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Published in: BMC Geriatrics 1/2023

Open Access 01-12-2023 | Mild Neurocognitive Disorder | Study Protocol

Study protocol for “In-vehicle sensors to detect changes in cognition of older drivers”

Authors: Ruth Tappen, David Newman, Monica Rosselli, Jinwoo Jang, Borko Furht, KwangSoo Yang, Seyedeh Gol Ara Ghoreishi, Jiannan Zhai, Joshua Conniff, Muhammad Tanveer Jan, Sonia Moshfeghi, Somi Panday, Kelley Jackson, Marie Adonis-Rizzo

Published in: BMC Geriatrics | Issue 1/2023

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Abstract

Background

Driving is a complex behavior that may be affected by early changes in the cognition of older individuals. Early changes in driving behavior may include driving more slowly, making fewer and shorter trips, and errors related to inadequate anticipation of situations. Sensor systems installed in older drivers’ vehicles may detect these changes and may generate early warnings of possible changes in cognition.

Method

A naturalistic longitudinal design is employed to obtain continuous information on driving behavior that will be compared with the results of extensive cognitive testing conducted every 3 months for 3 years. A driver facing camera, forward facing camera, and telematics unit are installed in the vehicle and data downloaded every 3 months when the cognitive tests are administered.

Results

Data processing and analysis will proceed through a series of steps including data normalization, adding information on external factors (weather, traffic conditions), and identifying critical features (variables). Traditional prediction modeling results will be compared with Recurring Neural Network (RNN) approach to produce Driver Behavior Indices (DBIs), and algorithms to classify drivers within age, gender, ethnic group membership, and other potential group characteristics.

