino G. Anatomy, physiology and pathophysiology of haemorrhoids. Rev Recent Clin Tria. 2021;16(1):75–80. 1.Pata F, Sgrò A, Ferrara F, Vigorita V, Gallo G, Pellino G. Anatomy, physiology and pathophysiology of haemorrhoids. Rev Recent Clin Tria. 2021;16(1):75–80.
3.
go back to reference Yamana T. Japanese practice guidelines for anal disorders I. hemorrhoids. J Anus Rectum Colon. 2017;1(3):89–99.CrossRefPubMed Yamana T. Japanese practice guidelines for anal disorders I. hemorrhoids. J Anus Rectum Colon. 2017;1(3):89–99.CrossRefPubMed
4.
go back to reference Sheikh P, Régnier C, Goron F, Salmat G. The prevalence, characteristics and treatment of hemorrhoidal disease: results of an international web-based survey. J Comp Effect Res. 2020;9(17):1219–32.CrossRef Sheikh P, Régnier C, Goron F, Salmat G. The prevalence, characteristics and treatment of hemorrhoidal disease: results of an international web-based survey. J Comp Effect Res. 2020;9(17):1219–32.CrossRef
5.
go back to reference Muldoon R. Review of american society of Colon and rectal Surgeons Clinical Practice Guidelines for the management of hemorrhoids. JAMA Surg. 2020;155(8):773–4.CrossRefPubMed Muldoon R. Review of american society of Colon and rectal Surgeons Clinical Practice Guidelines for the management of hemorrhoids. JAMA Surg. 2020;155(8):773–4.CrossRefPubMed
6.
go back to reference Koh FH, Foo FJ, Ho L, Sivarajah SS, Tan WJ, Chew MH. Study protocol for the use of conventional open haemorrhoidectomy versus laser haemorrhoidoplasty in the treatment of symptomatic haemorrhoids: a randomized controlled trial. Euro Surg Res. 2020;61(6):201–8.CrossRef Koh FH, Foo FJ, Ho L, Sivarajah SS, Tan WJ, Chew MH. Study protocol for the use of conventional open haemorrhoidectomy versus laser haemorrhoidoplasty in the treatment of symptomatic haemorrhoids: a randomized controlled trial. Euro Surg Res. 2020;61(6):201–8.CrossRef
7.
go back to reference De Schepper H, Coremans G, Denis MA, Dewint P, Duinslaeger M, Gijsen I, Haers P, Komen N, Remue C, Roelandt P, Somers M, Van de Surmont M, Van Kemseke C, De Looze D. Belgian consensus guideline on the management of hemorrhoidal disease. ACTA GASTRO-ENT BELG. 2021;84(1):101–20. De Schepper H, Coremans G, Denis MA, Dewint P, Duinslaeger M, Gijsen I, Haers P, Komen N, Remue C, Roelandt P, Somers M, Van de Surmont M, Van Kemseke C, De Looze D. Belgian consensus guideline on the management of hemorrhoidal disease. ACTA GASTRO-ENT BELG. 2021;84(1):101–20.
8.
9.
go back to reference 9 Shanmugam V, Thaha MA, Rabindranath KS, Campbell KL, Steele RJ, Loudon MA. Systematic review of randomized trials comparing rubber band ligation with excisional haemorrhoidectomy. Brit J Surg. 2005;92(12):1481–7.CrossRefPubMed 9 Shanmugam V, Thaha MA, Rabindranath KS, Campbell KL, Steele RJ, Loudon MA. Systematic review of randomized trials comparing rubber band ligation with excisional haemorrhoidectomy. Brit J Surg. 2005;92(12):1481–7.CrossRefPubMed
10.
go back to reference Kazachenko E, Garmanova T, Derinov A, Markaryan D, Lee H, Magbulova S, Tsarkov P. Preemptive analgesia for hemorrhoidectomy: study protocol for a prospective, randomized, double-blind trial. Trials. 2022;23(1):536.CrossRefPubMedPubMedCentral Kazachenko E, Garmanova T, Derinov A, Markaryan D, Lee H, Magbulova S, Tsarkov P. Preemptive analgesia for hemorrhoidectomy: study protocol for a prospective, randomized, double-blind trial. Trials. 2022;23(1):536.CrossRefPubMedPubMedCentral
11.
