Published in:
01-11-2014 | Letter to the Editor
Midodrine Efficacy in Orthostatic Hypotension
Authors:
W. Singer, MD, M. J. Joyner, MD, P. Sandroni, MD, PhD, E. E. Benarroch, MD, R. D. Fealey, MD, J. Mandrekar, PhD, P. A. Low, MD
Published in:
Journal of General Internal Medicine
|
Issue 11/2014
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Excerpt
To the Editors—We recently came across the review article by Parsaik et al. “Midodrine for Orthostatic Hypotension: A Systematic Review and Meta-Analysis of Clinical Trials” (J Gen Intern Med 28(11): 1496–503), and feel obligated to comment on several deficiencies of this work. Unfortunately, the article was published under the Mayo Clinic name by former trainees without expert supervision, since none of the autonomic experts at Mayo who author this letter were in any way involved in conducting the study or guiding its interpretation. The deficiencies are major and reflect poorly on Mayo Clinic investigators. Furthermore, this article needs rectification—both of content and interpretation—to avoid potential damage to the future of the first US Food and Drug Administration (FDA)-approved and arguably single most efficient pharmacologic intervention for orthostatic hypotension (OH) to date. …