Conclusion

It is well established that individuals with progressive dementias are eventually unable to drive safely, yet many remain unaware of their cognitive decrements. Current screening and evaluation services can test only a small number of individuals with cognitive concerns, missing many who need to know if they require treatment. Given the increasing number of sensors being installed in passenger vehicles and pick-up trucks and their increasing acceptability, reconfigured in-vehicle sensing systems could provide widespread, low-cost early warnings of cognitive decline to the large number of older drivers on the road in the U.S. The proposed testing and evaluation of a readily and rapidly available, unobtrusive in-vehicle sensing system could provide the first step toward future widespread, low-cost early warnings of cognitive change for this large number of older drivers in the U.S. and elsewhere.
Literature
1.
go back to reference Rajan KB, Weuve J, Barnes LL, McAninch EA, Wilson RS, Evans DA. Population estimate of people with clinical Alzheimer’s disease and mild cognitive impairment in the United States (2020–2060). U.S. National Library of Medicine. Available from: https://pubmed.ncbi.nlm.nih.gov/34043283/. Cited 2023 Sept 6. Rajan KB, Weuve J, Barnes LL, McAninch EA, Wilson RS, Evans DA. Population estimate of people with clinical Alzheimer’s disease and mild cognitive impairment in the United States (2020–2060). U.S. National Library of Medicine. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​34043283/​. Cited 2023 Sept 6.
5.
go back to reference Chee JN, Rapoport MJ, Molnar F, Herrmann N, O’Neill D, Marottoli R, Mitchell S, Tant M, Dow J, Ayotte D, Lanctôt KL, McFadden R, Taylor JP, Donaghy PC, Olsen K, Classen S, Elzohairy Y, Carr DB. Update on the risk of motor vehicle collision or driving impairment with dementia: a collaborative international systematic review and meta-analysis. U.S. National Library of Medicine; 2017. Available from: https://pubmed.ncbi.nlm.nih.gov/28917504/. Cited 2023 Sept 6. Chee JN, Rapoport MJ, Molnar F, Herrmann N, O’Neill D, Marottoli R, Mitchell S, Tant M, Dow J, Ayotte D, Lanctôt KL, McFadden R, Taylor JP, Donaghy PC, Olsen K, Classen S, Elzohairy Y, Carr DB. Update on the risk of motor vehicle collision or driving impairment with dementia: a collaborative international systematic review and meta-analysis. U.S. National Library of Medicine; 2017. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​28917504/​. Cited 2023 Sept 6.
10.
go back to reference Seelye A, Mattek N, Sharma N, Witter P, Brenner A, Wild K, Dodge H, Kaye J. Passive assessment of routine driving with unobtrusive sensors: a new approach for identifying and monitoring functional level in normal aging and mild cognitive impairment. U.S. National Library of Medicine; 2017. Available from: https://pubmed.ncbi.nlm.nih.gov/28731434/. Cited 2023 Sept 6. Seelye A, Mattek N, Sharma N, Witter P, Brenner A, Wild K, Dodge H, Kaye J. Passive assessment of routine driving with unobtrusive sensors: a new approach for identifying and monitoring functional level in normal aging and mild cognitive impairment. U.S. National Library of Medicine; 2017. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​28731434/​. Cited 2023 Sept 6.
11.
go back to reference Di X, Shi R, DiGuiseppi C, Eby DW, Hill LL, Mielenz TJ, Molnar LJ, Strogatz D, Andrews HF, Goldberg TE, Lang BH, Kim M, Li G. Using naturalistic driving data to predict mild cognitive impairment and dementia: preliminary findings from the longitudinal research on Aging Drivers (LongROAD) study. U.S. National Library of Medicine; 2021. Available from: https://pubmed.ncbi.nlm.nih.gov/33922735/. Cited 2023 Sept 6. Di X, Shi R, DiGuiseppi C, Eby DW, Hill LL, Mielenz TJ, Molnar LJ, Strogatz D, Andrews HF, Goldberg TE, Lang BH, Kim M, Li G. Using naturalistic driving data to predict mild cognitive impairment and dementia: preliminary findings from the longitudinal research on Aging Drivers (LongROAD) study. U.S. National Library of Medicine; 2021. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​33922735/​. Cited 2023 Sept 6.
13.
go back to reference Davis JD, Babulal GM, Papandonatos GD, Burke EM, Rosnick CB, Ott BR, Roe CM. Evaluation of naturalistic driving behavior using in-vehicle monitoring technology in preclinical and early Alzheimer’s disease. U.S. National Library of Medicine; 2020. Available from: https://pubmed.ncbi.nlm.nih.gov/33192943/. Cited 2023 Sept 6. Davis JD, Babulal GM, Papandonatos GD, Burke EM, Rosnick CB, Ott BR, Roe CM. Evaluation of naturalistic driving behavior using in-vehicle monitoring technology in preclinical and early Alzheimer’s disease. U.S. National Library of Medicine; 2020. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​33192943/​. Cited 2023 Sept 6.
14.
go back to reference Huisingh C, Owsley C, Wadley VG, Levitan EB, Irvin MR, MacLennan P, McGwin G. General cognitive impairment as a risk factor for motor vehicle collision involvement: a prospective population-based study. U.S. National Library of Medicine; 2018. Available from: https://pubmed.ncbi.nlm.nih.gov/29600251/. Cited 2023 Sept 6. Huisingh C, Owsley C, Wadley VG, Levitan EB, Irvin MR, MacLennan P, McGwin G. General cognitive impairment as a risk factor for motor vehicle collision involvement: a prospective population-based study. U.S. National Library of Medicine; 2018. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​29600251/​. Cited 2023 Sept 6.
17.
go back to reference Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, Cummings JL, Chertkow H. The Montreal Cognitive Assessment, MOCA: a brief screening tool for mild cognitive impairment. U.S. National Library of Medicine; 2005. Available from: https://pubmed.ncbi.nlm.nih.gov/15817019/. Cited 2023 Sept 6. Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, Cummings JL, Chertkow H. The Montreal Cognitive Assessment, MOCA: a brief screening tool for mild cognitive impairment. U.S. National Library of Medicine; 2005. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​15817019/​. Cited 2023 Sept 6.