go back to reference 11 Bhatti MI, Sajid MS, Baig MK. Milligan-Morgan (Open) versus ferguson haemorrhoidectomy (closed): a systematic review and Meta- analysis of published randomized, controlled trials. World J Surg. 2016;40(6):1509–19.CrossRefPubMed 11 Bhatti MI, Sajid MS, Baig MK. Milligan-Morgan (Open) versus ferguson haemorrhoidectomy (closed): a systematic review and Meta- analysis of published randomized, controlled trials. World J Surg. 2016;40(6):1509–19.CrossRefPubMed
12.
go back to reference Ho YH, Buettner PG. Open compared with closed hemorrhoidectomy: meta-analysis of randomized controlled trials. Tech Coloproctol. 2007;11(2):135–43.CrossRefPubMed Ho YH, Buettner PG. Open compared with closed hemorrhoidectomy: meta-analysis of randomized controlled trials. Tech Coloproctol. 2007;11(2):135–43.CrossRefPubMed
13.
go back to reference Milligan ETC, Morgan CN, Jones LE, Officer R. Surgical anatomy of the anal canal and the operative treatment of hemorrhoids. Lancet. 1937;230:1119–24.CrossRef Milligan ETC, Morgan CN, Jones LE, Officer R. Surgical anatomy of the anal canal and the operative treatment of hemorrhoids. Lancet. 1937;230:1119–24.CrossRef
14.
go back to reference van Tol RR, Kleijnen J, Watson AJM, Jongen J, Altomare DF, Qvist N, Higuero T, Muris JWM, Breukink SO. European Society of Coloproctology: guideline for haemorrhoidal disease. Colorectal Dis. 2020;22(6):650–62.CrossRefPubMed van Tol RR, Kleijnen J, Watson AJM, Jongen J, Altomare DF, Qvist N, Higuero T, Muris JWM, Breukink SO. European Society of Coloproctology: guideline for haemorrhoidal disease. Colorectal Dis. 2020;22(6):650–62.CrossRefPubMed
15.
go back to reference Davis BR, Lee-Kong SA, MigalyJ, Feingold DL, Steele SR. The american society of Colon and rectal Surgeons Clinical Practice Guidelines for the management of hemorrhoids. Dis Colon Rectum. 2018;61(3):284–92.CrossRefPubMed Davis BR, Lee-Kong SA, MigalyJ, Feingold DL, Steele SR. The american society of Colon and rectal Surgeons Clinical Practice Guidelines for the management of hemorrhoids. Dis Colon Rectum. 2018;61(3):284–92.CrossRefPubMed
16.
go back to reference Gallo G, Martellucci J, Sturiale A, Clerico G, Milito G, Marino F, Cocorullo G, Giordano P, Mistrangelo M, Trompetto M. Consensus statement of the italian society of colorectal surgery (SICCR): management and treatment of hemorrhoidal disease. Tech Coloproctol. 2020;24(2):145–64.CrossRefPubMedPubMedCentral Gallo G, Martellucci J, Sturiale A, Clerico G, Milito G, Marino F, Cocorullo G, Giordano P, Mistrangelo M, Trompetto M. Consensus statement of the italian society of colorectal surgery (SICCR): management and treatment of hemorrhoidal disease. Tech Coloproctol. 2020;24(2):145–64.CrossRefPubMedPubMedCentral
17.
go back to reference Lu M, Shi GY, Wang, Wu Y, Liu Y, Wen H. Milligan-Morgan hemorrhoidectomy with anal cushion suspension and partial internal sphincter resection for circumferential mixed hemorrhoids. World J Gastroenterol. 2013;19(30):5011–5.CrossRefPubMedPubMedCentral Lu M, Shi GY, Wang, Wu Y, Liu Y, Wen H. Milligan-Morgan hemorrhoidectomy with anal cushion suspension and partial internal sphincter resection for circumferential mixed hemorrhoids. World J Gastroenterol. 2013;19(30):5011–5.CrossRefPubMedPubMedCentral
18.
go back to reference Abbas ST, Raza A, Muhammad Ch I, Hameed T, Hasham N, Arshad N. Comparison of mean pain score using topical and oral metronidazole in post milligan morgan hemorrhoidectomy patient; a randomized controlled trial. Pak J Med Sci. 2020;36(5):867–71.CrossRefPubMedPubMedCentral Abbas ST, Raza A, Muhammad Ch I, Hameed T, Hasham N, Arshad N. Comparison of mean pain score using topical and oral metronidazole in post milligan morgan hemorrhoidectomy patient; a randomized controlled trial. Pak J Med Sci. 2020;36(5):867–71.CrossRefPubMedPubMedCentral
19.
go back to reference Medina-Gallardo NA, De Castro X, De Caralt-Mestres E, Curbelo-Peña Y, Dardano-Berriel A, Serrat Puyol J, Roura-Poch P, Vallverdu-Cartie H. Infiltration of Bupivacaine and Triamcinolone in Surgical Wounds of Milligan-Morgan Hemorrhoidectomy for Postoperative Pain Control: a double-blind randomized controlled trial. Dis Colon Rectum. 2022;65(8):1034–41.CrossRefPubMed Medina-Gallardo NA, De Castro X, De Caralt-Mestres E, Curbelo-Peña Y, Dardano-Berriel A, Serrat Puyol J, Roura-Poch P, Vallverdu-Cartie H. Infiltration of Bupivacaine and Triamcinolone in Surgical Wounds of Milligan-Morgan Hemorrhoidectomy for Postoperative Pain Control: a double-blind randomized controlled trial. Dis Colon Rectum. 2022;65(8):1034–41.CrossRefPubMed
20.
go back to reference Haksal MC, Çiftci A, Tiryaki Ç, Yazıcıoğlu MB, Özyıldız M, Yıldız SY. Comparison of the reliability and efficacy of LigaSure hemorrhoidectomy and a conventional Milligan-Morgan hemorrhoidectomy in the surgical treatment of grade 3 and 4 hemorrhoids. Turkish J Surg. 2017;33(4):233–6.CrossRef Haksal MC, Çiftci A, Tiryaki Ç, Yazıcıoğlu MB, Özyıldız M, Yıldız SY. Comparison of the reliability and efficacy of LigaSure hemorrhoidectomy and a conventional Milligan-Morgan hemorrhoidectomy in the surgical treatment of grade 3 and 4 hemorrhoids. Turkish J Surg. 2017;33(4):233–6.CrossRef
21.
go back to reference Gerbershagen HJ, Aduckathil S, van Wijck AJ, Peelen LM, Kalkman CJ, Meissner W. Pain intensity on the first day after surgery: a prospective cohort study comparing 179 surgical procedures. Anesthesiology. 2013;118(4):934–44.CrossRefPubMed Gerbershagen HJ, Aduckathil S, van Wijck AJ, Peelen LM, Kalkman CJ, Meissner W. Pain intensity on the first day after surgery: a prospective cohort study comparing 179 surgical procedures. Anesthesiology. 2013;118(4):934–44.CrossRefPubMed
22.
go back to reference Medina-Gallardo A, Curbelo-Peña Y, De Castro X, Roura-Poch P, Roca-Closa J, De Caralt-Mestres E. Is the severe pain after Milligan-Morgan hemorrhoidectomy still currently remaining a major postoperative problem despite being one of the oldest surgical techniques described? A case series of 117 consecutive patients. Int J Surg Case Rep. 2017;30:73–5.CrossRefPubMed Medina-Gallardo A, Curbelo-Peña Y, De Castro X, Roura-Poch P, Roca-Closa J, De Caralt-Mestres E. Is the severe pain after Milligan-Morgan hemorrhoidectomy still currently remaining a major postoperative problem despite being one of the oldest surgical techniques described? A case series of 117 consecutive patients. Int J Surg Case Rep. 2017;30:73–5.CrossRefPubMed
23.
go back to reference De Nardi P, Capretti G, Corsaro A, Staudacher C. A prospective, randomized trial comparing the short- and long-term results of doppler-guided transanal hemorrhoid dearterialization with mucopexy versus excision hemorrhoidectomy for grade III hemorrhoids. Dis Colon Rectum. 2014;57(3):348–53.CrossRefPubMed De Nardi P, Capretti G, Corsaro A, Staudacher C. A prospective, randomized trial comparing the short- and long-term results of doppler-guided transanal hemorrhoid dearterialization with mucopexy versus excision hemorrhoidectomy for grade III hemorrhoids. Dis Colon Rectum. 2014;57(3):348–53.CrossRefPubMed
24.