24.
go back to reference Loewenstein DA, Curiel RE, Greig MT, Bauer RM, Rosado M, Bowers D, Wicklund M, Crocco E, Pontecorvo M, Joshi AD, Rodriguez R, Barker WW, Hidalgo J, Duara R. A novel cognitive stress test for the detection of preclinical Alzheimer disease: discriminative properties and relation to amyloid load. U.S. National Library of Medicine; 2016. Available from: https://pubmed.ncbi.nlm.nih.gov/27160985/. Cited 2023 Sept 7. Loewenstein DA, Curiel RE, Greig MT, Bauer RM, Rosado M, Bowers D, Wicklund M, Crocco E, Pontecorvo M, Joshi AD, Rodriguez R, Barker WW, Hidalgo J, Duara R. A novel cognitive stress test for the detection of preclinical Alzheimer disease: discriminative properties and relation to amyloid load. U.S. National Library of Medicine; 2016. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​27160985/​. Cited 2023 Sept 7.
27.
go back to reference Possin KL, Laluz VR, Alcantar OZ, Miller BL, Kramer JH. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer’s disease and behavioral variant frontotemporal dementia. U.S. National Library of Medicine; 2011. Available from: https://pubmed.ncbi.nlm.nih.gov/21029744/. Cited 2023 Sept 7. Possin KL, Laluz VR, Alcantar OZ, Miller BL, Kramer JH. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer’s disease and behavioral variant frontotemporal dementia. U.S. National Library of Medicine; 2011. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​21029744/​. Cited 2023 Sept 7.
28.
go back to reference Gollan TH, Weissberger GH, Runnqvist E, Montoya RI, Cera CM. Self-ratings of spoken language dominance: a multi-lingual naming test (MINT) and preliminary norms for young and aging Spanish-English bilinguals. U.S. National Library of Medicine; 2012. Available from: https://pubmed.ncbi.nlm.nih.gov/25364296/. Cited 2023 Sept 7. Gollan TH, Weissberger GH, Runnqvist E, Montoya RI, Cera CM. Self-ratings of spoken language dominance: a multi-lingual naming test (MINT) and preliminary norms for young and aging Spanish-English bilinguals. U.S. National Library of Medicine; 2012. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​25364296/​. Cited 2023 Sept 7.
31.
go back to reference Benton AL, Hamsher DS, Sivan AB. Contributions to Neuropsychological Assessment. A Clinical Manual (2nd ed.). New York: Oxford University Press; 1994. Benton AL, Hamsher DS, Sivan AB. Contributions to Neuropsychological Assessment. A Clinical Manual (2nd ed.). New York: Oxford University Press; 1994.
36.
go back to reference van Harten AC, Mielke MM, Swenson-Dravis DM, Hagen CE, Edwards KK, Roberts RO, Geda YE, Knopman DS, Petersen RC. Subjective cognitive decline and risk of MCI: the Mayo Clinic Study of Aging. U.S. National Library of Medicine; 2018. Available from: https://pubmed.ncbi.nlm.nih.gov/29959257/. Cited 2023 Sept 7. van Harten AC, Mielke MM, Swenson-Dravis DM, Hagen CE, Edwards KK, Roberts RO, Geda YE, Knopman DS, Petersen RC. Subjective cognitive decline and risk of MCI: the Mayo Clinic Study of Aging. U.S. National Library of Medicine; 2018. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​29959257/​. Cited 2023 Sept 7.
37.
40.
go back to reference CogState Company Ltd. CogState TM. Melbourne: CogState Limited; 2009. CogState Company Ltd. CogState TM. Melbourne: CogState Limited; 2009.
43.
44.
go back to reference Duara R, Loewenstein DA, Greig M, Acevedo A, Potter E, Appel J, Raj A, Schinka J, Schofield E, Barker W, Wu Y, Potter H. Reliability and validity of an algorithm for the diagnosis of normal cognition, mild cognitive impairment, and dementia: implications for multicenter research studies. U.S. National Library of Medicine; 2010. Available from: https://pubmed.ncbi.nlm.nih.gov/20306566/. Cited 2023 Sept 7. Duara R, Loewenstein DA, Greig M, Acevedo A, Potter E, Appel J, Raj A, Schinka J, Schofield E, Barker W, Wu Y, Potter H. Reliability and validity of an algorithm for the diagnosis of normal cognition, mild cognitive impairment, and dementia: implications for multicenter research studies. U.S. National Library of Medicine; 2010. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​20306566/​. Cited 2023 Sept 7.
45.
go back to reference Plate JDJ, van de Leur RR, Leenen LPH, Hietbrink F, Peelen LM, Eijkemans MJC. Incorporating repeated measurements into prediction models in the Critical Care Setting: a Framework, systematic review and meta-analysis. U.S. National Library of Medicine; 2019. Available from: https://pubmed.ncbi.nlm.nih.gov/31655567/. Cited 2023 Sept 7. Plate JDJ, van de Leur RR, Leenen LPH, Hietbrink F, Peelen LM, Eijkemans MJC. Incorporating repeated measurements into prediction models in the Critical Care Setting: a Framework, systematic review and meta-analysis. U.S. National Library of Medicine; 2019. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​31655567/​. Cited 2023 Sept 7.
46.
go back to reference Newman D, Newman I, Hitchcock JH. Cognitive analytics: concepts, methodologies, tools, and applications. 2020. Newman D, Newman I, Hitchcock JH. Cognitive analytics: concepts, methodologies, tools, and applications. 2020.
48.
go back to reference Goodfellow I, Bengio Y, Courville A. Deep learning. 2016. Goodfellow I, Bengio Y, Courville A. Deep learning. 2016.
50.
go back to reference Hsieh HF, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277–88.CrossRefPubMed Hsieh HF, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277–88.CrossRefPubMed
Metadata
Title
Study protocol for “In-vehicle sensors to detect changes in cognition of older drivers”
Authors
Ruth Tappen
David Newman
Monica Rosselli
Jinwoo Jang
Borko Furht
KwangSoo Yang
Seyedeh Gol Ara Ghoreishi
Jiannan Zhai
Joshua Conniff
Muhammad Tanveer Jan
Sonia Moshfeghi
Somi Panday
Kelley Jackson
Marie Adonis-Rizzo
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2023
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-023-04550-5

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