go back to reference Ferrandis C, De Faucal D, Fabreguette JM, Borie F. Efficacy of Doppler-guided hemorrhoidal artery ligation with mucopexy, in the short and long terms for patients with hemorrhoidal disease. Tech Coloproctol. 2020;24(2):165–71.CrossRefPubMed Ferrandis C, De Faucal D, Fabreguette JM, Borie F. Efficacy of Doppler-guided hemorrhoidal artery ligation with mucopexy, in the short and long terms for patients with hemorrhoidal disease. Tech Coloproctol. 2020;24(2):165–71.CrossRefPubMed
25.
go back to reference Schuurman JP, Borel Rinkes IH, Go PM. Hemorrhoidal artery ligation procedure with or without Doppler transducer in grade II and III hemorrhoidal disease: a blinded randomized clinical trial. Ann Surg. 2012;255(5):840–5.CrossRefPubMed Schuurman JP, Borel Rinkes IH, Go PM. Hemorrhoidal artery ligation procedure with or without Doppler transducer in grade II and III hemorrhoidal disease: a blinded randomized clinical trial. Ann Surg. 2012;255(5):840–5.CrossRefPubMed
26.
go back to reference Qamar Naqvi SR, Qamar Naqvi SS, Rashid MM, Sheikh IA, Ali M, Nafees AUA. Haemorrhoidal artery ligation operation without Doppler Guidance. J Ayub Med Coll Abbottabad. 2018;30(Suppl 1):664–S667. Qamar Naqvi SR, Qamar Naqvi SS, Rashid MM, Sheikh IA, Ali M, Nafees AUA. Haemorrhoidal artery ligation operation without Doppler Guidance. J Ayub Med Coll Abbottabad. 2018;30(Suppl 1):664–S667.
27.
go back to reference Li B, Li X, Zhang Q, Zhao WB. Milligan-Morgan procedure combined with hemorrhoidal artery ligation in the treatment of III-IV degree mixed hemorrhoids. China Med Pharm. 2022;12(8):133–6. Li B, Li X, Zhang Q, Zhao WB. Milligan-Morgan procedure combined with hemorrhoidal artery ligation in the treatment of III-IV degree mixed hemorrhoids. China Med Pharm. 2022;12(8):133–6.
28.
go back to reference Symeonidis D, Spyridakis M, Zacharoulis D, Tzovaras G, Samara AA, Valaroutsos A, Diamantis A, Tepetes K. Milligan-Morgan hemorrhoidectomy vs. hemorrhoid artery ligation and recto-anal repair: a comparative study. BMC Surg. 2022;22(1):416.CrossRefPubMedPubMedCentral Symeonidis D, Spyridakis M, Zacharoulis D, Tzovaras G, Samara AA, Valaroutsos A, Diamantis A, Tepetes K. Milligan-Morgan hemorrhoidectomy vs. hemorrhoid artery ligation and recto-anal repair: a comparative study. BMC Surg. 2022;22(1):416.CrossRefPubMedPubMedCentral
29.
go back to reference Ratto C, Campennì P, Papeo F, Donisi L, Litta F, Parello A. Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: a single-center study on 1000 consecutive cases and a review of the literature. Tech Coloproctol. 2017;21(12):953–62.CrossRefPubMedPubMedCentral Ratto C, Campennì P, Papeo F, Donisi L, Litta F, Parello A. Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: a single-center study on 1000 consecutive cases and a review of the literature. Tech Coloproctol. 2017;21(12):953–62.CrossRefPubMedPubMedCentral
30.
go back to reference Karkalemis K, Chalkias PL, Kasouli A, Chatzaki E, Papanikolaou S, Dedemadi G. Safety and effectiveness of hemorrhoidal artery ligation using the HAL-RAR technique for hemorrhoidal disease.LANGENBECK. ARCH SURG. 2021;406(7):2489–95.CrossRef Karkalemis K, Chalkias PL, Kasouli A, Chatzaki E, Papanikolaou S, Dedemadi G. Safety and effectiveness of hemorrhoidal artery ligation using the HAL-RAR technique for hemorrhoidal disease.LANGENBECK. ARCH SURG. 2021;406(7):2489–95.CrossRef
Metadata
Title
Milligan-Morgan hemorrhoidectomy combined with non-doppler hemorrhoidal artery ligation for the treatment of grade III/IV hemorrhoids: a single centre retrospective study
Authors
Qing Long
Yong Wen
Jun Li
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2023
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-023-02933-x

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